Oruka Therapeutics, Inc. (ORKA) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling ORKA?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Oruka Therapeutics, Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on ORKA?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Oruka Therapeutics, Inc..

Is institutional money flowing into ORKA?

83 institutional investors hold Oruka Therapeutics, Inc. (ORKA). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about ORKA?

Track institutional sentiment and conviction scores for Oruka Therapeutics, Inc. (ORKA) including Smart Money Verdict and position changes on HoldingsIntel.

Oruka Therapeutics, Inc.

ORKA·687604108·US·equity·Healthcare - Biotechnology-Activist

ORKA (Oruka Therapeutics, Inc.) is held by 83 institutional investors as of Q4 2025. Largest holders: FMR LLC ($220.1M), BlackRock, Inc. ($107.3M), VIKING GLOBAL INVESTORS LP ($80.8M). Net institutional sentiment: Bullish.

Holders

Avg rating(4 Elite)

$938.7M

Total Value

84% (88)

Fund Consensus

67 buying - 13 selling

Smart Money VerdictView all

54Mixed MomentumSplit Signals

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See how ORKA's score breaks down across 4 SEC sources

Held by 83 funds

4 elite

Who's Trading

InsiderGoncalves JoanaSell $278KApr 15, 2026

Activist

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	7.3M(+0.1%)	$220.1M	0.0%	+73.49%	31
BlackRock, Inc.	Increased	3.5M(+60.5%)	$107.3M	0.0%	+63.82%	43
VIKING GLOBAL INVESTORS LP	Unchanged	2.7M	$80.8M	0.2%	+70.24%	0
VANGUARD GROUP INC	Increased	2.5M(+38.1%)	$74.4M	0.0%	+55.04%	39
RTW INVESTMENTS, LP	Increased	2.1M(+5.8%)	$62.4M	0.6%	+42.82%	44
STATE STREET CORP	Increased	1.4M(+112.2%)	$41.9M	0.0%	+46.07%	47
Avoro Capital Advisors LLC	Unchanged	1.3M	$40.4M	0.4%	+70.24%	0
Blackstone Inc.	Increased	1.2M(+37.0%)	$35.3M	0.1%	+78.41%	45
Polar Capital Holdings Plc	Decreased	978,288(-5.2%)	$29.7M	0.1%	+104.38%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	942,507(+36.6%)	$28.6M	0.0%	+74.93%	38
FRANKLIN RESOURCES INC	Decreased	938,421(-11.9%)	$28.4M	0.0%	+69.01%	0
MERCER GLOBAL ADVISORS INC /ADV	Decreased	745,277(-12.6%)	$22.6M	0.0%	+196.37%	0
CITADEL ADVISORS LLC	Increased	726,118(+129.1%)	$22M	0.0%	+32.26%	46
Point72 Asset Management, L.P.	Decreased	600,000(-42.1%)	$18.2M	0.0%	+60.85%	0
Woodline Partners LP	Increased	574,553(+0.0%)	$17.4M	0.1%	+51.34%	28
Candriam S.C.A.	Increased	400,509(+9.1%)	$12.1M	0.1%	+81.09%	30
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	329,496(+33.4%)	$10M	0.0%	+63.93%	36
NORTHERN TRUST CORP	Increased	280,904(+27.9%)	$8.5M	0.0%	+97.11%	34
UBS Group AG	Increased	271,013(+213.1%)	$8.2M	0.0%	+37.03%	44
BARCLAYS PLC	Increased	173,329(+81.8%)	$5.3M	0.0%	+44.11%	42
Invesco Ltd.	Increased	143,121(+777.1%)	$4.3M	0.0%	+21.09%	43
BANK OF AMERICA CORP /DE/	Increased	139,272(+76.3%)	$4.2M	0.0%	+46.01%	41
MORGAN STANLEY	Decreased	122,198(-9.4%)	$3.7M	0.0%	+82.83%	0
DEUTSCHE BANK AG\	Increased	119,329(+439.5%)	$3.6M	0.0%	+26.47%	43
Bank of New York Mellon Corp	Increased	114,173(+61.6%)	$3.5M	0.0%	+77.78%	38
Alyeska Investment Group, L.P.	New	100,000	$3M	0.0%	+12.77%	37
GOLDMAN SACHS GROUP INC	Increased	92,995(+370.3%)	$2.8M	0.0%	+28.35%	42
Nuveen, LLC	Increased	86,347(+144.5%)	$2.6M	0.0%	+51.04%	42
WELLINGTON MANAGEMENT GROUP LLP	Decreased	84,716(-7.0%)	$2.6M	0.0%	+70.24%	0
TD ASSET MANAGEMENT INC	Increased	79,896(+74.2%)	$2.4M	0.0%	+28.74%	39
D. E. Shaw & Co., Inc.	Decreased	76,415(-19.9%)	$2.3M	0.0%	+143.81%	0
Aberdeen Group plc	Unchanged	75,680	$2.3M	0.0%	+196.39%	0
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Increased	61,358(+18.2%)	$1.8M	0.0%	+50.34%	30
MILLENNIUM MANAGEMENT LLC	New	58,723	$1.8M	0.0%	+12.77%	36
AMERICAN CENTURY COMPANIES INC	Increased	57,080(+67.3%)	$1.7M	0.0%	+41.27%	38
