Does Janus Henderson own VRTX stock?

Yes. As of its Q1 2026 13F, Janus Henderson holds 2,131,527 shares of VRTX (Vertex Pharmaceuticals), worth $951.8M.

How many shares of VRTX does Janus Henderson own?

As of its Q1 2026 13F, Janus Henderson holds 2,131,527 shares of VRTX (Vertex Pharmaceuticals).

As of its Q1 2026 13F, Janus Henderson's VRTX position is worth $951.8M.

In Q1 2026, Janus Henderson reduced its VRTX position by 90,426 shares (-4.1%).

Janus Henderson already held VRTX in its Q2 2019 13F, the earliest on record, and has listed it in 28 quarterly 13F filings.

Position history for Janus Henderson Group Ltd.'s holdings in VERTEX PHARMACEUTICALS INC

Current Value

$951.8M

Current Shares

2.1M

Total Value Change

+$759.3M

Total Shares Change

+1.1M

Quarter-by-Quarter History

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2026-Q1 Latest	Decreased	2.1M	-4.1%	$951.8M	0.5%	$446.54	0
2025-Q4	Increased	2.2M	+4.8%	$1B	0.5%	$453.36	40
2025-Q3	Decreased	2.1M	-19.1%	$829.9M	0.4%	$391.64	0
2025-Q2	Decreased	2.6M	-4.7%	$1.2B	0.6%	$445.20	0
2025-Q1	Decreased	2.7M	-3.0%	$1.4B	0.7%	$484.82	0
2024-Q4	Increased	2.8M	+12.6%	$1.1B	0.6%	$402.70	51
2024-Q3	Increased	2.5M	+4.1%	$1.2B	0.6%	$465.08	47
2024-Q2	Decreased	2.4M	-6.5%	$1.1B	0.6%	$468.72	0
2024-Q1	Increased	2.6M	+10.4%	$1.1B	0.6%	$418.01	50
2023-Q4	Increased	2.3M	+41.1%	$952.1M	0.6%	$406.89	60
2023-Q3	Increased	1.7M	+15.6%	$576.8M	0.4%	$347.74	43
2023-Q2	Increased	1.4M	+5.0%	$505M	0.3%	$351.91	39
2023-Q1	Decreased	1.4M	-1.4%	$430.6M	0.3%	$315.07	0
2022-Q4	Decreased	1.4M	-7.7%	$400.1M	0.3%	$288.78	0
2022-Q3	Decreased	1.5M	-8.4%	$434.8M	0.3%	$289.54	0
2022-Q2	Decreased	1.6M	-9.2%	$461.9M	0.3%	$281.79	0
2022-Q1	Decreased	1.8M	-9.3%	$471.2M	0.2%	$260.97	0
2021-Q4	Decreased	2M	-6.8%	$437.2M	0.2%	$219.60	0
2021-Q3	Decreased	2.1M	-50.2%	$387.2M	0.2%	$181.39	0
2021-Q2	Decreased	4.3M	-4.9%	$864.7M	0.4%	$201.63	0
2021-Q1	Increased	4.5M	+8.2%	$968.9M	0.4%	$214.89	41
2020-Q4	Increased	4.2M	+119.2%	$984.7M	0.5%	$236.34	62
2020-Q3	Decreased	1.9M	-3.2%	$517.3M	0.3%	$272.12	0
2020-Q2	Increased	2M	+4.9%	$570M	0.3%	$290.31	39
2020-Q1	Decreased	1.9M	-12.3%	$445.4M	0.3%	$237.95	0
2019-Q4	Increased	2.1M	+14.0%	$467.4M	0.2%	$218.95	43
2019-Q3	Increased	1.9M	+78.3%	$317.2M	0.2%	$169.42	56
2019-Q2	First report	1M	-	$192.5M	0.1%	$183.38	0

Other major holders of VRTX: Capital World Investors