Question 1

Does Two Sigma Advisers own QURE stock?

Accepted Answer

Yes. As of its Q4 2025 13F, Two Sigma Advisers holds 1,110,400 shares of QURE (Uniqure), worth $26.6M.

Question 2

How many shares of QURE does Two Sigma Advisers own?

Accepted Answer

As of its Q4 2025 13F, Two Sigma Advisers holds 1,110,400 shares of QURE (Uniqure).

Question 3

What is Two Sigma Advisers' QURE position worth?

Accepted Answer

As of its Q4 2025 13F, Two Sigma Advisers' QURE position is worth $26.6M.

Question 4

Is Two Sigma Advisers buying or selling QURE?

Accepted Answer

In Q4 2025, Two Sigma Advisers increased its QURE position by 700,900 shares (+171.2%).

Question 5

When did Two Sigma Advisers first buy QURE?

Accepted Answer

Two Sigma Advisers already held QURE in its Q4 2018 13F, the earliest on record, and has listed it in 19 quarterly 13F filings.

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2025-Q4 Latest	Increased	1.1M	+171.2%	$26.6M	0.1%	$23.93	46
2025-Q3	Decreased	409,500	-37.9%	$23.9M	0.0%	$58.37	0
2025-Q2	Decreased	659,700	-1.3%	$9.2M	0.0%	$13.94	0
2025-Q1	Decreased	668,494	-11.7%	$7.1M	0.0%	$10.60	0
2024-Q4	Increased	756,900	+1.4%	$13.4M	0.0%	$17.66	28
2024-Q3	Increased	746,500	+247.7%	$3.7M	0.0%	$4.93	43