Apogee Therapeutics, Inc. (APGE) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling APGE?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Apogee Therapeutics, Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on APGE?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Apogee Therapeutics, Inc..

Is institutional money flowing into APGE?

119 institutional investors hold Apogee Therapeutics, Inc. (APGE). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about APGE?

Track institutional sentiment and conviction scores for Apogee Therapeutics, Inc. (APGE) including Smart Money Verdict and position changes on HoldingsIntel.

Apogee Therapeutics, Inc.

APGE·03770N101·US·equity·Healthcare - Biotechnology-Activist

APGE (Apogee Therapeutics, Inc.) is held by 119 institutional investors as of Q4 2025. Largest holders: FMR LLC ($620.8M), WELLINGTON MANAGEMENT GROUP LLP ($358.3M), BlackRock, Inc. ($285.6M). Net institutional sentiment: Bullish.

119

Holders

Avg rating(7 Elite)

$3.3B

Total Value

73% (124)

Fund Consensus

85 buying - 32 selling

Smart Money VerdictView all

46Weak MomentumSplit Signals

Get 5 free verdicts/month - sign up in 10 seconds

See how APGE's score breaks down across 4 SEC sources

Held by 119 funds

7 elite

Who's Trading

InsiderHENDERSON MICHAEL THOMASSell $1.5MApr 8, 2026

Activist

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	8.2M(+18.9%)	$620.8M	0.0%	+38.14%	37
WELLINGTON MANAGEMENT GROUP LLP	Increased	4.7M(+0.5%)	$358.3M	0.1%	+59.52%	31
BlackRock, Inc.	Increased	3.8M(+40.9%)	$285.6M	0.0%	+28.01%	41
VANGUARD GROUP INC	Increased	2.9M(+27.3%)	$215.7M	0.0%	+12.68%	38
RTW INVESTMENTS, LP	Unchanged	2.7M	$204.7M	2.1%	+141.73%	0
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	2.2M(+1.2%)	$164.8M	1.1%	+65.83%	48
JANUS HENDERSON GROUP PLC	Increased	2.1M(+324.4%)	$155.7M	0.1%	-0.41%	49
STATE STREET CORP	Increased	1.7M(+2.1%)	$127.6M	0.0%	+35.85%	31
JPMORGAN CHASE & CO	Increased	1.4M(+20.7%)	$103.6M	0.0%	+47.42%	36
ALLIANCEBERNSTEIN L.P.	Decreased	1.1M(-22.9%)	$82.5M	0.0%	+26.43%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.1M(+18.7%)	$80M	0.0%	+44.77%	35
UBS Group AG	Increased	974,826(+21.9%)	$73.6M	0.0%	+46.14%	36
MERCER GLOBAL ADVISORS INC /ADV	Decreased	890,665(-8.2%)	$67.2M	0.1%	+64.81%	0
MORGAN STANLEY	Increased	890,264(+91.5%)	$67.2M	0.0%	+20.35%	47
BANK OF AMERICA CORP /DE/	Increased	793,695(+101.5%)	$59.9M	0.0%	+16.74%	48
CITADEL ADVISORS LLC	Decreased	766,981(-34.4%)	$57.9M	0.0%	+65.43%	0
JENNISON ASSOCIATES LLC	New	578,627	$43.7M	0.0%	-9.58%	40
GOLDMAN SACHS GROUP INC	Decreased	565,410(-5.7%)	$42.7M	0.0%	+55.91%	0
Polar Capital Holdings Plc	Decreased	503,539(-3.9%)	$38M	0.1%	+72.43%	0
Avoro Capital Advisors LLC	New	500,000	$37.7M	0.4%	-9.58%	49
FRONTIER CAPITAL MANAGEMENT CO LLC	Increased	480,453(+28.3%)	$36.3M	0.4%	+28.39%	43
FRANKLIN RESOURCES INC	Decreased	451,002(-38.3%)	$34M	0.0%	+208.56%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	381,362(+19.2%)	$28.8M	0.0%	+48.79%	34
NORTHERN TRUST CORP	Increased	327,376(+15.1%)	$24.7M	0.0%	+47.19%	33
Pictet Asset Management Holding SA	New	312,883	$23.6M	0.0%	-9.58%	40
LOOMIS SAYLES & CO L P	New	255,439	$19.3M	0.0%	-9.58%	39
ADAGE CAPITAL PARTNERS GP, L.L.C.	Increased	240,000(+2.1%)	$18.1M	0.0%	+59.55%	29
Woodline Partners LP	Increased	210,466(+267.2%)	$15.9M	0.1%	+0.53%	45
Candriam S.C.A.	Increased	191,318(+51.7%)	$14.4M	0.1%	+31.52%	39
MILLENNIUM MANAGEMENT LLC	Decreased	140,727(-67.3%)	$10.6M	0.0%	+57.01%	0
BARCLAYS PLC	Decreased	133,193(-79.3%)	$10.1M	0.0%	+40.26%	0
TD ASSET MANAGEMENT INC	Increased	129,290(+55.3%)	$9.8M	0.0%	+29.35%	39
FEDERATED HERMES, INC.	New	127,931	$9.7M	0.0%	-9.58%	38
Universal- Beteiligungs- und Servicegesellschaft mbH	Decreased	127,629(-2.9%)	$9.6M	0.0%	+54.16%	0
Capital World Investors	Unchanged	127,618	$9.6M	0.0%	+53.45%	0
AMERIPRISE FINANCIAL INC	Increased	122,900(+19.1%)	$9.3M	0.0%	+46.25%	33
Nuveen, LLC	Increased	121,050(+45.3%)	$9.1M	0.0%	+34.41%	37
Bank of New York Mellon Corp	Increased	118,084(+9.8%)	$8.9M	0.0%	+50.58%	30
VICTORY CAPITAL MANAGEMENT INC	Decreased	108,267(-50.2%)	$8.2M	0.0%	+27.59%	0
SCHRODER INVESTMENT MANAGEMENT GROUP	Decreased	105,000(-51.4%)	$8M	0.0%	+71.05%	0
TWO SIGMA INVESTMENTS, LP	Decreased	105,241(-14.0%)	$7.9M	0.0%	+55.49%	0
Neuberger Berman Group LLC	New	99,648	$7.5M	0.0%	-9.58%	38
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Increased	80,832(+27.9%)	$6.1M	0.0%	+41.78%	34
DEUTSCHE BANK AG\	Increased	79,361(+3.7%)	$6M	0.0%	+56.09%	28
NOMURA HOLDINGS INC	New	76,898	$5.8M	0.0%	-9.58%	38
Invesco Ltd.	Increased	70,687(+142.6%)	$5.3M	0.0%	+2.66%	44
D. E. Shaw & Co., Inc.	Decreased	63,250(-37.1%)	$4.8M	0.0%	+58.57%	0
Swiss National Bank	Increased	62,900(+44.9%)	$4.7M	0.0%	+39.49%	36
SIMPLEX TRADING, LLC	New	62,799	$4.7M	0.0%	-9.58%	37
PRUDENTIAL FINANCIAL INC	Increased	54,300(+322.2%)	$4.1M	0.0%	+0.17%	43
Blackstone Inc.	Decreased	51,827(-72.8%)	$3.9M	0.0%	+110.05%	0
MARSHALL WACE, LLP	Increased	50,744(+622.1%)	$3.8M	0.0%	-3.92%	43
Russell Investments Group, Ltd.	Increased	49,999(+14.5%)	$3.8M	0.0%	+49.22%	30
