AMYLYX PHARMACEUTICALS INC (AMLX) is held by 97 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is FMR LLC as of Q1 2026.

Are institutions buying or selling AMLX?

In Q1 2026, 58 institutions opened or increased positions in AMYLYX PHARMACEUTICALS INC while 47 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on AMLX?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for AMYLYX PHARMACEUTICALS INC.

How many hedge funds hold AMLX?

97 institutional investors report holding AMYLYX PHARMACEUTICALS INC (AMLX) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into AMLX?

As of Q1 2026, tracked institutions in AMYLYX PHARMACEUTICALS INC show 58 buyers versus 47 sellers — net inflows.

AMYLYX PHARMACEUTICALS INC

AMLX·03237H101·US·Common Stock·Healthcare - Drug Manufacturers - Specialty & Generic-13D/G

Holders

Avg rating(20 Elite)

$959.7M

Total Value

55% (112)

Fund Consensus

58 buying - 47 selling

Smart Money Verdict

View all

Held by 97 funds

20 elite

Who's Trading

InsiderMGMazzariello GinaSell $264KJul 10, 2026

InsiderMGMazzariello GinaSell $275KJul 9, 2026

InsiderFKFirestone KarenBuy $51KMay 21, 2026

ActivistPAPerceptive Advisors LLC7.5%May 15, 2026

Activist

The Vanguard Group0.0%Mar 26, 2026

InsiderCBCohen Joshua BSell $424KMar 2, 2026

InsiderKBKlee Justin B.Sell $424KMar 2, 2026

InsiderBLBedrosian Camille LSell $94KMar 2, 2026

InsiderFMFRATES JAMES MSell $115KMar 2, 2026

InsiderMGMazzariello GinaSell $99KMar 2, 2026

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	16.6M(+0.7%)	$231.2M	0.0%	+45.06%	31
BlackRock, Inc.	Decreased	8.8M(-2.5%)	$122.7M	0.0%	+111.22%	0
Janus Henderson Group Ltd.	Increased	5M(+11.7%)	$69.3M	0.0%	+29.75%	33
VAVANGUARD CAPITAL MANAGEMENT LLC	New	4.1M	$57.6M	0.0%	+25.94%	41
AGADAGE CAPITAL PARTNERS GP, L.L.C.	Increased	3.6M(+28.2%)	$49.5M	0.1%	+165.46%	37
DRIEHAUS CAPITAL MANAGEMENT LLC	Decreased	3M(-3.9%)	$41.5M	0.3%	+64.98%	0
GOLDMAN SACHS GROUP INC	Increased	2.6M(+0.5%)	$36.5M	0.0%	+102.91%	29
STATE STREET CORP	Increased	2.4M(+14.2%)	$32.8M	0.0%	+64.65%	33
FRANKLIN RESOURCES INC	Increased	2.3M(+88.5%)	$31.4M	0.0%	+36.79%	45
GEODE CAPITAL MANAGEMENT, LLC	Increased	2.2M(+2.1%)	$30.7M	0.0%	+53.74%	29
MORGAN STANLEY	Decreased	2.2M(-7.8%)	$30.2M	0.0%	+51.29%	0
BANK OF AMERICA CORP /DE/	Decreased	1.3M(-0.4%)	$18.5M	0.0%	+89.51%	0
$DEUTSCHE BANK AG\$ DEUTSCHE BANK AG\	Decreased	1.3M(-4.9%)	$17.6M	0.0%	+21.50%	0
BALYASNY ASSET MANAGEMENT L.P.	Increased	1.1M(+28.9%)	$15.4M	0.0%	+20.70%	35
BARCLAYS PLC	Increased	971,854(+229.2%)	$13.5M	0.0%	+30.50%	45
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	944,781	$13.1M	0.0%	+25.94%	39
DIMENSIONAL FUND ADVISORS LP	Increased	903,192(+17.1%)	$12.5M	0.0%	+76.92%	33
Connor, Clark & Lunn Investment Management Ltd.	Decreased	868,325(-13.5%)	$12.1M	0.0%	+201.81%	0
Woodline Partners LP	Increased	845,800(+0.1%)	$11.8M	0.0%	+384.72%	28
NORTHERN TRUST CORP	Decreased	779,908(-16.8%)	$10.8M	0.0%	+95.19%	0