DENALI THERAPEUTICS INC (DNLI) is held by 138 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is BlackRock, Inc. as of Q1 2026.

Are institutions buying or selling DNLI?

In Q1 2026, 90 institutions opened or increased positions in DENALI THERAPEUTICS INC while 47 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on DNLI?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for DENALI THERAPEUTICS INC.

How many hedge funds hold DNLI?

138 institutional investors report holding DENALI THERAPEUTICS INC (DNLI) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into DNLI?

As of Q1 2026, tracked institutions in DENALI THERAPEUTICS INC show 90 buyers versus 47 sellers — net inflows.

DENALI THERAPEUTICS INC

DNLI·24823R105·US·Common Stock·Healthcare - Biotechnology-13D/G

138

Holders

(12 Elite)

$2.3B

Total Value

66% (137)

Consensus

90 buying - 47 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Held by 138 funds

12 elite

Who's Trading

ActivistTRT. Rowe Price Investment Management, Inc.10.2%Jul 8, 2026

ActivistTRT. Rowe Price Investment Management, Inc.5.4%May 15, 2026

Activist

FMR LLC4.2%May 6, 2026

Activist

The Vanguard Group0.0%Mar 26, 2026

InsiderWJWatts Ryan J.Sell $581KJan 6, 2026

InsiderSOSchuth Alexander O.Sell $284KJan 6, 2026

InsiderHCHo CaroleSell $12KAug 13, 2025

InsiderSOSchuth Alexander O.Sell $40KAug 12, 2025

InsiderHCHo CaroleSell $40KAug 12, 2025

Activist

Wellington Management Group LLP3.9%Aug 12, 2025

View all insider trades View all activist filings

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	13M(+2.5%)	$250.3M	0.0%	+28.36%	32
BAILLIE GIFFORD & CO	Decreased	12.1M(-2.0%)	$231.7M	0.2%	-30.62%	0
Temasek Holdings (Private) Ltd	Unchanged	7M	$134.6M	0.4%	+10.13%	0
STATE STREET CORP	Increased	6.3M(+0.1%)	$120.4M	0.0%	+31.28%	30
VAVANGUARD CAPITAL MANAGEMENT LLC	New	6.1M	$118M	0.0%	+28.27%	42
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	6.1M	$117.5M	0.0%	+28.27%	42
FMR LLC	Decreased	4.6M(-25.0%)	$87.8M	0.0%	+27.52%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Decreased	4.4M(-11.1%)	$85.1M	0.0%	+19.16%	0
GOLDMAN SACHS GROUP INC	Increased	4.4M(+14.9%)	$84.6M	0.0%	+48.09%	34
BAKER BROS. ADVISORS LP	Unchanged	3.7M	$71.6M	0.4%	+8.89%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	3.7M(+7.8%)	$71.6M	0.0%	-7.88%	32
Holocene Advisors, LP	Increased	3.2M(+1.4%)	$61.4M	0.1%	+76.49%	36
DIMENSIONAL FUND ADVISORS LP	Increased	2.7M(+13.4%)	$51.7M	0.0%	+25.32%	33
UBS Group AG	Increased	2.6M(+6.9%)	$49.4M	0.0%	+50.36%	31
Pictet Asset Management Holding SA	Increased	2.6M(+92.5%)	$48.4M	0.1%	+43.84%	46
Capital Research Global Investors	Decreased	2.5M(-32.6%)	$48.3M	0.0%	+5.67%	0
ALLIANCEBERNSTEIN L.P.	Decreased	2.9M(-18.7%)	$47.8M	0.0%	+5.57%	0
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	2.5M(-37.1%)	$47.3M	0.0%	+27.90%	0
Fisher Asset Management, LLC	Decreased	2.4M(-5.9%)	$46.8M	0.0%	+48.35%	0
AIAlyeska Investment Group, L.P.	Increased	1.9M(+126.0%)	$37.3M	0.1%	+39.40%	56