AMYLYX PHARMACEUTICALS INC

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AMLX·03237H101·US·Common Stock·Healthcare - Drug Manufacturers - Specialty & Generic-13D/G

AMLX (AMYLYX PHARMACEUTICALS INC) is held by 117 institutional investors as of Q2 2026. Largest holders: FMR LLC ($300.4M), BlackRock, Inc. ($158.5M), Jupiter Topco LLC ($94M). Net institutional sentiment: Bullish.

117

Holders

(9 Elite)

$1.3B

Total Value

68% (111)

Consensus

75 buying - 36 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)40

Insider (Form 4)81

Activist (13D/13G)42

Congressional (STOCK Act)26

Holder Quality

81

★★★★★

Elite

77

★★★★

Strong

89

★★★

Solid

47

★★

Below

46

★

Weak

Held by 117 funds

9 elite

Who's Trading

Source dates: Price Oct 13, 2026 · Insiders Oct 7, 2026 · Activists May 15, 2026 · Congress none

InsiderMJMILNE GEORGE M JRSell $831KOct 5, 2026

InsiderKBKlee Justin B.Sell $48KSep 10, 2026

InsiderBLBedrosian Camille LSell $69KSep 10, 2026

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Top Holders

Top Holders (117)History

AllNewIncreasedHeldDecreasedExitedFirst report

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	16.7M(+0.6%)	$300.4M	0.0%	+123.69%	31
BlackRock, Inc.	Decreased	8.8M(-0.0%)	$158.5M	0.0%	+226.64%	0
JTJupiter Topco LLC	First report	5.2M	$94M	0.0%	+53.01%	0
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	4.2M(+2.0%)	$75.9M	0.0%	+93.72%	30
MORGAN STANLEY	Increased	3.1M(+43.9%)	$56.2M	0.0%	+101.44%	40
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	3M(+1.7%)	$54.5M	0.3%	+152.36%	36
FRANKLIN TEMPLETON INC	Increased	3M(+30.4%)	$53M	0.0%	+94.20%	37
GOLDMAN SACHS GROUP INC	Increased	2.9M(+8.8%)	$51.3M	0.0%	+101.03%	32
STATE STREET CORP	Increased	2.6M(+10.2%)	$46.8M	0.0%	+131.61%	32
GEODE CAPITAL MANAGEMENT, LLC	Increased	2.3M(+5.6%)	$41.9M	0.0%	+137.39%	31
JPMORGAN CHASE & CO	Increased	1.9M(+1067.2%)	$34.9M	0.0%	+57.96%	47
AGADAGE CAPITAL PARTNERS GP, L.L.C.	Decreased	1.9M(-46.6%)	$34.1M	0.0%	+313.36%	0
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	1.1M(+12.4%)	$19.1M	0.0%	+89.08%	32
AIAlyeska Investment Group, L.P.	New	1.1M	$18.9M	0.0%	+53.01%	39
DIMENSIONAL FUND ADVISORS LP	Decreased	902,463(-0.1%)	$16.2M	0.0%	+173.59%	0
Woodline Partners LP	Increased	846,387(+0.1%)	$15.2M	0.0%	+647.59%	28
NORTHERN TRUST CORP	Increased	831,740(+6.7%)	$14.9M	0.0%	+188.62%	30
BANK OF AMERICA CORP /DE/	Decreased	821,841(-38.2%)	$14.8M	0.0%	+186.52%	0
Aberdeen Group plc	New	737,670	$13.2M	0.0%	+53.01%	39
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	725,030(+1.2%)	$13M	0.0%	+115.36%	28

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer