LEXEO THERAPEUTICS INC (LXEO) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling LXEO?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for LEXEO THERAPEUTICS INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on LXEO?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for LEXEO THERAPEUTICS INC.

Is institutional money flowing into LXEO?

83 institutional investors hold LEXEO THERAPEUTICS INC (LXEO). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about LXEO?

Track institutional sentiment and conviction scores for LEXEO THERAPEUTICS INC (LXEO) including Smart Money Verdict and position changes on HoldingsIntel.

LEXEO THERAPEUTICS INC

LXEO·52886X107·US·equity·Healthcare - Biotechnology-13D/G

LXEO (LEXEO THERAPEUTICS INC) is held by 83 institutional investors as of Q4 2025. Largest holders: JANUS HENDERSON GROUP PLC ($54.7M), RA CAPITAL MANAGEMENT, L.P. ($49.7M), BlackRock, Inc. ($48.7M). Net institutional sentiment: Bullish.

Holders

Avg rating(6 Elite)

$469.6M

Total Value

75% (89)

Fund Consensus

60 buying - 20 selling

Smart Money Verdict- Q4 2025View all

53Mixed MomentumSplit Signals

Held by 83 funds

6 elite

Who's Trading

InsiderTownsend Richard NolanSell $313KApr 6, 2026

Activist

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
JANUS HENDERSON GROUP PLC	Decreased	5.5M(-9.8%)	$54.7M	0.0%	-28.46%	0
RA CAPITAL MANAGEMENT, L.P.	New	5M	$49.7M	0.5%	-27.41%	57
BlackRock, Inc.	Increased	4.9M(+126.0%)	$48.7M	0.0%	-15.05%	47
VANGUARD GROUP INC	Increased	3.9M(+74.9%)	$38.7M	0.0%	-10.70%	44
CITADEL ADVISORS LLC	Increased	3.8M(+1.5%)	$37.5M	0.0%	-36.24%	29
Avoro Capital Advisors LLC	New	3.3M	$32.8M	0.3%	-27.41%	49
Woodline Partners LP	Increased	3.2M(+24.3%)	$31.8M	0.1%	-14.40%	42
STATE STREET CORP	Increased	3.2M(+485.1%)	$31.7M	0.0%	-27.64%	47
Point72 Asset Management, L.P.	Decreased	1.9M(-2.4%)	$18.8M	0.0%	+6.30%	0
BALYASNY ASSET MANAGEMENT L.P.	Decreased	1.6M(-58.2%)	$16.2M	0.0%	+71.60%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.4M(+100.3%)	$14.4M	0.0%	-31.29%	45
MILLENNIUM MANAGEMENT LLC	Decreased	908,024(-60.8%)	$9M	0.0%	+62.45%	0
Blackstone Inc.	Decreased	904,959(-19.6%)	$9M	0.0%	-42.78%	0
DIMENSIONAL FUND ADVISORS LP	Decreased	862,892(-5.4%)	$8.6M	0.0%	+8.28%	0
GOLDMAN SACHS GROUP INC	Increased	781,855(+449.1%)	$7.8M	0.0%	-22.93%	44
D. E. Shaw & Co., Inc.	Increased	480,205(+3646.3%)	$4.8M	0.0%	-26.79%	43
Invesco Ltd.	New	463,029	$4.6M	0.0%	-27.41%	37
NORTHERN TRUST CORP	Increased	457,052(+93.3%)	$4.5M	0.0%	-31.78%	43
Verition Fund Management LLC	Increased	428,458(+3.3%)	$4.3M	0.0%	-43.75%	28
TWO SIGMA INVESTMENTS, LP	Increased	400,567(+372.6%)	$4M	0.0%	-18.24%	43
AQR CAPITAL MANAGEMENT LLC	Decreased	337,386(-3.0%)	$3.4M	0.0%	+32.02%	0
UBS Group AG	Increased	281,083(+12.5%)	$2.8M	0.0%	+38.68%	30
BNP PARIBAS FINANCIAL MARKETS	Increased	257,417(+737.8%)	$2.6M	0.0%	-24.32%	42
AMERIPRISE FINANCIAL INC	Increased	243,294(+46.1%)	$2.4M	0.0%	-7.36%	36
RENAISSANCE TECHNOLOGIES LLC	Increased	217,772(+45.9%)	$2.2M	0.0%	+10.68%	35
Nuveen, LLC	Increased	211,529(+539.0%)	$2.1M	0.0%	-20.18%	42
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	192,210(+81.7%)	$1.9M	0.0%	-26.27%	40
BARCLAYS PLC	Increased	188,754(+69.2%)	$1.9M	0.0%	-11.23%	38
Bank of New York Mellon Corp	Increased	166,749(+132.6%)	$1.7M	0.0%	-29.07%	41
BANK OF AMERICA CORP /DE/	Increased	160,288(+466.8%)	$1.6M	0.0%	-22.33%	41
MORGAN STANLEY	Increased	140,181(+43.0%)	$1.4M	0.0%	-20.61%	34
JANE STREET GROUP, LLC	Increased	140,096(+8.2%)	$1.4M	0.0%	+2.56%	28
Qube Research & Technologies Ltd	New	133,257	$1.3M	0.0%	-27.41%	35
Rafferty Asset Management, LLC	New	102,159	$1M	0.0%	-27.41%	35
Squarepoint Ops LLC	New	92,608	$919,597	0.0%	-27.41%	35
WELLINGTON MANAGEMENT GROUP LLP	New	83,230	$826,474	0.0%	-27.41%	34
TWO SIGMA ADVISERS, LP	New	81,300	$807,309	0.0%	-27.41%	34