WELLS FARGO & COMPANY/MN	Increased	43,261(+107.4%)	$1.3M	0.0%	+55.87%	41
Swiss National Bank	New	43,000	$1.3M	0.0%	+12.77%	35
VOYA INVESTMENT MANAGEMENT LLC	New	42,503	$1.3M	0.0%	+12.77%	35
RHUMBLINE ADVISERS	Increased	41,017(+35.3%)	$1.2M	0.0%	+103.55%	33
ALPS ADVISORS INC	New	39,751	$1.2M	0.0%	+12.77%	35
Rafferty Asset Management, LLC	Increased	38,485(+201.0%)	$1.2M	0.0%	+27.02%	41
ALLIANCEBERNSTEIN L.P.	New	37,800	$1.1M	0.0%	+12.77%	35
Verition Fund Management LLC	New	35,710	$1.1M	0.0%	+12.77%	35
TWO SIGMA INVESTMENTS, LP	Unchanged	28,566	$865,835	0.0%	+172.79%	0
SCHRODER INVESTMENT MANAGEMENT GROUP	Unchanged	29,184	$849,838	0.0%	+70.24%	0
Squarepoint Ops LLC	New	27,671	$838,708	0.0%	+12.77%	34
STATE OF WISCONSIN INVESTMENT BOARD	New	22,968	$696,160	0.0%	+12.77%	34
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	21,658(+1175.5%)	$656,454	0.0%	+18.53%	40
MetLife Investment Management, LLC	Increased	21,362(+29.4%)	$647,482	0.0%	+116.41%	31
JPMORGAN CHASE & CO	Increased	20,417(+41.0%)	$618,839	0.0%	+91.35%	22
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	20,152(+53.3%)	$608,135	0.0%	+89.23%	34
Hudson Bay Capital Management LP	New	20,000	$606,200	0.0%	+12.77%	34
GLENMEDE TRUST CO NA	New	19,485	$590,590	0.0%	+12.77%	34
Legal & General Group Plc	Increased	18,744(+656.7%)	$568,131	0.0%	+22.83%	39
ENVESTNET ASSET MANAGEMENT INC	New	15,247	$462,137	0.0%	+12.77%	33
INTECH INVESTMENT MANAGEMENT LLC	Increased	14,813(+18.4%)	$448,982	0.0%	+136.44%	28
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	New	14,244	$431,736	0.0%	+12.77%	33
JANUS HENDERSON GROUP PLC	New	12,100	$366,812	0.0%	+12.77%	33
Allianz Asset Management GmbH	New	10,300	$312,193	0.0%	+12.77%	32
Police & Firemen's Retirement System of New Jersey	Increased	10,207(+38.7%)	$309,374	0.0%	+91.81%	31
CITIGROUP INC	Increased	9,828(+191.6%)	$297,887	0.0%	+40.59%	38
SEI INVESTMENTS CO	New	9,676	$293,280	0.0%	+12.77%	32
Brevan Howard Capital Management LP	New	9,416	$285,399	0.0%	+12.77%	32
ProShare Advisors LLC	New	9,189	$278,519	0.0%	+12.77%	32
SUSQUEHANNA INTERNATIONAL GROUP, LLP	New	8,665	$262,636	0.0%	+12.77%	36
NEW YORK STATE COMMON RETIREMENT FUND	Unchanged	8,600	$260,666	0.0%	+196.39%	0
KLP KAPITALFORVALTNING AS	New	8,000	$242,480	0.0%	+12.77%	32
Creative Planning	New	7,696	$233,266	0.0%	+12.77%	32
BNP PARIBAS FINANCIAL MARKETS	Increased	5,892(+2.5%)	$178,587	0.0%	+101.99%	23
Russell Investments Group, Ltd.	Increased	3,041(+35.0%)	$92,172	0.0%	+50.39%	28
US BANCORP \DE\	Increased	2,925(+1543.3%)	$88,657	0.0%	+15.14%	35
Mirae Asset Global Investments Co., Ltd.	Increased	2,352(+62.4%)	$71,289	0.0%	+49.44%	31
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	1,450(-28.0%)	$43,950	0.0%	+70.24%	0
LOS ANGELES CAPITAL MANAGEMENT LLC	New	1,302	$36,599	0.0%	+12.77%	28
ROYAL BANK OF CANADA	Increased	1,139(+47.2%)	$34,000	0.0%	+94.52%	18
PRICE T ROWE ASSOCIATES INC /MD/	Increased	649,346(+3.6%)	$19,683	0.0%	+64.75%	19
BALYASNY ASSET MANAGEMENT L.P.	New	536	$16,246	0.0%	+12.77%	28
NISA INVESTMENT ADVISORS, LLC	New	282	$8,547	0.0%	+12.77%	25
GROUP ONE TRADING LLC	Increased	200(+100.0%)	$6,062	0.0%	+35.67%	17
Allworth Financial LP	Increased	114(+2180.0%)	$3,456	0.0%	+15.92%	15
Farther Finance Advisors, LLC	Unchanged	10	$303	0.0%	+70.24%	0
OSAIC HOLDINGS, INC.	Increased	4(+300.0%)	$121	0.0%	+33.44%	12
CIBC Private Wealth Group LLC	Unchanged	1	$30	0.0%	+70.24%	0
Caption Management, LLC	Exited	0(-100.0%)	$38,460	0.0%	+50.96%	0
TORONTO DOMINION BANK	Exited	0(-100.0%)	$1.1M	0.0%	+53.67%	0
SIMPLEX TRADING, LLC	Exited	0(-100.0%)	$14	0.0%	+50.96%	0
Jefferies Financial Group Inc.	Exited	0(-100.0%)	$1.2M	0.0%	+61.11%	0
NATIONAL BANK OF CANADA /FI/	Exited	0(-100.0%)	$153	0.0%	+53.67%	0

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