ADAGE CAPITAL PARTNERS GP, L.L.C.

View all activity View 13F on SEC

Data as of Q4 2025

Institutional investor tracked via SEC 13F filings. Portfolio snapshot as of 2025-12-31.SEC EDGAR Source

Assets Under Management

$66.1B

Total Positions

904

New This Quarter

182

Filing Period

2025-12-31

Portfolio Allocation

Top holdings by portfolio weight

NVDA6.28%

AAPL5.44%

MSFT4.85%

AMZN3.17%

GOOGL2.49%

AVGO2.21%

META2.01%

GOOG1.98%

TSLA1.68%

LLY1.35%

Other10.80%

Position Outcomes

Best and worst performing positions by estimated return

Top Winners

CDTX6Q held

CIDARA THERAPEUTICS INC

Avg $25.49 · $51.4M est. P&L

Est. P&L

+766.09%

PRAX9Q held

PRAXIS PRECISION MEDICINES I

Avg $41.86 · $246.3M est. P&L

Est. P&L

+609.63%

MU29Q held

Micron Technology Inc

Avg $45.56 · $274.5M est. P&L

Est. P&L

+542.35%

Top Losers

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View plans

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Top Holdings(Showing 25 of 902 — sorted by value)

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Activity:

Stock	Shares	Value	Weight	Price Trend	Avg Buy	Est. P&L	Held	Conviction
NVDA NVIDIA Corp	22.3M	$4.2B	6.3%	—	$112.51	+66.68%	29 qtrs	Decreased 0
AAPL Apple Inc	13.2M	$3.6B	5.4%	—	$96.76	+181.95%	29 qtrs	Decreased 0
MSFT Microsoft Corp	6.6M	$3.2B	4.9%	—	$110.11	+342.74%	29 qtrs	Decreased 0
AMZN Amazon.com Inc	9.1M	$2.1B	3.2%	—	$122.77	+89.40%	29 qtrs	Decreased 0
GOOGL Alphabet Inc	5.3M	$1.6B	2.5%	—	$96.17	+226.33%	29 qtrs	Decreased 0
AVGO Broadcom Inc	4.2M	$1.5B	2.2%	—	$165.82	+110.99%	29 qtrs	Increased 55
META Meta Platforms Inc	2M	$1.3B	2.0%	—	$185.19	+259.60%	29 qtrs	Increased 55
GOOG Alphabet Inc	4.2M	$1.3B	2.0%	—	$98.06	+220.78%	29 qtrs	Decreased 0
TSLA Tesla Inc	2.5M	$1.1B	1.7%	—	$262.72	+72.97%	21 qtrs	Increased 51
LLY Eli Lilly & Co	832,292	$894.4M	1.4%	—	$330.58	+226.08%	29 qtrs	Increased 52
BRK/B Berkshire Hathaway Inc	1.6M	$826.1M	1.3%	—	—	—	29 qtrs	Decreased 0
JPM JPMORGAN CHASE & CO.	2.4M	$782.5M	1.2%	—	$97.85	+229.04%	29 qtrs	Decreased 0
COP ConocoPhillips	7M	$658.8M	1.0%	—	$86.52	+8.76%	20 qtrs	Increased 52
V Visa Inc	1.5M	$528.6M	0.8%	—	$190.54	+85.21%	29 qtrs	Decreased 0
JNJ Johnson & Johnson	2.2M	$457.5M	0.7%	—	$162.64	+27.22%	29 qtrs	Decreased 0
RPRX Royalty Pharma PLC	11.7M	$453.7M	0.7%	—	$33.85	+15.18%	23 qtrs	Decreased 0
WMT Walmart Inc	3.9M	$431.5M	0.7%	—	$60.09	+86.25%	29 qtrs	Decreased 0
MA Mastercard Inc	730,560	$417.1M	0.6%	—	$245.61	+134.74%	29 qtrs	Decreased 0
PG Procter & Gamble Co/The	2.8M	$404.5M	0.6%	—	$127.01	+12.61%	29 qtrs	Decreased 0
NFLX Netflix Inc	4M	$378.4M	0.6%	—	$88.36	+6.14%	29 qtrs	Increased 71
PLTR Palantir Technologies Inc	2.1M	$367M	0.6%	—	$49.77	+263.39%	6 qtrs	Decreased 0
HD Home Depot Inc/The	1.1M	$365.3M	0.6%	—	$287.97	+20.27%	29 qtrs	Decreased 0
ORCL Oracle Corp	1.9M	$364.5M	0.6%	—	$97.69	+101.34%	29 qtrs	Increased 52
BAC Bank of America Corp	6.5M	$357.8M	0.5%	—	$29.21	+89.24%	29 qtrs	Decreased 0
ABBV AbbVie Inc	1.5M	$344.7M	0.5%	—	$141.80	+60.72%	23 qtrs	Decreased 0
Showing 25 of 902 results.PROUpgrade to see all →

Accumulation Streaks

Positions with 2+ consecutive quarters of increases — persistent directional conviction.

Security

CNTACENTESSA PHARMACEUTICALS PLC

Q2 2024 → Q4 2025+9M shares+$256.7M

CVECENOVUS ENERGY INC

Q3 2024 → Q4 2025+2.5M shares+$33.8M

JBTMJBT MAREL CORPORATION

Q3 2024 → Q4 2025+333,318 shares+$68.4M

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer