Mineralys Therapeutics, Inc. (MLYS) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling MLYS?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Mineralys Therapeutics, Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on MLYS?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Mineralys Therapeutics, Inc..

Is institutional money flowing into MLYS?

113 institutional investors hold Mineralys Therapeutics, Inc. (MLYS). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about MLYS?

Track institutional sentiment and conviction scores for Mineralys Therapeutics, Inc. (MLYS) including Smart Money Verdict and position changes on HoldingsIntel.

Mineralys Therapeutics, Inc.

MLYS·603170101·US·equity·Healthcare - Biotechnology-Activist

MLYS (Mineralys Therapeutics, Inc.) is held by 113 institutional investors as of Q4 2025. Largest holders: RA CAPITAL MANAGEMENT, L.P. ($265.8M), FMR LLC ($183.5M), BlackRock, Inc. ($157.1M). Net institutional sentiment: Mixed.

113

Holders

Avg rating(6 Elite)

$1.8B

Total Value

63% (122)

Fund Consensus

73 buying - 43 selling

Smart Money VerdictView all

59Mixed MomentumStrong Convergence

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See how MLYS's score breaks down across 4 SEC sources

Held by 113 funds

6 elite

Who's Trading

InsiderRodman David MalcomSell $373KApr 13, 2026

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	7.3M	$265.8M	2.7%	+52.82%	0
FMR LLC	Increased	5.1M(+144.2%)	$183.5M	0.0%	-19.60%	49
BlackRock, Inc.	Increased	4.3M(+17.9%)	$157.1M	0.0%	+43.31%	36
VANGUARD GROUP INC	Increased	3.4M(+11.1%)	$121.7M	0.0%	+38.49%	33
STATE STREET CORP	Increased	3.2M(+144.4%)	$115.6M	0.0%	+9.37%	49
FRANKLIN RESOURCES INC	Decreased	1.8M(-1.2%)	$64.9M	0.0%	+126.27%	0
Holocene Advisors, LP	Increased	1.6M(+32.9%)	$58.1M	0.1%	-25.75%	45
GOLDMAN SACHS GROUP INC	Increased	1.5M(+103.9%)	$52.7M	0.0%	+8.23%	47
Polar Capital Holdings Plc	Increased	1.4M(+32.3%)	$50.8M	0.2%	-25.77%	45
JENNISON ASSOCIATES LLC	Increased	1.3M(+234.4%)	$45.7M	0.0%	-1.12%	47
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.3M(+11.9%)	$45.6M	0.0%	+47.52%	33
JANUS HENDERSON GROUP PLC	Increased	1.2M(+6012.8%)	$44M	0.0%	-19.28%	47
Point72 Asset Management, L.P.	Decreased	1.2M(-32.9%)	$43.8M	0.0%	-27.55%	0
Capital International Investors	Decreased	1.2M(-51.4%)	$42.2M	0.0%	+107.95%	0
D. E. Shaw & Co., Inc.	Increased	1.2M(+88.3%)	$41.8M	0.0%	+13.39%	46
BANK OF AMERICA CORP /DE/	Increased	987,280(+28.5%)	$35.8M	0.0%	-9.68%	36
ALLIANCEBERNSTEIN L.P.	Increased	922,516(+4.5%)	$33.5M	0.0%	-25.81%	30
