Maze Therapeutics, Inc. (MAZE) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling MAZE?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Maze Therapeutics, Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on MAZE?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Maze Therapeutics, Inc..

Is institutional money flowing into MAZE?

76 institutional investors hold Maze Therapeutics, Inc. (MAZE). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about MAZE?

Track institutional sentiment and conviction scores for Maze Therapeutics, Inc. (MAZE) including Smart Money Verdict and position changes on HoldingsIntel.

Maze Therapeutics, Inc.

MAZE·578784100·US·equity·Healthcare - Biotechnology-13D/G

MAZE (Maze Therapeutics, Inc.) is held by 76 institutional investors as of Q4 2025. Largest holders: JANUS HENDERSON GROUP PLC ($130.2M), BlackRock, Inc. ($94.8M), VANGUARD GROUP INC ($70.3M). Net institutional sentiment: Bullish.

Holders

Avg rating(5 Elite)

$620M

Total Value

81% (79)

Fund Consensus

60 buying - 14 selling

Smart Money VerdictView all

45Weak MomentumSplit Signals

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See how MAZE's score breaks down across 4 SEC sources

Held by 76 funds

5 elite

Who's Trading

InsiderBachrodt AmySell $65KApr 1, 2026

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
JANUS HENDERSON GROUP PLC	Increased	3.1M(+318.0%)	$130.2M	0.1%	—	49
BlackRock, Inc.	Increased	2.3M(+73.8%)	$94.8M	0.0%	—	45
VANGUARD GROUP INC	Increased	1.7M(+27.1%)	$70.3M	0.0%	—	37
Woodline Partners LP	Unchanged	1M	$42.9M	0.2%	—	0
MARSHALL WACE, LLP	Increased	847,472(+9.0%)	$35.1M	0.0%	—	32
FMR LLC	Increased	728,605(+11.1%)	$30.2M	0.0%	—	32
STATE STREET CORP	Increased	533,005(+38.5%)	$22.1M	0.0%	—	38
GEODE CAPITAL MANAGEMENT, LLC	Increased	527,281(+11.3%)	$21.9M	0.0%	—	32
HHLR ADVISORS, LTD.	Unchanged	457,535	$19M	0.6%	—	0
CITADEL ADVISORS LLC	New	448,217	$18.6M	0.0%	—	39
DRIEHAUS CAPITAL MANAGEMENT LLC	Unchanged	378,015	$15.7M	0.1%	—	0
MORGAN STANLEY	Increased	258,086(+21.3%)	$10.7M	0.0%	—	33
BALYASNY ASSET MANAGEMENT L.P.	Decreased	199,212(-54.1%)	$8.3M	0.0%	—	0
Alyeska Investment Group, L.P.	Increased	196,124(+56.9%)	$8.1M	0.0%	—	39
Ensign Peak Advisors, Inc	Increased	185,794(+162.9%)	$7.7M	0.0%	—	44
NORTHERN TRUST CORP	Decreased	176,259(-0.4%)	$7.3M	0.0%	—	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	175,969(+4.8%)	$7.3M	0.0%	—	29
MILLENNIUM MANAGEMENT LLC	New	154,470	$6.4M	0.0%	—	38
Invesco Ltd.	Increased	134,033(+1.5%)	$5.6M	0.0%	—	27
Freestone Grove Partners LP	New	118,876	$4.9M	0.0%	—	37
GOLDMAN SACHS GROUP INC	New	114,455	$4.7M	0.0%	—	37
AMERIPRISE FINANCIAL INC	New	96,688	$4M	0.0%	—	37
RAYMOND JAMES FINANCIAL INC	New	67,718	$2.8M	0.0%	—	36
WELLINGTON MANAGEMENT GROUP LLP	New	61,205	$2.5M	0.0%	—	36
Bank of New York Mellon Corp	Increased	60,436(+33.6%)	$2.5M	0.0%	—	34
OSAIC HOLDINGS, INC.	Increased	59,762(+95.8%)	$2.5M	0.0%	—	42
Nuveen, LLC	Increased	57,258(+89.0%)	$2.4M	0.0%	—	41
FRANKLIN RESOURCES INC	Increased	55,229(+203.5%)	$2.3M	0.0%	—	42
Trexquant Investment LP	New	52,459	$2.2M	0.0%	—	36
Schonfeld Strategic Advisors LLC	Decreased	48,200(-57.7%)	$2M	0.0%	—	0
BARCLAYS PLC	Increased	39,508(+43.6%)	$1.6M	0.0%	—	35
