OPKO HEALTH INC (OPK) is held by 119 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is BlackRock, Inc. as of Q1 2026.

Are institutions buying or selling OPK?

In Q1 2026, 60 institutions opened or increased positions in OPKO HEALTH INC while 51 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on OPK?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for OPKO HEALTH INC.

How many hedge funds hold OPK?

119 institutional investors report holding OPKO HEALTH INC (OPK) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into OPK?

As of Q1 2026, tracked institutions in OPKO HEALTH INC show 60 buyers versus 51 sellers — net inflows.

OPKO HEALTH INC

OPK·68375N103·US·Common Stock·Healthcare - Diagnostics & Research-Activist

119

Holders

Avg rating(31 Elite)

$154.8M

Total Value

54% (131)

Fund Consensus

60 buying - 51 selling

Smart Money Verdict

View all

Held by 119 funds

31 elite

Who's Trading

ActivistFPFROST PHILLIP MD ET AL34.1%Jul 1, 2026

InsiderPAPAGANELLI JOHN ABuy $11KMar 20, 2026

InsiderFAFROST PHILLIP MD ET ALBuy $257KNov 21, 2025

InsiderFAFROST PHILLIP MD ET ALBuy $255KNov 21, 2025

InsiderFAFROST PHILLIP MD ET ALBuy $118KNov 21, 2025

InsiderFAFROST PHILLIP MD ET ALBuy $5KNov 21, 2025

InsiderFAFROST PHILLIP MD ET ALBuy $133KNov 21, 2025

InsiderFAFROST PHILLIP MD ET ALBuy $18KNov 20, 2025

InsiderFAFROST PHILLIP MD ET ALBuy $2KNov 20, 2025

ActivistFPFROST PHILLIP MD ET AL32.8%Oct 1, 2025

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	36.2M(+4.0%)	$41.3M	0.0%	-5.96%	30
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	14.8M	$16.8M	0.0%	+13.45%	39
VAVANGUARD CAPITAL MANAGEMENT LLC	New	14.5M	$16.5M	0.0%	+13.45%	39
GEODE CAPITAL MANAGEMENT, LLC	Increased	11.3M(+2.2%)	$12.9M	0.0%	-40.81%	29
STATE STREET CORP	Increased	9.5M(+6.1%)	$10.8M	0.0%	-7.36%	30
GOLDMAN SACHS GROUP INC	Increased	7.7M(+28.2%)	$8.7M	0.0%	+1.38%	34
UBS Group AG	Increased	6.1M(+13.4%)	$6.9M	0.0%	-1.55%	31
NORTHERN TRUST CORP	Increased	3.6M(+5.3%)	$4.1M	0.0%	-43.42%	28
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	3.6M(-3.2%)	$4.1M	0.0%	-38.96%	0
VFVANGUARD FIDUCIARY TRUST CO	New	2.7M	$3.1M	0.0%	+13.45%	37
CITADEL ADVISORS LLC	Decreased	2.1M(-27.2%)	$2.4M	0.0%	+2.14%	0
DIMENSIONAL FUND ADVISORS LP	Decreased	1.6M(-3.2%)	$1.8M	0.0%	-4.74%	0
Bank of New York Mellon Corp	Decreased	1.3M(-2.3%)	$1.5M	0.0%	-59.12%	0
MORGAN STANLEY	Increased	1.2M(+30.4%)	$1.4M	0.0%	-3.91%	32
VOYA INVESTMENT MANAGEMENT LLC	Increased	1.2M(+5.3%)	$1.3M	0.0%	-9.64%	27
BANK OF AMERICA CORP /DE/	Increased	1.1M(+84.7%)	$1.3M	0.0%	-6.81%	39
JANE STREET GROUP, LLC	Decreased	1.1M(-37.2%)	$1.3M	0.0%	+3.01%	0
Nuveen, LLC	Increased	846,993(+0.6%)	$965,572	0.0%	-20.44%	25
Swiss National Bank	Unchanged	845,755	$964,161	0.0%	-42.50%	0
Invesco Ltd.	Increased	793,169(+1.5%)	$904,214	0.0%	-2.81%	25