AMERICAN CENTURY COMPANIES INC	Increased	908,093(+3.2%)	$33M	0.0%	+93.26%	30
Pictet Asset Management Holding SA	Decreased	852,883(-8.2%)	$31M	0.0%	+95.01%	0
FARALLON CAPITAL MANAGEMENT LLC	Decreased	823,296(-50.8%)	$29.9M	0.1%	-27.55%	0
WELLINGTON MANAGEMENT GROUP LLP	Increased	784,267(+0.1%)	$28.5M	0.0%	-19.52%	29
Candriam S.C.A.	Increased	678,387(+19.5%)	$24.6M	0.1%	+63.49%	40
MORGAN STANLEY	Decreased	639,507(-53.6%)	$23.2M	0.0%	+3.09%	0
TWO SIGMA INVESTMENTS, LP	New	610,403	$22.2M	0.0%	-19.69%	39
Qube Research & Technologies Ltd	Increased	496,549(+175.2%)	$18M	0.0%	+3.36%	46
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	461,300(+12.7%)	$16.7M	0.0%	+37.31%	32
CITADEL ADVISORS LLC	Decreased	399,919(-80.7%)	$14.5M	0.0%	-27.23%	0
TWO SIGMA ADVISERS, LP	New	353,700	$12.8M	0.0%	-19.69%	39
RENAISSANCE TECHNOLOGIES LLC	Increased	322,100(+579.5%)	$11.7M	0.0%	-11.23%	45
NORTHERN TRUST CORP	Decreased	299,863(-23.3%)	$10.9M	0.0%	+70.02%	0
MARSHALL WACE, LLP	New	249,130	$9M	0.0%	-19.69%	38
Squarepoint Ops LLC	Increased	246,804(+473.8%)	$9M	0.0%	-18.48%	44
BARCLAYS PLC	Decreased	223,283(-65.8%)	$8.1M	0.0%	-15.13%	0
Swedbank AB	Decreased	221,400(-26.0%)	$8M	0.0%	+96.33%	0
UBS Group AG	Increased	201,280(+124.9%)	$7.3M	0.0%	+11.40%	44
Russell Investments Group, Ltd.	Increased	175,361(+5272.6%)	$6.4M	0.0%	-19.84%	44
BNP PARIBAS FINANCIAL MARKETS	Decreased	172,929(-72.4%)	$6.3M	0.0%	-27.25%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	143,208(+150.3%)	$5.2M	0.0%	+4.81%	44
DIMENSIONAL FUND ADVISORS LP	Decreased	137,636(-6.2%)	$5M	0.0%	+104.63%	0
Brevan Howard Capital Management LP	New	139,293	$5M	0.1%	-19.69%	37
Bank of New York Mellon Corp	Increased	131,839(+15.8%)	$4.8M	0.0%	+42.95%	31
Rafferty Asset Management, LLC	Increased	127,917(+303.7%)	$4.6M	0.0%	-5.29%	43
SCHRODER INVESTMENT MANAGEMENT GROUP	New	130,592	$4.6M	0.0%	-19.69%	37
Nuveen, LLC	Increased	122,947(+41.5%)	$4.5M	0.0%	+26.41%	36
Trexquant Investment LP	Increased	112,788(+156.5%)	$4.1M	0.0%	+4.58%	43
VOYA INVESTMENT MANAGEMENT LLC	Decreased	112,672(-18.7%)	$4.1M	0.0%	-5.34%	0
Ensign Peak Advisors, Inc	Increased	112,190(+4.2%)	$4.1M	0.0%	+91.20%	28
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	New	111,753	$4.1M	0.0%	-19.69%	37
Swiss National Bank	Increased	90,100(+1.8%)	$3.3M	0.0%	+31.59%	27
PRUDENTIAL FINANCIAL INC	Increased	89,065(+76.6%)	$3.2M	0.0%	+24.84%	40
Verition Fund Management LLC	Increased	83,840(+354.1%)	$3M	0.0%	-21.56%	43
MILLENNIUM MANAGEMENT LLC	Decreased	78,625(-80.6%)	$2.9M	0.0%	+23.36%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	75,897(+28.6%)	$2.8M	0.0%	-6.06%	33
