Question 1

How many shares of ARWR does D. E. Shaw & Co., Inc. own?

Accepted Answer

As of 2026-Q2, D. E. Shaw & Co., Inc. holds 431,560 shares of ARWR (ARROWHEAD PHARMACEUTICALS IN).

Question 2

What is D. E. Shaw & Co., Inc.'s ARWR position worth?

Accepted Answer

As of 2026-Q2, D. E. Shaw & Co., Inc.'s ARWR position is worth $35.2M.

Question 3

Is D. E. Shaw & Co., Inc. buying or selling ARWR?

Accepted Answer

In 2026-Q2, D. E. Shaw & Co., Inc. decreased their ARWR position (-63.5% change in shares).

Question 4

When did D. E. Shaw & Co., Inc. first buy ARWR?

Accepted Answer

Based on available 13F filings, D. E. Shaw & Co., Inc. first reported a position in ARWR in 2025-Q3. They have held the position across 25 quarters.

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2026-Q2 Latest	Decreased	431,560	-63.5%	$35.2M	0.0%	$81.51	0
2026-Q1	Increased	1.2M	+710.5%	$74.2M	0.0%	$64.10	48
2025-Q4	Increased	146,064	+619.5%	$9.7M	0.0%	$67.25	45
2025-Q3	New	20,301	—	$700,181	0.0%	$33.78	34