RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q1 2021

Top Holdings111 positions

Checking export access…
Activity:

ROCKET PHARMACEUTICALS INC

15.7M$697.3M10.9%$18.07+145.56%
9 qtrssince 2019-Q1
Decreased
0
SPYSPY
Unit

STATE STR SPDR S&P 500 ETF T

946,255$375M5.9%$368.300.00%
1 qtr
New
96

VERICEL CORP

4.5M$251M3.9%$17.15+223.99%
9 qtrssince 2019-Q1
Unchanged
0

PTC THERAPEUTICS INC

5.3M$250.7M3.9%$41.73+13.48%
9 qtrssince 2019-Q1
Increased
69

ALNYLAM PHARMACEUTICALS INC

1.7M$237.7M3.7%$81.30+73.66%
9 qtrssince 2019-Q1
Increased
56
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

1.3M$228.4M3.6%——
9 qtrssince 2019-Q1
Increased
70
DRNADRNADelisted

DICERNA PHARMACEUTICALS INC

7.5M$190.8M3.0%——
9 qtrssince 2019-Q1
Increased
54

ILLUMINA INC

481,956$185.1M2.9%$341.81+9.30%
3 qtrssince 2020-Q3
Increased
67

NATERA INC

1.7M$173.9M2.7%$38.24+165.54%
7 qtrssince 2019-Q3
Unchanged
0
DMTKQDMTKQDelisted

DERMTECH INC

3.1M$158.4M2.5%——
7 qtrssince 2019-Q3
Increased
56

ESTABLISHMENT LABS HLDGS INC

2.3M$145M2.3%$22.02+183.99%
9 qtrssince 2019-Q1
Unchanged
0

STOKE THERAPEUTICS INC

3.6M$141.5M2.2%$29.39+32.15%
8 qtrssince 2019-Q2
Increased
53
MASIMASIDelisted

MASIMO CORP

594,956$136.6M2.1%——
9 qtrssince 2019-Q1
Increased
64

10X GENOMICS INC

711,515$128.8M2.0%$89.77+101.63%
7 qtrssince 2019-Q3
Increased
56

CERNER CORP

1.8M$127.6M2.0%——
4 qtrssince 2020-Q2
Increased
50
AXNXAXNXDelisted

AXONICS INC

1.9M$112.8M1.8%——
9 qtrssince 2019-Q1
Unchanged
0

QUIDEL CORP

878,533$112.4M1.8%$127.930.00%
1 qtr
New
69

ARVINAS INC

1.6M$107.3M1.7%$84.93-22.17%
2 qtrssince 2020-Q4
Decreased
0

GLOBUS MED INC

1.7M$103M1.6%$65.16-5.35%
2 qtrssince 2020-Q4
Increased
48

IMMUNOVANT INC

6.4M$102M1.6%$22.20-27.75%
6 qtrssince 2019-Q4
Decreased
0
$6.4B
AUM
111
Positions
Q1 2021
Filing
HI score · 2.5/5
Quarterly 13F Value Change
+58%Q4'19$2.7B-12%Q1'20$2.3B+53%Q2'20$3.6B+17%Q3'20$4.2B+44%Q4'20$6B+7%Q1'21$6.4B
Activity profile
$ moved · Q1'21
New32%Increased28%Decreased32%Exited8%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.6 quarters
<1Q15%1-4Q41%1-2Y23%2Y+20%

RTW INVESTMENTS, LP manages $6.4B across 111 positions as of Q1 2021. Top holdings: RCKT (10.9%), SPY (5.9%), VCEL (3.9%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q1 2021 Summary

Active quarter - 18 new positions, 9 exits, 32 increased. Top move: SPY (NEW, conviction 96). Portfolio: $6.4B across 111 positions.

Top holdings by portfolio weight

Total AUM$6B
RCKT10.89%
SPY5.85%
VCEL3.92%
PTCT3.91%
ALNY3.71%
MRTX3.57%
DRNA2.98%
ILMN2.89%
NTRA2.71%
DMTKQ2.47%
Other2.26%

Portfolio allocation by GICS sector

Sectors2
Healthcare71.59%
Unknown28.41%

Behavioral investing profile

Checking access…
Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L58
Conviction44
Concentration72
Checking access…

Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
7Q
RDNTRDNTRADNET INC
Q4 2024 → Q2 2026+3M shares+$173.4M
6Q
CMPSCMPSCOMPASS PATHWAYS PLC
Q1 2025 → Q2 2026+7.6M shares+$139.7M
6Q
IMTXIMTXIMMATICS N.V
Q1 2025 → Q2 2026+6.4M shares+$84.6M
Checking access…

Famous Investors' Portfolios

What the most-followed managers hold, and what they bought and sold each quarter.

Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

Analytics tracking helps us improve the product. Essential functions stay on either way. How analytics data is used