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	49,805(+59.8%)	$3.8M	0.0%	+27.14%	38
Rafferty Asset Management, LLC	Decreased	48,619(-26.1%)	$3.7M	0.0%	+26.29%	0
RHUMBLINE ADVISERS	Decreased	45,971(-3.8%)	$3.5M	0.0%	+53.15%	0
ALPS ADVISORS INC	Increased	44,922(+99.6%)	$3.4M	0.0%	+18.73%	43
WELLS FARGO & COMPANY/MN	Increased	42,499(+93.3%)	$3.2M	0.0%	+7.48%	42
BANQUE PICTET & CIE SA	New	41,800	$3.2M	0.0%	-9.58%	37
Aberdeen Group plc	Decreased	36,103(-34.1%)	$2.7M	0.0%	+71.98%	0
COMERICA BANK	Increased	35,872(+0.9%)	$2.7M	0.0%	+38.80%	26
Legal & General Group Plc	Increased	32,856(+18.8%)	$2.5M	0.0%	+37.55%	31
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	30,758(+43.8%)	$2.3M	0.0%	+42.94%	35
TUDOR INVESTMENT CORP ET AL	New	30,039	$2.3M	0.0%	-9.58%	36
Schonfeld Strategic Advisors LLC	New	29,145	$2.2M	0.0%	-9.58%	36
Erste Asset Management GmbH	Unchanged	24,000	$1.8M	0.0%	+53.45%	0
NEW YORK STATE COMMON RETIREMENT FUND	Increased	22,484(+127.4%)	$1.7M	0.0%	+7.10%	41
MetLife Investment Management, LLC	Increased	21,311(+10.8%)	$1.6M	0.0%	+45.64%	28
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	20,709(+11.5%)	$1.6M	0.0%	+58.26%	29
STATE OF WISCONSIN INVESTMENT BOARD	Increased	20,313(+150.9%)	$1.5M	0.0%	+13.42%	41
XTX Topco Ltd	Increased	19,026(+225.1%)	$1.4M	0.0%	+5.01%	41
VOYA INVESTMENT MANAGEMENT LLC	Increased	18,492(+97.3%)	$1.4M	0.0%	+8.90%	41
SEI INVESTMENTS CO	New	16,329	$1.2M	0.0%	-9.58%	35
Qube Research & Technologies Ltd	New	14,283	$1.1M	0.0%	-9.58%	35
INTECH INVESTMENT MANAGEMENT LLC	Unchanged	13,701	$1M	0.0%	+42.88%	0
Verition Fund Management LLC	Decreased	12,700(-74.4%)	$958,596	0.0%	+71.98%	0
Connor, Clark & Lunn Investment Management Ltd.	New	12,689	$957,766	0.0%	-9.58%	35
JANE STREET GROUP, LLC	Decreased	12,192(-84.3%)	$920,252	0.0%	+69.82%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Increased	11,879(+32.6%)	$896,627	0.0%	+29.68%	32
LMR Partners LLP	Decreased	11,461(-39.5%)	$865,076	0.0%	+71.98%	0
Man Group plc	New	11,163	$842,583	0.0%	-9.58%	34
State of New Jersey Common Pension Fund D	New	10,879	$821,147	0.0%	-9.58%	34
Police & Firemen's Retirement System of New Jersey	Increased	10,330(+10.6%)	$779,708	0.0%	+46.71%	27
BNP PARIBAS FINANCIAL MARKETS	Decreased	9,965(-73.9%)	$752,158	0.0%	+70.15%	0
ProShare Advisors LLC	Increased	9,464(+30.7%)	$714,344	0.0%	+7.06%	31
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	9,350	$705,738	0.0%	+74.08%	0
Mariner, LLC	Increased	9,101(+54.9%)	$686,917	0.0%	+24.88%	35
Creative Planning	Increased	8,904(+21.2%)	$672,074	0.0%	+39.68%	29
