Vaxcyte, Inc. (PCVX) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling PCVX?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Vaxcyte, Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on PCVX?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Vaxcyte, Inc..

Is institutional money flowing into PCVX?

153 institutional investors hold Vaxcyte, Inc. (PCVX). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about PCVX?

Track institutional sentiment and conviction scores for Vaxcyte, Inc. (PCVX) including Smart Money Verdict and position changes on HoldingsIntel.

Vaxcyte, Inc.

PCVX·92243G108·US·equity·Healthcare - Biotechnology-13D/G

PCVX (Vaxcyte, Inc.) is held by 153 institutional investors as of Q4 2025. Largest holders: FMR LLC ($638.3M), JANUS HENDERSON GROUP PLC ($617.7M), VANGUARD GROUP INC ($562.6M). Net institutional sentiment: Mixed.

153

Holders

Avg rating(12 Elite)

$5.1B

Total Value

45% (173)

Fund Consensus

74 buying - 90 selling

Smart Money VerdictView all

52Mixed MomentumSplit Signals

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See how PCVX's score breaks down across 4 SEC sources

Held by 153 funds

12 elite

Who's Trading

InsiderCowan ElviaSell $180KApr 7, 2026

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	13.8M(+10.6%)	$638.3M	0.0%	-22.57%	35
JANUS HENDERSON GROUP PLC	Increased	13.4M(+2.2%)	$617.7M	0.3%	+15.44%	38
VANGUARD GROUP INC	Decreased	12.2M(-1.0%)	$562.6M	0.0%	-45.36%	0
RA CAPITAL MANAGEMENT, L.P.	Decreased	10.7M(-10.4%)	$494.8M	5.1%	+21.91%	0
BlackRock, Inc.	Increased	10.2M(+2.9%)	$472.8M	0.0%	-25.85%	32
WELLINGTON MANAGEMENT GROUP LLP	Increased	6M(+18.6%)	$275.3M	0.0%	+10.44%	36
STATE STREET CORP	Increased	5M(+4.1%)	$229.8M	0.0%	-5.84%	32
D. E. Shaw & Co., Inc.	Decreased	3.6M(-15.4%)	$167.5M	0.1%	+40.88%	0
WESTFIELD CAPITAL MANAGEMENT CO LP	Decreased	3.5M(-5.2%)	$163.3M	0.7%	+13.75%	0
GEODE CAPITAL MANAGEMENT, LLC	Decreased	2.9M(-0.6%)	$132.3M	0.0%	+11.57%	0
ADAGE CAPITAL PARTNERS GP, L.L.C.	Increased	1.7M(+418.0%)	$79.6M	0.1%	+38.05%	57
Polar Capital Holdings Plc	Increased	1.7M(+302.6%)	$77.2M	0.3%	-2.16%	57
MAVERICK CAPITAL LTD	Increased	1.4M(+5.0%)	$62.5M	0.7%	-23.24%	44
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	1.3M(+0.0%)	$59.7M	0.0%	-9.97%	29
UBS Group AG	Increased	1.1M(+29.0%)	$50.5M	0.0%	-3.47%	37
JPMORGAN CHASE & CO	Decreased	1.1M(-30.6%)	$50.1M	0.0%	-14.64%	0
GOLDMAN SACHS GROUP INC	Increased	1.1M(+10.5%)	$49.7M	0.0%	-22.02%	32
NORTHERN TRUST CORP	Decreased	1M(-3.6%)	$47.7M	0.0%	+12.33%	0
Aberdeen Group plc	Increased	979,765(+35.5%)	$45.2M	0.1%	+25.17%	38
Pictet Asset Management Holding SA	Decreased	881,435(-14.4%)	$40.7M	0.0%	-13.18%	0
