Question 1

Does D. E. Shaw own ARWR stock?

Accepted Answer

Yes. As of its Q2 2026 13F, D. E. Shaw holds 431,560 shares of ARWR (Arrowhead Pharmaceuticals in), worth $35.2M.

Question 2

How many shares of ARWR does D. E. Shaw own?

Accepted Answer

As of its Q2 2026 13F, D. E. Shaw holds 431,560 shares of ARWR (Arrowhead Pharmaceuticals in).

Question 3

What is D. E. Shaw's ARWR position worth?

Accepted Answer

As of its Q2 2026 13F, D. E. Shaw's ARWR position is worth $35.2M.

Question 4

Is D. E. Shaw buying or selling ARWR?

Accepted Answer

In Q2 2026, D. E. Shaw reduced its ARWR position by 752,278 shares (-63.6%).

Question 5

When did D. E. Shaw first buy ARWR?

Accepted Answer

D. E. Shaw already held ARWR in its Q4 2018 13F, the earliest on record, and has listed it in 21 quarterly 13F filings.

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2026-Q2 Latest	Decreased	431,560	-63.5%	$35.2M	0.0%	$81.51	0
2026-Q1	Increased	1.2M	+710.5%	$74.2M	0.0%	$62.70	48
2025-Q4	Increased	146,064	+619.5%	$9.7M	0.0%	$66.39	45
2025-Q3	New	20,301	—	$700,181	0.0%	$34.49	34