WELLS FARGO & COMPANY/MN	Increased	70,736(+267.2%)	$702,408	0.0%	-24.07%	40
RHUMBLINE ADVISERS	Increased	69,369(+118.4%)	$688,827	0.0%	-29.92%	40
ALLIANCEBERNSTEIN L.P.	Increased	61,810(+110.5%)	$613,773	0.0%	-26.08%	39
DEUTSCHE BANK AG\	Increased	57,166(+135.0%)	$567,659	0.0%	-16.93%	39
AMERICAN CENTURY COMPANIES INC	Increased	45,988(+27.2%)	$456,661	0.0%	-3.40%	30
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	37,009(+27.9%)	$367,499	0.0%	+22.85%	20
MetLife Investment Management, LLC	New	35,721	$354,710	0.0%	-27.41%	33
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	35,257(+207.8%)	$348,970	0.0%	-30.73%	38
PANAGORA ASSET MANAGEMENT INC	Unchanged	34,297	$340,569	0.0%	+72.44%	0
JPMORGAN CHASE & CO	Increased	29,861(+108.0%)	$296,520	0.0%	-13.47%	26
Mitsubishi UFJ Asset Management Co., Ltd.	New	26,209	$251,868	0.0%	-27.41%	32
IEQ CAPITAL, LLC	Decreased	24,692(-26.5%)	$245,192	0.0%	+22.67%	0
Cerity Partners LLC	Decreased	22,439(-4.9%)	$222,819	0.0%	+32.90%	0
OMERS ADMINISTRATION Corp	New	20,900	$207,537	0.0%	-27.41%	32
NEW YORK STATE COMMON RETIREMENT FUND	Increased	19,887(+375.0%)	$197,478	0.0%	-35.68%	37
MANUFACTURERS LIFE INSURANCE COMPANY, THE	New	19,147	$190,130	0.0%	-27.41%	31
Vanguard Personalized Indexing Management, LLC	Decreased	16,436(-1.0%)	$163,209	0.0%	+62.00%	0
Police & Firemen's Retirement System of New Jersey	Increased	16,373(+171.1%)	$162,584	0.0%	-17.40%	36
CITIGROUP INC	Increased	15,293(+105.8%)	$151,859	0.0%	-13.62%	36
ProShare Advisors LLC	New	14,752	$146,487	0.0%	-27.41%	31
INTECH INVESTMENT MANAGEMENT LLC	Increased	14,188(+19.5%)	$140,887	0.0%	+5.27%	26
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	Increased	14,330(+0.6%)	$136,278	0.0%	+5.86%	22
FMR LLC	Decreased	13,388(-0.3%)	$132,943	0.0%	+47.70%	0
SIMPLEX TRADING, LLC	Increased	13,031(+2511.4%)	$129,397	0.0%	-26.52%	36
RAYMOND JAMES FINANCIAL INC	New	12,538	$124,503	0.0%	-27.41%	34
COMMONWEALTH EQUITY SERVICES, LLC	Increased	11,234(+3.2%)	$111,550	0.0%	+58.86%	23
XTX Topco Ltd	Decreased	11,144(-58.3%)	$110,660	0.0%	+6.16%	0
VOYA INVESTMENT MANAGEMENT LLC	New	10,976	$108,992	0.0%	-27.41%	30
LOS ANGELES CAPITAL MANAGEMENT LLC	Increased	11,555(+4.3%)	$108,963	0.0%	+4.16%	23
Creative Planning	New	10,358	$102,855	0.0%	-27.41%	30
ROYAL BANK OF CANADA	Decreased	6,721(-1.9%)	$67,000	0.0%	+21.17%	0
Russell Investments Group, Ltd.	Increased	5,872(+160.2%)	$58,308	0.0%	-16.44%	34
Legal & General Group Plc	Increased	5,631(+177.1%)	$55,916	0.0%	-30.61%	23
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	3,884(+123.7%)	$38,568	0.0%	-34.00%	22
Mirae Asset Global Investments Co., Ltd.	Increased	3,547(+69.9%)	$35,222	0.0%	-7.90%	29
Allworth Financial LP	Increased	3,386(+1002.9%)	$33,623	0.0%	-25.27%	32
NISA INVESTMENT ADVISORS, LLC	Unchanged	2,765	$27,456	0.0%	+60.07%	0
GROUP ONE TRADING LLC	New	1,816	$18,033	0.0%	-27.41%	28
Rockefeller Capital Management L.P.	Increased	700(+250.0%)	$6,951	0.0%	-20.20%	18
US BANCORP \DE\	New	555	$5,511	0.0%	-27.41%	23
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	487(-27.6%)	$4,836	0.0%	+6.16%	0
Optiver Holding B.V.	Unchanged	312	$3,098	0.0%	+6.16%	0
Steward Partners Investment Advisory, LLC	Unchanged	100	$993	0.0%	-22.39%	0
Farther Finance Advisors, LLC	New	57	$566	0.0%	-27.41%	17
OSAIC HOLDINGS, INC.	Decreased	57(-66.5%)	$566	0.0%	+38.87%	0
PRICE T ROWE ASSOCIATES INC /MD/	Increased	33,872(+183.1%)	$337	0.0%	-17.93%	12
ExodusPoint Capital Management, LP	Exited	0(-100.0%)	$181,803	0.0%	+46.25%	0
Savant Capital, LLC	Exited	0(-100.0%)	$231,829	0.0%	+116.36%	0
HRT FINANCIAL LP	Exited	0(-100.0%)	$142	0.0%	+46.25%	0
D1 Capital Partners L.P.	Exited	0(-100.0%)	$6.5M	0.0%	-27.42%	0
Brevan Howard Capital Management LP	Exited	0(-100.0%)	$122,176	0.0%	+46.25%	0
Virtu Financial LLC	Exited	0(-100.0%)	$287	0.0%	+46.25%	0

LEXEO THERAPEUTICS INC

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