XTX Topco Ltd	Increased	73,678(+291.1%)	$2.7M	0.1%	-21.86%	42
ALPS ADVISORS INC	New	64,987	$2.4M	0.0%	-19.69%	36
AQR CAPITAL MANAGEMENT LLC	Increased	62,300(+243.8%)	$2.3M	0.0%	-3.15%	42
MOORE CAPITAL MANAGEMENT, LP	Decreased	60,000(-63.6%)	$2.2M	0.0%	-27.55%	0
WELLS FARGO & COMPANY/MN	Increased	56,756(+88.8%)	$2.1M	0.0%	+23.64%	41
RHUMBLINE ADVISERS	Decreased	54,284(-1.8%)	$2M	0.0%	+104.77%	0
STATE OF WISCONSIN INVESTMENT BOARD	Increased	49,941(+85.5%)	$1.8M	0.0%	+13.29%	40
Schonfeld Strategic Advisors LLC	Increased	49,821(+240.8%)	$1.8M	0.0%	-2.85%	42
JPMORGAN CHASE & CO	Decreased	46,683(-74.6%)	$1.7M	0.0%	-20.04%	0
AMERIPRISE FINANCIAL INC	Decreased	46,246(-52.4%)	$1.7M	0.0%	+9.96%	0
Erste Asset Management GmbH	Unchanged	45,000	$1.7M	0.0%	+94.47%	0
Legal & General Group Plc	Decreased	43,938(-3.3%)	$1.6M	0.0%	+50.35%	0
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	43,348(+18.4%)	$1.6M	0.0%	+65.97%	30
TUDOR INVESTMENT CORP ET AL	New	39,046	$1.4M	0.0%	-19.69%	35
DEUTSCHE BANK AG\	Increased	37,245(+20.4%)	$1.4M	0.0%	+60.10%	30
VICTORY CAPITAL MANAGEMENT INC	Increased	32,881(+476.1%)	$1.2M	0.0%	-21.17%	41
Allianz Asset Management GmbH	Decreased	30,200(-10.4%)	$1.1M	0.0%	-4.94%	0
CANADA PENSION PLAN INVESTMENT BOARD	New	29,600	$1.1M	0.0%	-19.69%	35
Invesco Ltd.	Decreased	29,141(-84.5%)	$1.1M	0.0%	-20.74%	0
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	29,182(+48.0%)	$1.1M	0.0%	+43.07%	34
MetLife Investment Management, LLC	Increased	26,005(+14.5%)	$943,721	0.0%	+78.30%	29
RAYMOND JAMES FINANCIAL INC	New	24,974	$906,306	0.0%	-19.69%	34
Creative Planning	Decreased	21,103(-5.3%)	$765,828	0.0%	+107.95%	0
CITIGROUP INC	Decreased	18,315(-88.8%)	$664,651	0.0%	-18.39%	0
Quantinno Capital Management LP	Decreased	18,243(-2.1%)	$662,038	0.0%	+33.95%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Decreased	17,348(-22.3%)	$629,559	0.0%	+107.95%	0
INTECH INVESTMENT MANAGEMENT LLC	New	16,723	$606,878	0.0%	-19.69%	34
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Increased	16,181(+9.6%)	$587,208	0.0%	+100.74%	27
State of New Jersey Common Pension Fund D	New	15,584	$565,543	0.0%	-19.69%	34
Arizona State Retirement System	Increased	13,000(+22.6%)	$471,770	0.0%	-26.22%	29
Police & Firemen's Retirement System of New Jersey	Increased	12,683(+15.7%)	$460,266	0.0%	+46.27%	28
NEW YORK STATE COMMON RETIREMENT FUND	Unchanged	12,564	$455,948	0.0%	+20.29%	0
ProShare Advisors LLC	Increased	12,040(+33.0%)	$436,932	0.0%	+49.17%	31