CITIGROUP INC	Increased	8,882(+36.6%)	$670,413	0.0%	+30.07%	32
Arizona State Retirement System	Increased	8,763(+32.7%)	$661,431	0.0%	+5.05%	31
GLENMEDE TRUST CO NA	Increased	8,512(+43.9%)	$642,485	0.0%	-0.35%	33
COMMONWEALTH EQUITY SERVICES, LLC	Increased	7,151(+2.2%)	$539,760	0.0%	+55.45%	25
KLP KAPITALFORVALTNING AS	Increased	6,800(+65.8%)	$513,264	0.0%	+20.18%	35
DnB Asset Management AS	New	5,775	$435,897	0.0%	-9.58%	33
Allspring Global Investments Holdings, LLC	New	5,435	$411,865	0.0%	-9.58%	33
STIFEL FINANCIAL CORP	Increased	5,214(+3.5%)	$393,553	0.0%	+66.93%	25
TEACHER RETIREMENT SYSTEM OF TEXAS	Decreased	4,705(-14.3%)	$355,134	0.0%	+26.15%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	4,634(-72.2%)	$349,774	0.0%	+48.62%	0
FIRST TRUST ADVISORS LP	New	3,418	$257,990	0.0%	-9.58%	32
STRS OHIO	New	3,300	$249,084	0.0%	-9.58%	32
XPONANCE LLC	New	3,015	$227,572	0.0%	-9.58%	32
Vident Advisory, LLC	New	2,891	$218,213	0.0%	-9.58%	32
Mirae Asset Global Investments Co., Ltd.	Increased	2,665(+49.5%)	$201,154	0.0%	+27.68%	32
Ensign Peak Advisors, Inc	New	2,250	$169,830	0.0%	-9.58%	31
PRICE T ROWE ASSOCIATES INC /MD/	Increased	1.2M(+64.8%)	$93,380	0.0%	+27.32%	32
ROYAL BANK OF CANADA	Decreased	1,138(-71.7%)	$85,000	0.0%	+71.59%	0
GROUP ONE TRADING LLC	New	1,057	$79,782	0.0%	-9.58%	30
OSAIC HOLDINGS, INC.	Increased	959(+74.7%)	$72,385	0.0%	+22.10%	32
NISA INVESTMENT ADVISORS, LLC	Decreased	701(-7.2%)	$52,911	0.0%	+57.38%	0
LOS ANGELES CAPITAL MANAGEMENT LLC	New	490	$27,459	0.0%	-9.58%	27
US BANCORP \DE\	Decreased	346(-13.5%)	$26,116	0.0%	+59.25%	0
Rockefeller Capital Management L.P.	New	337	$25,437	0.0%	-9.58%	29
Optiver Holding B.V.	Decreased	156(-42.2%)	$11,775	0.0%	+71.98%	0
JONES FINANCIAL COMPANIES LLLP	Unchanged	98	$7,397	0.0%	+71.98%	0
PNC FINANCIAL SERVICES GROUP, INC.	Increased	82(+1.2%)	$6,189	0.0%	+59.11%	11
Farther Finance Advisors, LLC	Increased	50(+85.2%)	$3,774	0.0%	+21.67%	15
BNP Paribas Asset Management Holding S.A.	Increased	39,846(+196x)	$3,007	0.0%	-9.39%	21
Allworth Financial LP	Unchanged	1	$76	0.0%	+57.91%	0
BALYASNY ASSET MANAGEMENT L.P.	Exited	0(-100.0%)	$2.9M	0.0%	+85.78%	0
Federation des caisses Desjardins du Quebec	Exited	0(-100.0%)	$397	0.0%	+69.71%	0
Caption Management, LLC	Exited	0(-100.0%)	$190,704	0.0%	+78.26%	0
Jefferies Financial Group Inc.	Exited	0(-100.0%)	$22.6M	0.0%	+71.37%	0
ExodusPoint Capital Management, LP	Exited	0(-100.0%)	$1.5M	0.0%	+90.21%	0
NOMURA ASSET MANAGEMENT CO LTD	New	0	$0	0.0%	-9.58%	17

Apogee Therapeutics, Inc.

Continue exploring