CASTLE BIOSCIENCES INC

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CSTL·14843C105·US·equity·Healthcare - Diagnostics & Research-13D/G

CSTL (CASTLE BIOSCIENCES INC) is held by 101 institutional investors as of Q1 2026. Largest holders: BlackRock, Inc. ($73.2M), RTW INVESTMENTS, LP ($67.7M), PRINCIPAL FINANCIAL GROUP INC ($43.5M). Net institutional sentiment: Mixed.

101

Holders

Avg rating(11 Elite)

$470.4M

Total Value

51% (117)

Fund Consensus

56 buying - 54 selling

Smart Money Verdict

View all

33Negative MomentumStrong Convergence

Institutional (13F)48

Insider (Form 4)0

Activist (13D/13G)50

Congressional (STOCK Act)

No data

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See how CSTL's score breaks down across 4 SEC sources

Holder Quality

11

★★★★★

Elite

34

★★★★

Strong

34

★★★

Solid

32

★★

Below

6

★

Weak

Held by 101 funds

11 elite

Who's Trading

ActivistPOPortolan Capital Management, LLC4.5%May 15, 2026

ActivistRTW Investments, LP9.3%May 15, 2026

InsiderMJMAETZOLD DEREK JSell $26KMay 7, 2026

InsiderMJMAETZOLD DEREK JSell $4KMay 7, 2026

InsiderMJMAETZOLD DEREK JSell $22KMay 7, 2026

InsiderMJMAETZOLD DEREK JSell $4KMay 7, 2026

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13F: Mar 31, 2026Insider & Congress: Updated regularly

Positions (101)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Decreased	3M(-3.9%)	$73.2M	0.0%	-26.83%	0
RTW INVESTMENTS, LP	Increased	2.8M(+30.4%)	$67.7M	0.7%	-47.69%	53
PRINCIPAL FINANCIAL GROUP INC	Decreased	1.8M(-2.1%)	$43.5M	0.0%	-25.49%	0
DIMENSIONAL FUND ADVISORS LP	Decreased	1M(-9.1%)	$25.5M	0.0%	-12.92%	0
Allianz Asset Management GmbH	Increased	811,324(+30.4%)	$19.9M	0.0%	-20.85%	36
STATE STREET CORP	Increased	769,079(+4.4%)	$18.9M	0.0%	-16.24%	30
GEODE CAPITAL MANAGEMENT, LLC	Increased	728,100(+1.8%)	$17.9M	0.0%	-49.35%	29
Qube Research & Technologies Ltd	Increased	559,583(+137.6%)	$13.7M	0.0%	-28.81%	45
RENAISSANCE TECHNOLOGIES LLC	Increased	532,800(+8.1%)	$13.1M	0.0%	-21.45%	30
Nuveen, LLC	Decreased	522,127(-0.5%)	$12.8M	0.0%	-4.79%	0
WASATCH ADVISORS LP	Decreased	455,036(-15.3%)	$11.2M	0.1%	-56.24%	0
MORGAN STANLEY	Increased	428,934(+110.7%)	$10.5M	0.0%	-25.25%	45
Connor, Clark & Lunn Investment Management Ltd.	Decreased	377,082(-2.9%)	$9.3M	0.0%	-24.33%	0
MILLENNIUM MANAGEMENT LLC	Increased	353,319(+14.4%)	$8.7M	0.0%	-21.20%	31
GOLDMAN SACHS GROUP INC	Increased	341,171(+18.8%)	$8.4M	0.0%	-22.05%	32
SCHRODER INVESTMENT MANAGEMENT GROUP	Decreased	298,941(-39.3%)	$7M	0.0%	-4.22%	0
NORTHERN TRUST CORP	Increased	273,101(+4.1%)	$6.7M	0.0%	-47.16%	28
SILVERCREST ASSET MANAGEMENT GROUP LLC	Increased	268,535(+31.0%)	$6.6M	0.0%	-25.05%	35
TWO SIGMA INVESTMENTS, LP	Increased	248,840(+196.0%)	$6.1M	0.0%	-35.23%	44
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	241,880(-0.3%)	$5.9M	0.0%	-54.45%	0

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High Conviction Moves-Signal Convergence-Fund Consensus-Double-Down Signals

Data sourced from four SEC data sources: 13F, Form 4, 13D/13G, and STOCK Act. Not financial advice. Full disclaimer