Universal- Beteiligungs- und Servicegesellschaft mbH	New	11,997	$435,371	0.0%	-19.69%	33
Mariner, LLC	Decreased	10,230(-37.7%)	$371,452	0.0%	+107.95%	0
KLP KAPITALFORVALTNING AS	Increased	9,600(+43.3%)	$348,384	0.0%	+40.50%	32
VIRGINIA RETIREMENT SYSTEMS ET Al	New	9,350	$339,312	0.0%	-19.69%	33
SEI INVESTMENTS CO	Decreased	8,780(-11.0%)	$318,624	0.0%	-27.55%	0
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	7,561	$274,389	0.0%	-27.55%	0
BANQUE PICTET & CIE SA	New	7,486	$271,667	0.0%	-19.69%	32
Connor, Clark & Lunn Investment Management Ltd.	Decreased	6,860(-51.9%)	$248,949	0.0%	-27.55%	0
TEACHER RETIREMENT SYSTEM OF TEXAS	Decreased	6,781(-30.0%)	$246,082	0.0%	-27.55%	0
NEOS Investment Management LLC	New	6,463	$234,542	0.0%	-19.69%	32
SIMPLEX TRADING, LLC	Increased	4,802(+8.6%)	$174,264	0.0%	-26.98%	25
Mirae Asset Global Investments Co., Ltd.	Increased	3,846(+50.1%)	$139,571	0.0%	+39.55%	31
PNC FINANCIAL SERVICES GROUP, INC.	Unchanged	2,234	$81,072	0.0%	+226.72%	0
NISA INVESTMENT ADVISORS, LLC	Decreased	1,949(-5.6%)	$70,729	0.0%	+98.80%	0
ROYAL BANK OF CANADA	Increased	1,529(+262.3%)	$56,000	0.0%	-3.16%	23
PRICE T ROWE ASSOCIATES INC /MD/	Increased	1.3M(+6097.1%)	$48,089	0.0%	-18.94%	33
OSAIC HOLDINGS, INC.	Decreased	1,155(-96.0%)	$41,915	0.0%	-25.29%	0
COMERICA BANK	Increased	781(+0.1%)	$28,319	0.0%	+172.93%	19
LOS ANGELES CAPITAL MANAGEMENT LLC	New	275	$11,308	0.0%	-19.69%	27
Allworth Financial LP	Increased	219(+397.7%)	$7,948	0.0%	-11.73%	18
Rockefeller Capital Management L.P.	Increased	134(+332.3%)	$4,863	0.0%	-21.66%	16
US BANCORP \DE\	Decreased	81(-60.3%)	$2,939	0.0%	+59.97%	0
Optiver Holding B.V.	Decreased	42(-85.3%)	$1,524	0.0%	-27.55%	0
HRT FINANCIAL LP	Decreased	37,236(-72.2%)	$1,351	0.0%	-23.82%	0
Farther Finance Advisors, LLC	Increased	35(+6.1%)	$1,270	0.0%	+17.84%	8
MAI Capital Management	Increased	24(+33.3%)	$871	0.0%	+48.82%	10
NOMURA ASSET MANAGEMENT CO LTD	Unchanged	0	$0	0.0%	+94.47%	0
BALYASNY ASSET MANAGEMENT L.P.	Exited	0(-100.0%)	$578,963	0.0%	+149.75%	0
ADAGE CAPITAL PARTNERS GP, L.L.C.	Exited	0(-100.0%)	$4M	0.0%	-9.78%	0
Hudson Bay Capital Management LP	Exited	0(-100.0%)	$2.9M	0.0%	-9.78%	0
Caption Management, LLC	Exited	0(-100.0%)	$492,960	0.0%	+158.94%	0
Jain Global LLC	Exited	0(-100.0%)	$4.6M	0.0%	-9.78%	0
CAPSTONE INVESTMENT ADVISORS, LLC	Exited	0(-100.0%)	$1.6M	0.0%	-9.78%	0
JANE STREET GROUP, LLC	Exited	0(-100.0%)	$1.4M	0.0%	-9.78%	0
FEDERATED HERMES, INC.	Exited	0(-100.0%)	$796	0.0%	+164.66%	0
ExodusPoint Capital Management, LP	Exited	0(-100.0%)	$252,926	0.0%	+158.94%	0

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