D. E. Shaw & Co., Inc.	New	33,694	$1.4M	0.0%	—	35
ALLIANCEBERNSTEIN L.P.	Decreased	33,220(-44.7%)	$1.4M	0.0%	—	0
XTX Topco Ltd	Increased	33,021(+22.9%)	$1.4M	0.0%	—	31
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	31,295(+244.7%)	$1.3M	0.0%	—	41
UBS Group AG	Increased	28,698(+3.3%)	$1.2M	0.0%	—	26
AQR CAPITAL MANAGEMENT LLC	Decreased	27,439(-0.6%)	$1.1M	0.0%	—	0
RENAISSANCE TECHNOLOGIES LLC	Decreased	27,100(-68.5%)	$1.1M	0.0%	—	0
TUDOR INVESTMENT CORP ET AL	New	24,059	$996,764	0.0%	—	35
WELLS FARGO & COMPANY/MN	Increased	24,008(+62.5%)	$994,651	0.0%	—	36
RHUMBLINE ADVISERS	Increased	23,731(+13.2%)	$983,165	0.0%	—	28
GILDER GAGNON HOWE & CO LLC	New	23,282	$964,573	0.0%	—	35
Russell Investments Group, Ltd.	Increased	22,545(+1082.2%)	$934,038	0.0%	—	40
Verition Fund Management LLC	New	22,512	$932,672	0.0%	—	35
AMERICAN CENTURY COMPANIES INC	New	21,509	$891,118	0.0%	—	34
JPMORGAN CHASE & CO	Increased	20,007(+153.6%)	$828,890	0.0%	—	40
BANK OF AMERICA CORP /DE/	Increased	18,381(+92.0%)	$761,524	0.0%	—	39
DEUTSCHE BANK AG\	Increased	15,522(+74.7%)	$643,076	0.0%	—	37
LOS ANGELES CAPITAL MANAGEMENT LLC	New	19,100	$634,502	0.0%	—	34
TWO SIGMA ADVISERS, LP	New	14,800	$613,164	0.0%	—	34
MetLife Investment Management, LLC	Unchanged	11,801	$488,915	0.0%	—	0
CITIGROUP INC	Increased	11,252(+4082.9%)	$466,171	0.0%	—	39
STRS OHIO	Decreased	11,200(-37.4%)	$464,016	0.0%	—	0
TWO SIGMA INVESTMENTS, LP	Decreased	7,245(-35.0%)	$300,160	0.0%	—	0
MANUFACTURERS LIFE INSURANCE COMPANY, THE	New	6,897	$285,743	0.0%	—	32
NEW YORK STATE COMMON RETIREMENT FUND	Unchanged	6,700	$277,581	0.0%	—	0
INTECH INVESTMENT MANAGEMENT LLC	New	6,443	$266,933	0.0%	—	32
ProShare Advisors LLC	New	6,047	$250,528	0.0%	—	32
Police & Firemen's Retirement System of New Jersey	Increased	5,961(+18.5%)	$246,964	0.0%	—	27
SEI INVESTMENTS CO	New	5,668	$234,825	0.0%	—	32
BNP PARIBAS FINANCIAL MARKETS	Decreased	5,473(-54.5%)	$226,746	0.0%	—	0
CIBC Private Wealth Group LLC	New	5,400	$223,722	0.0%	—	32
Legal & General Group Plc	Increased	5,379(+3.1%)	$222,852	0.0%	—	16
Rafferty Asset Management, LLC	New	5,244	$217,259	0.0%	—	32
Brevan Howard Capital Management LP	New	5,042	$208,890	0.0%	—	32
Mirae Asset Global Investments Co., Ltd.	New	2,338	$96,863	0.0%	—	30
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	1,321(+138.0%)	$54,729	0.0%	—	33
ROYAL BANK OF CANADA	Increased	646(+128.3%)	$27,000	0.0%	—	21
Farther Finance Advisors, LLC	Decreased	359(-6.3%)	$14,873	0.0%	—	0
NISA INVESTMENT ADVISORS, LLC	Increased	204(+684.6%)	$8,452	0.0%	—	18
PRICE T ROWE ASSOCIATES INC /MD/	Increased	115,711(+1004.8%)	$4,794	0.0%	—	24
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	New	99	$4,102	0.0%	—	22
JONES FINANCIAL COMPANIES LLLP	New	90	$3,729	0.0%	—	21
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	58(-37.6%)	$2,403	0.0%	—	0
US BANCORP \DE\	New	41	$1,699	0.0%	—	17
Allworth Financial LP	New	5	$208	0.0%	—	17
Caption Management, LLC	Exited	0(-100.0%)	$103,720	0.0%	—	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Exited	0(-100.0%)	$419,158	0.0%	—	0
ALPS ADVISORS INC	Exited	0(-100.0%)	$356,330	0.0%	—	0

Maze Therapeutics, Inc.

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