CASTLE BIOSCIENCES INC (CSTL) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling CSTL?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for CASTLE BIOSCIENCES INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on CSTL?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for CASTLE BIOSCIENCES INC.

Is institutional money flowing into CSTL?

110 institutional investors hold CASTLE BIOSCIENCES INC (CSTL). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about CSTL?

Track institutional sentiment and conviction scores for CASTLE BIOSCIENCES INC (CSTL) including Smart Money Verdict and position changes on HoldingsIntel.

CASTLE BIOSCIENCES INC

CSTL·14843C105·US·equity·Healthcare - Diagnostics & Research-13D/G

CSTL (CASTLE BIOSCIENCES INC) is held by 110 institutional investors as of Q4 2025. Largest holders: BlackRock, Inc. ($120.8M), VANGUARD GROUP INC ($85.6M), RTW INVESTMENTS, LP ($82.3M). Net institutional sentiment: Mixed.

110

Holders

Avg rating(8 Elite)

$811.8M

Total Value

57% (118)

Fund Consensus

60 buying - 46 selling

Smart Money Verdict- Q4 2025View all

41Weak MomentumSplit Signals

Held by 110 funds

8 elite

Who's Trading

InsiderMAETZOLD DEREK JSell $156KApr 6, 2026

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Decreased	3.1M(-2.6%)	$120.8M	0.0%	+5.46%	0
VANGUARD GROUP INC	Increased	2.2M(+1.3%)	$85.6M	0.0%	+3.03%	30
RTW INVESTMENTS, LP	New	2.1M	$82.3M	0.8%	-29.87%	58
PRINCIPAL FINANCIAL GROUP INC	Increased	1.8M(+0.7%)	$70.3M	0.0%	+7.38%	30
DIMENSIONAL FUND ADVISORS LP	Decreased	1.1M(-22.4%)	$44.5M	0.0%	+25.50%	0
STATE STREET CORP	Increased	736,454(+1.7%)	$28.6M	0.0%	+21.84%	29
GEODE CAPITAL MANAGEMENT, LLC	Increased	714,913(+2.3%)	$27.8M	0.0%	-27.37%	29
Allianz Asset Management GmbH	Decreased	622,299(-4.0%)	$24.2M	0.0%	+19.16%	0
WASATCH ADVISORS LP	Decreased	537,241(-19.7%)	$20.9M	0.1%	-36.93%	0
Nuveen, LLC	Decreased	524,681(-45.2%)	$20.4M	0.0%	+37.21%	0
SCHRODER INVESTMENT MANAGEMENT GROUP	Decreased	492,161(-0.6%)	$19.3M	0.0%	+38.04%	0
RENAISSANCE TECHNOLOGIES LLC	Decreased	493,100(-12.3%)	$19.2M	0.0%	+14.42%	0
Connor, Clark & Lunn Investment Management Ltd.	Increased	388,491(+15.7%)	$15.1M	0.0%	+9.05%	32
CITADEL ADVISORS LLC	Increased	366,356(+46.0%)	$14.3M	0.0%	+3.57%	38
MILLENNIUM MANAGEMENT LLC	Decreased	308,914(-46.3%)	$12M	0.0%	+15.82%	0
GOLDMAN SACHS GROUP INC	Decreased	287,235(-16.8%)	$11.2M	0.0%	+15.00%	0
BANK OF AMERICA CORP /DE/	Decreased	263,019(-16.6%)	$10.2M	0.0%	+3.89%	0
NORTHERN TRUST CORP	Decreased	262,243(-7.1%)	$10.2M	0.0%	-24.60%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	242,535(+1.8%)	$9.4M	0.0%	-34.36%	28
Qube Research & Technologies Ltd	Increased	235,518(+6.6%)	$9.2M	0.0%	+6.40%	29
NEW YORK STATE COMMON RETIREMENT FUND	Increased	233,046(+1.3%)	$9.1M	0.0%	-14.14%	28
WELLINGTON MANAGEMENT GROUP LLP	New	218,560	$8.5M	0.0%	-29.87%	38
SILVERCREST ASSET MANAGEMENT GROUP LLC	Decreased	205,002(-44.3%)	$8M	0.1%	+10.77%	0
MORGAN STANLEY	Decreased	203,577(-24.5%)	$7.9M	0.0%	+17.82%	0
JANE STREET GROUP, LLC	Increased	168,646(+637.0%)	$6.6M	0.0%	-25.51%	44
TUDOR INVESTMENT CORP ET AL	Increased	167,178(+95.7%)	$6.5M	0.0%	-9.36%	43
D. E. Shaw & Co., Inc.	Increased	159,709(+72.5%)	$6.2M	0.0%	-7.93%	41
Allspring Global Investments Holdings, LLC	Increased	159,171(+1.7%)	$6.1M	0.0%	+35.17%	28
BNP PARIBAS FINANCIAL MARKETS	Increased	150,011(+7.2%)	$5.8M	0.0%	+14.53%	29
UBS Group AG	Decreased	141,873(-51.3%)	$5.5M	0.0%	+30.32%	0
Invesco Ltd.	Increased	135,461(+142.6%)	$5.3M	0.0%	-24.62%	44
Empowered Funds, LLC	Increased	121,920(+24.2%)	$4.7M	0.0%	+10.33%	33
Point72 Asset Management, L.P.	Decreased	119,458(-64.5%)	$4.6M	0.0%	+23.30%	0
JPMORGAN CHASE & CO	Increased	90,032(+224.1%)	$3.5M	0.0%	-22.02%	43
Bank of New York Mellon Corp	Decreased	86,984(-7.5%)	$3.4M	0.0%	-38.57%	0
TWO SIGMA INVESTMENTS, LP	Increased	84,066(+227.1%)	$3.3M	0.0%	-17.43%	43
FRANKLIN RESOURCES INC	Decreased	80,603(-19.2%)	$3.1M	0.0%	+16.71%	0
AMERICAN CENTURY COMPANIES INC	Decreased	77,768(-5.8%)	$3M	0.0%	+25.86%	0
Orion Porfolio Solutions, LLC	Decreased	74,653(-2.2%)	$2.9M	0.0%	-4.85%	0
BARCLAYS PLC	Decreased	72,149(-1.3%)	$2.8M	0.0%	+21.22%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	69,628(+21.2%)	$2.7M	0.0%	-1.73%	31
Trexquant Investment LP	Decreased	64,605(-63.8%)	$2.5M	0.0%	+14.94%	0
AQR CAPITAL MANAGEMENT LLC	Increased	63,881(+25.6%)	$2.5M	0.0%	+11.38%	32
ENVESTNET ASSET MANAGEMENT INC	Decreased	61,966(-7.4%)	$2.4M	0.0%	-17.27%	0
Swiss National Bank	Increased	57,300(+2.3%)	$2.2M	0.0%	-31.56%	27
Squarepoint Ops LLC	New	55,118	$2.1M	0.0%	-29.87%	36
PANAGORA ASSET MANAGEMENT INC	Increased	45,995(+115.0%)	$1.8M	0.0%	-12.27%	42
FMR LLC	Increased	42,286(+48.1%)	$1.6M	0.0%	+2.53%	35
SEI INVESTMENTS CO	Increased	39,727(+48.4%)	$1.5M	0.0%	-5.74%	35
RHUMBLINE ADVISERS	Decreased	38,468(-12.1%)	$1.5M	0.0%	-16.82%	0
MACKENZIE FINANCIAL CORP	Increased	37,317(+54.2%)	$1.5M	0.0%	-8.35%	36
OSAIC HOLDINGS, INC.	Increased	36,404(+8822.5%)	$1.4M	0.0%	-29.51%	41
AMERIPRISE FINANCIAL INC	Decreased	35,368(-86.2%)	$1.4M	0.0%	+24.56%	0
WELLS FARGO & COMPANY/MN	Increased	34,212(+42.7%)	$1.3M	0.0%	+3.94%	34
CITIGROUP INC	Increased	32,422(+662.9%)	$1.3M	0.0%	-26.19%	41
TWO SIGMA ADVISERS, LP	Increased	29,899(+202.0%)	$1.2M	0.0%	-17.12%	41
Legal & General Group Plc	Decreased	29,735(-14.8%)	$1.2M	0.0%	+0.21%	0
Universal- Beteiligungs- und Servicegesellschaft mbH	Decreased	29,357(-1.8%)	$1.1M	0.0%	+36.07%	0
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	27,725(+12.6%)	$1.1M	0.0%	-36.16%	28
ALLIANCEBERNSTEIN L.P.	Decreased	25,270(-24.3%)	$983,003	0.0%	-1.20%	0
TRUIST FINANCIAL CORP	Increased	23,628(+1.1%)	$919,129	0.0%	+41.61%	25
Engineers Gate Manager LP	Decreased	22,949(-50.6%)	$892,716	0.0%	+29.58%	0
DEUTSCHE BANK AG\	Increased	22,384(+34.5%)	$870,738	0.0%	+1.23%	32
XTX Topco Ltd	New	22,125	$860,663	0.0%	-29.87%	34
Schonfeld Strategic Advisors LLC	Decreased	21,476(-75.5%)	$835,415	0.0%	+33.51%	0
HSBC HOLDINGS PLC	Decreased	19,486(-41.4%)	$760,344	0.0%	+28.90%	0
Verition Fund Management LLC	Increased	16,811(+7.5%)	$653,948	0.0%	+19.40%	26
Creative Planning	Decreased	16,141(-0.8%)	$627,885	0.0%	+8.76%	0
MetLife Investment Management, LLC	Unchanged	15,881	$617,771	0.0%	-31.24%	0
JANUS HENDERSON GROUP PLC	Increased	15,037(+64.6%)	$585,014	0.0%	-4.97%	36
LOS ANGELES CAPITAL MANAGEMENT LLC	Decreased	23,631(-2.0%)	$572,106	0.0%	+23.30%	0
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Decreased	13,223(-0.4%)	$514,375	0.0%	+23.48%	0
STRS OHIO	Increased	12,600(+28.6%)	$490,140	0.0%	-1.04%	30
Zurcher Kantonalbank (Zurich Cantonalbank)	Decreased	11,810(-3.3%)	$459,409	0.0%	-14.27%	0
INTECH INVESTMENT MANAGEMENT LLC	Decreased	11,718(-5.4%)	$455,830	0.0%	+8.66%	0
Man Group plc	New	11,585	$450,657	0.0%	-29.87%	33
LPL Financial LLC	Increased	10,877(+15.8%)	$423,115	0.0%	+11.77%	28
Quantinno Capital Management LP	New	9,332	$363,015	0.0%	-29.87%	33
Cetera Investment Advisers	New	8,935	$347,572	0.0%	-29.87%	33
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	8,487(-11.0%)	$330,144	0.0%	+35.48%	0
GLENMEDE TRUST CO NA	New	8,190	$318,591	0.0%	-29.87%	33
Arizona State Retirement System	New	8,071	$313,962	0.0%	-29.87%	32
Police & Firemen's Retirement System of New Jersey	Unchanged	7,829	$304,548	0.0%	+7.84%	0
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	New	7,154	$278,291	0.0%	-29.87%	32
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	New	7,029	$273,428	0.0%	-29.87%	32
COMMONWEALTH EQUITY SERVICES, LLC	New	6,591	$256,390	0.0%	-29.87%	32
ProShare Advisors LLC	New	6,478	$251,994	0.0%	-29.87%	32
CANADA PENSION PLAN INVESTMENT BOARD	Increased	6,300(+162.5%)	$245,070	0.0%	-16.08%	37
KLP KAPITALFORVALTNING AS	Decreased	6,200(-30.3%)	$241,180	0.0%	+11.71%	0
Pictet Asset Management Holding SA	New	5,899	$229,471	0.0%	-29.87%	32
Lido Advisors, LLC	Unchanged	10,036	$228,520	0.0%	+27.75%	0
ASSETMARK, INC	Decreased	5,287(-7.3%)	$205,664	0.0%	+25.45%	0
VOYA INVESTMENT MANAGEMENT LLC	New	5,246	$204,069	0.0%	-29.87%	32
RAYMOND JAMES FINANCIAL INC	New	5,238	$203,759	0.0%	-29.87%	32
Farther Finance Advisors, LLC	Increased	3,337(+139.7%)	$129,809	0.0%	-14.48%	36
Russell Investments Group, Ltd.	Decreased	2,488(-0.8%)	$96,783	0.0%	+36.75%	0
Mirae Asset Global Investments Co., Ltd.	Increased	1,418(+26.5%)	$55,160	0.0%	-0.88%	26
ROYAL BANK OF CANADA	Decreased	865(-3.6%)	$33,000	0.0%	+7.48%	0
FEDERATED HERMES, INC.	New	660	$25,674	0.0%	-29.87%	29
PNC FINANCIAL SERVICES GROUP, INC.	Increased	546(+374.8%)	$21,239	0.0%	-21.79%	21
JONES FINANCIAL COMPANIES LLLP	Increased	515(+1960.0%)	$20,034	0.0%	-28.86%	21
NISA INVESTMENT ADVISORS, LLC	Decreased	281(-22.8%)	$10,931	0.0%	+3.51%	0
HUNTINGTON NATIONAL BANK	Unchanged	139	$5,407	0.0%	+35.31%	0
Rockefeller Capital Management L.P.	New	87	$3,384	0.0%	-29.87%	21
US BANCORP \DE\	Increased	48(+84.6%)	$1,867	0.0%	-8.49%	12
HRT FINANCIAL LP	Increased	47,654(+0.9%)	$1,853	0.0%	+20.29%	11
PRICE T ROWE ASSOCIATES INC /MD/	Increased	34,138(+4.7%)	$1,328	0.0%	+17.79%	12
Allworth Financial LP	Increased	30(+57.9%)	$1,167	0.0%	-2.37%	11
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	New	28	$1,089	0.0%	-29.87%	17
BNP Paribas Asset Management Holding S.A.	Increased	1,839(+298.9%)	$72	0.0%	-20.30%	18
CAPSTONE INVESTMENT ADVISORS, LLC	Exited	0(-100.0%)	$379,735	0.0%	+75.81%	0
GROUP ONE TRADING LLC	Exited	0(-100.0%)	$18,284	0.0%	+75.81%	0
SIMPLEX TRADING, LLC	Exited	0(-100.0%)	$34	0.0%	+75.81%	0
Brevan Howard Capital Management LP	Exited	0(-100.0%)	$435,544	0.0%	+94.33%	0
Optiver Holding B.V.	Exited	0(-100.0%)	$911	0.0%	+75.81%	0
Magnetar Financial LLC	Exited	0(-100.0%)	$235,145	0.0%	+75.81%	0
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	Exited	0(-100.0%)	$815,166	0.0%	+47.45%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Exited	0(-100.0%)	$551,603	0.0%	+72.86%	0

CASTLE BIOSCIENCES INC

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