DESIGN THERAPEUTICS INC (DSGN) is held by 82 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is RA CAPITAL MANAGEMENT, L.P. as of Q1 2026.

Are institutions buying or selling DSGN?

In Q1 2026, 56 institutions opened or increased positions in DESIGN THERAPEUTICS INC while 22 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on DSGN?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for DESIGN THERAPEUTICS INC.

How many hedge funds hold DSGN?

82 institutional investors report holding DESIGN THERAPEUTICS INC (DSGN) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into DSGN?

As of Q1 2026, tracked institutions in DESIGN THERAPEUTICS INC show 56 buyers versus 22 sellers — net inflows.

DESIGN THERAPEUTICS INC

DSGN·25056L103·US·Common Stock·Healthcare - Biotechnology-Activist

Holders

Avg rating(17 Elite)

$241.8M

Total Value

72% (84)

Fund Consensus

56 buying - 22 selling

Smart Money Verdict

View all

Held by 82 funds

17 elite

Who's Trading

Activist

Point72 Asset Management, L.P.5.1%Jun 9, 2026

ActivistSOSR One Capital Fund I Aggregator, LP10.6%Mar 11, 2026

Activist

Point72 Asset Management, L.P.9.4%Feb 17, 2026

ActivistLGLogos Global Management LP4.4%Nov 18, 2025

InsiderWAWilliam ArsaniSell $1.8MAug 13, 2025

InsiderWAWilliam ArsaniSell $1.1MAug 13, 2025

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Increased	3M(+103.4%)	$31.6M	0.3%	+61.14%	56
Point72 Asset Management, L.P.	Decreased	2.7M(-49.3%)	$29M	0.0%	+110.76%	0
BAKER BROS. ADVISORS LP	Increased	2.6M(+15.8%)	$27.5M	0.2%	+48.55%	40
BlackRock, Inc.	Increased	2.1M(+0.8%)	$22.7M	0.0%	+140.22%	29
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	1.7M(+47.9%)	$18.6M	0.1%	+110.14%	46
VAVANGUARD CAPITAL MANAGEMENT LLC	New	1.3M	$14.4M	0.0%	+51.90%	39
Woodline Partners LP	Increased	961,501(+1.9%)	$10.2M	0.0%	+146.24%	28
FMR LLC	Increased	798,411(+3.5%)	$8.5M	0.0%	+136.23%	28
GEODE CAPITAL MANAGEMENT, LLC	Increased	692,518(+1.9%)	$7.4M	0.0%	-2.87%	28
STATE STREET CORP	Increased	659,575(+1.8%)	$7M	0.0%	+391.51%	28
MORGAN STANLEY	Decreased	656,565(-6.5%)	$7M	0.0%	+84.75%	0
GOLDMAN SACHS GROUP INC	Increased	504,718(+86.5%)	$5.4M	0.0%	+88.89%	42
DED. E. Shaw & Co., Inc.	Increased	470,270(+7.2%)	$5M	0.0%	+220.78%	29
DIMENSIONAL FUND ADVISORS LP	Increased	431,840(+45.0%)	$4.6M	0.0%	+126.94%	36
RENAISSANCE TECHNOLOGIES LLC	Increased	408,200(+42.2%)	$4.3M	0.0%	+179.74%	36
NORTHERN TRUST CORP	Increased	300,279(+4.8%)	$3.2M	0.0%	+6.50%	28
JACOBS LEVY EQUITY MANAGEMENT, INC	Increased	289,385(+48.7%)	$3.1M	0.0%	+54.08%	36
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	241,485(+1.9%)	$2.6M	0.0%	+7.87%	27
CITADEL ADVISORS LLC	Decreased	231,513(-49.7%)	$2.5M	0.0%	+25.24%	0
VFVANGUARD FIDUCIARY TRUST CO	New	195,658	$2.1M	0.0%	+51.90%	36