DESIGN THERAPEUTICS INC

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DSGN·25056L103·US·Common Stock·Healthcare - Biotechnology-Activist

DSGN (DESIGN THERAPEUTICS INC) is held by 81 institutional investors as of Q2 2026. Largest holders: BAKER BROS. ADVISORS LP ($38.8M), DRIEHAUS CAPITAL MANAGEMENT LLC ($38.5M), BlackRock, Inc. ($38.5M). Net institutional sentiment: Mixed.

81

Holders

(6 Elite)

$334.6M

Total Value

65% (83)

Consensus

54 buying - 29 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)54

Insider (Form 4)78

Activist (13D/13G)27

Congressional (STOCK Act)40

Holder Quality

51

★★★★★

Elite

11

★★★★

Strong

59

★★★

Solid

17

★★

Below

76

★

Weak

Held by 81 funds

6 elite

Who's Trading

Source dates: Price Aug 28, 2026 · Insiders Aug 14, 2025 · Activists Aug 14, 2026 · Congress none

ActivistSISirenia Capital Management LP9.5%Aug 14, 2026

ActivistPoint72 Asset Management, L.P.3.8%Aug 14, 2026

ActivistPoint72 Asset Management, L.P.5.1%Jun 9, 2026

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Top Holders

Top Holders (81)History

AllNewIncreasedHeldDecreasedExited

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BAKER BROS. ADVISORS LP	Increased	2.7M(+3.6%)	$38.8M	0.2%	+50.31%	36
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	2.7M(+52.5%)	$38.5M	0.2%	+60.37%	49
BlackRock, Inc.	Increased	2.7M(+24.7%)	$38.5M	0.0%	+96.47%	36
Point72 Asset Management, L.P.	Decreased	2.4M(-13.1%)	$34.2M	0.0%	+116.31%	0
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	1.6M(+16.4%)	$22.7M	0.0%	+46.67%	33
CACaption Management, LLC	Increased	1.1M(+1189.5%)	$16.2M	0.1%	+10.38%	45
GEODE CAPITAL MANAGEMENT, LLC	Increased	958,417(+38.4%)	$13.9M	0.0%	+1.80%	37
FMR LLC	Decreased	776,462(-2.8%)	$11.2M	0.0%	+142.45%	0
MORGAN STANLEY	Increased	765,425(+16.6%)	$11.1M	0.0%	+71.12%	32
STATE STREET CORP	Increased	736,221(+11.6%)	$10.7M	0.0%	+264.67%	31
Woodline Partners LP	Decreased	700,354(-27.2%)	$10.1M	0.0%	+152.72%	0
DIMENSIONAL FUND ADVISORS LP	Increased	694,743(+60.9%)	$10.1M	0.0%	+61.79%	40
GOLDMAN SACHS GROUP INC	Increased	656,584(+30.1%)	$9.5M	0.0%	+63.61%	35
JACOBS LEVY EQUITY MANAGEMENT, INC	Increased	565,597(+95.5%)	$8.2M	0.0%	+28.73%	44
Qube Research & Technologies Ltd	Increased	437,079(+1178.6%)	$6.3M	0.0%	+10.41%	44
RENAISSANCE TECHNOLOGIES LLC	Decreased	387,913(-5.0%)	$5.6M	0.0%	+187.11%	0
NORTHERN TRUST CORP	Increased	353,197(+17.6%)	$5.1M	0.0%	+9.06%	31
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	271,264(+12.3%)	$3.9M	0.0%	+10.38%	30
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	251,442(+81.5%)	$3.6M	0.0%	+29.84%	41
VFVANGUARD FIDUCIARY TRUST CO	Increased	230,202(+17.7%)	$3.3M	0.0%	+46.10%	31

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DSGNDESIGN THERAPEUTICS INC

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer