Question 1

How many shares of QURE does TWO SIGMA ADVISERS, LP own?

Accepted Answer

As of 2025-Q4, TWO SIGMA ADVISERS, LP holds 1.1M shares of QURE (uniQure N.V.).

Question 2

What is TWO SIGMA ADVISERS, LP's QURE position worth?

Accepted Answer

As of 2025-Q4, TWO SIGMA ADVISERS, LP's QURE position is worth $26.6M.

Question 3

Is TWO SIGMA ADVISERS, LP buying or selling QURE?

Accepted Answer

In 2025-Q4, TWO SIGMA ADVISERS, LP increased their QURE position (+171.2% change in shares).

Question 4

When did TWO SIGMA ADVISERS, LP first buy QURE?

Accepted Answer

Based on available 13F filings, TWO SIGMA ADVISERS, LP first reported a position in QURE in 2024-Q3. They have held the position across 20 quarters.

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2025-Q4 Latest	Increased	1.1M	+171.2%	$26.6M	0.1%	$23.78	46
2025-Q3	Decreased	409,500	-37.9%	$23.9M	0.0%	$59.40	0
2025-Q2	Decreased	659,700	-1.3%	$9.2M	0.0%	$13.86	0
2025-Q1	Decreased	668,494	-11.7%	$7.1M	0.0%	$12.47	0
2024-Q4	Increased	756,900	+1.4%	$13.4M	0.0%	$17.22	28
2024-Q3	Increased	746,500	+247.7%	$3.7M	0.0%	$5.08	43