Krystal Biotech, Inc.

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KRYS·501147102·US·Common Stock·Healthcare - Biotechnology-13D/G

KRYS (Krystal Biotech, Inc.) is held by 176 institutional investors as of Q2 2026. Largest holders: FMR LLC ($1.6B), BlackRock, Inc. ($1.6B), Avoro Capital Advisors LLC ($1.1B). Net institutional sentiment: Mixed.

176

Holders

(13 Elite)

$9.3B

Total Value

62% (185)

Consensus

114 buying - 71 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)62

Insider (Form 4)46

Activist (13D/13G)64

Congressional (STOCK Act)82

Holder Quality

56

★★★★★

Elite

70

★★★★

Strong

64

★★★

Solid

22

★★

Below

71

★

Weak

Held by 176 funds

13 elite

Who's Trading

Source dates: Price Aug 21, 2026 · Insiders Jun 26, 2026 · Activists May 4, 2026 · Congress none

InsiderTCThomas John CharlesSell $347KJun 25, 2026

ActivistKSKrish S. Krishnan11.5%May 4, 2026

ActivistVPVanguard Portfolio Management5.0%Apr 29, 2026

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Top Holders

Top Holders (176)History

AllNewIncreasedHeldDecreasedExited

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	4.4M(+1.0%)	$1.6B	0.1%	+113.08%	32
BlackRock, Inc.	Increased	4.2M(+6.1%)	$1.6B	0.0%	+98.89%	34
Avoro Capital Advisors LLC	Unchanged	2.9M	$1.1B	9.6%	+230.25%	0
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	1.6M(+8.1%)	$585.3M	0.0%	+27.47%	34
STATE STREET CORP	Increased	1.4M(+2.8%)	$502.2M	0.0%	+129.57%	32
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	1.2M(+6.5%)	$461.1M	0.0%	+28.20%	33
Capital World Investors	Decreased	777,843(-5.7%)	$289.1M	0.0%	+87.76%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	698,993(+8.5%)	$259.8M	0.0%	+195.72%	33
Hood River Capital Management LLC	Increased	663,375(+7.1%)	$246.6M	1.8%	+212.69%	52
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	Increased	570,153(+40.0%)	$211.9M	0.6%	+33.58%	57
DIMENSIONAL FUND ADVISORS LP	Increased	476,038(+1.5%)	$176.9M	0.0%	+240.56%	31
FIRST TRUST ADVISORS LP	Decreased	324,900(-7.3%)	$120.8M	0.1%	+89.47%	0
Invesco Ltd.	Increased	324,755(+29.2%)	$120.7M	0.0%	+28.17%	38
GOLDMAN SACHS GROUP INC	Increased	298,841(+39.0%)	$111.1M	0.0%	+64.37%	40
NORTHERN TRUST CORP	Increased	283,784(+12.4%)	$105.5M	0.0%	+215.12%	34
FRANKLIN RESOURCES INC	Increased	261,917(+46.1%)	$97.3M	0.0%	+21.85%	41
BANK OF AMERICA CORP /DE/	Decreased	256,431(-1.6%)	$95.3M	0.0%	+68.43%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	254,828(+5.3%)	$94.7M	0.0%	+228.09%	32
MORGAN STANLEY	Increased	235,491(+12.6%)	$87.5M	0.0%	+69.26%	34
VFVANGUARD FIDUCIARY TRUST CO	Increased	189,528(+5.8%)	$70.4M	0.0%	+28.51%	31

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KRYSKrystal Biotech, Inc.

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer