ORUKA THERAPEUTICS INC (ORKA) is held by 102 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is FMR LLC as of Q1 2026.

Are institutions buying or selling ORKA?

In Q1 2026, 74 institutions opened or increased positions in ORUKA THERAPEUTICS INC while 28 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on ORKA?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for ORUKA THERAPEUTICS INC.

How many hedge funds hold ORKA?

102 institutional investors report holding ORUKA THERAPEUTICS INC (ORKA) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into ORKA?

As of Q1 2026, tracked institutions in ORUKA THERAPEUTICS INC show 74 buyers versus 28 sellers — net inflows.

ORUKA THERAPEUTICS INC

ORKA·687604108·US·Common Stock·Healthcare - Biotechnology-Activist

102

Holders

(11 Elite)

$1.5B

Total Value

73% (102)

Consensus

74 buying - 28 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Held by 102 funds

11 elite

Who's Trading

ActivistFAFairmount Funds Management LLC19.5%Jul 1, 2026

ActivistFAFairmount Funds Management LLC20.0%May 4, 2026

InsiderSLSandler Laura LeeExercise 5K shMay 1, 2026

InsiderSLSandler Laura LeeSell $138KMay 1, 2026

InsiderSLSandler Laura LeeSell $115KMay 1, 2026

InsiderSLSandler Laura LeeSell $20KMay 1, 2026

InsiderSLSandler Laura LeeSell $26KMay 1, 2026

InsiderSLSandler Laura LeeSell $13KMay 1, 2026

InsiderSLSandler Laura LeeSell $7KMay 1, 2026

InsiderGJGoncalves JoanaSell $278KApr 15, 2026

View all insider trades View all activist filings

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	7.4M(+2.3%)	$364.5M	0.0%	+350.92%	32
BlackRock, Inc.	Decreased	3.5M(-0.3%)	$173M	0.0%	+332.95%	0
VIKING GLOBAL INVESTORS LP	Unchanged	2.7M	$130.8M	0.4%	+349.92%	0
RTW INVESTMENTS, LP	Unchanged	2.1M	$101M	1.0%	+277.43%	0
VAVANGUARD CAPITAL MANAGEMENT LLC	New	1.9M	$91.2M	0.0%	+164.28%	41
STATE STREET CORP	Increased	1.6M(+16.6%)	$79.1M	0.0%	+262.29%	34
Polar Capital Holdings Plc	Increased	1M(+7.1%)	$51.4M	0.2%	+405.21%	38
CITADEL ADVISORS LLC	Increased	1M(+38.8%)	$49.4M	0.0%	+220.64%	39
FRANKLIN RESOURCES INC	Increased	1M(+7.0%)	$49.2M	0.0%	+327.38%	31
GEODE CAPITAL MANAGEMENT, LLC	Increased	954,867(+1.3%)	$46.8M	0.0%	+357.86%	30
MGMERCER GLOBAL ADVISORS INC /ADV	Increased	802,470(+7.7%)	$39.4M	0.1%	+587.09%	31
PRICE T ROWE ASSOCIATES INC /MD/	Increased	727,449(+12.0%)	$35.7M	0.0%	+307.10%	32
Woodline Partners LP	Increased	574,882(+0.1%)	$28.2M	0.1%	+299.85%	34
Candriam S.C.A.	Increased	411,006(+2.6%)	$20.2M	0.1%	+368.89%	35
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	350,892	$17.2M	0.0%	+164.28%	39
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	321,949(-2.3%)	$15.8M	0.0%	+333.23%	0
WESTFIELD CAPITAL MANAGEMENT CO LP	New	313,130	$15.4M	0.1%	+164.28%	39
NORTHERN TRUST CORP	Increased	299,044(+6.5%)	$14.7M	0.0%	+391.94%	30
VFVANGUARD FIDUCIARY TRUST CO	New	257,071	$12.6M	0.0%	+164.28%	39
GOLDMAN SACHS GROUP INC	Increased	246,711(+165.3%)	$12.1M	0.0%	+188.29%	45