Capital Research Global Investors	Unchanged	842,978	$38.9M	0.0%	-6.07%	0
MORGAN STANLEY	Increased	835,387(+6.5%)	$38.5M	0.0%	-17.92%	31
BANK OF AMERICA CORP /DE/	Increased	701,634(+10.5%)	$32.4M	0.0%	-5.20%	32
JENNISON ASSOCIATES LLC	Decreased	677,553(-42.1%)	$31.3M	0.0%	+25.94%	0
BROWN ADVISORY INC	Decreased	566,925(-16.3%)	$26.2M	0.0%	-19.47%	0
VICTORY CAPITAL MANAGEMENT INC	Increased	549,514(+74.5%)	$25.4M	0.0%	+42.13%	43
Assenagon Asset Management S.A.	Increased	544,728(+147.7%)	$25.1M	0.0%	+35.55%	46
Ensign Peak Advisors, Inc	Decreased	527,688(-0.2%)	$24.3M	0.0%	-5.09%	0
FEDERATED HERMES, INC.	Increased	523,489(+2783.3%)	$24.2M	0.0%	+32.83%	46
Bank of New York Mellon Corp	Increased	449,363(+2.2%)	$20.7M	0.0%	+36.85%	29
MILLENNIUM MANAGEMENT LLC	Decreased	424,294(-55.3%)	$19.6M	0.0%	+34.57%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Decreased	389,010(-2.3%)	$17.9M	0.0%	-19.77%	0
TD ASSET MANAGEMENT INC	Decreased	363,734(-8.7%)	$16.8M	0.0%	+14.80%	0
AMERICAN CENTURY COMPANIES INC	Increased	357,300(+3.9%)	$16.5M	0.0%	+3.16%	29
DEUTSCHE BANK AG\	Decreased	342,894(-13.8%)	$15.8M	0.0%	-26.30%	0
FRANKLIN RESOURCES INC	Increased	336,143(+0.0%)	$15.5M	0.0%	-8.25%	28
CITADEL ADVISORS LLC	Increased	326,574(+58.7%)	$15.1M	0.0%	+49.00%	40
Nuveen, LLC	Decreased	307,202(-36.6%)	$14.2M	0.0%	-13.88%	0
AMERIPRISE FINANCIAL INC	Decreased	305,194(-18.6%)	$14.1M	0.0%	-20.72%	0
Artisan Partners Limited Partnership	New	304,049	$14M	0.0%	+31.73%	39
BARCLAYS PLC	Decreased	296,195(-24.8%)	$13.7M	0.0%	+11.13%	0
JANE STREET GROUP, LLC	Decreased	279,604(-18.6%)	$12.9M	0.0%	+13.41%	0
Woodline Partners LP	Increased	274,740(+11.2%)	$12.7M	0.0%	-7.98%	31
Alyeska Investment Group, L.P.	Unchanged	244,775	$11.3M	0.0%	-31.06%	0
CITIGROUP INC	Decreased	241,880(-22.7%)	$11.2M	0.0%	-22.42%	0
Swiss National Bank	Increased	230,400(+2.4%)	$10.6M	0.0%	+22.86%	28
Qube Research & Technologies Ltd	Decreased	207,090(-62.6%)	$9.6M	0.0%	+83.61%	0
DIMENSIONAL FUND ADVISORS LP	Increased	191,786(+576.1%)	$8.8M	0.0%	+15.30%	44
RAYMOND JAMES FINANCIAL INC	Decreased	185,851(-1.8%)	$8.5M	0.0%	-24.98%	0
Point72 Asset Management, L.P.	Decreased	161,614(-76.8%)	$7.5M	0.0%	+72.64%	0
RHUMBLINE ADVISERS	Decreased	150,919(-17.6%)	$7M	0.0%	+24.44%	0
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	Decreased	144,603(-0.0%)	$6.7M	0.0%	-11.09%	0
Invesco Ltd.	Decreased	141,220(-21.1%)	$6.5M	0.0%	-14.32%	0
WELLS FARGO & COMPANY/MN	Increased	134,075(+6.4%)	$6.2M	0.0%	-1.36%	29
ALLIANCEBERNSTEIN L.P.	Decreased	133,882(-1.0%)	$6.2M	0.0%	+17.79%	0
Rafferty Asset Management, LLC	Decreased	133,764(-10.5%)	$6.2M	0.0%	+6.86%	0
Legal & General Group Plc	Decreased	120,301(-7.8%)	$5.6M	0.0%	+12.39%	0
NEW YORK STATE COMMON RETIREMENT FUND	Decreased	116,817(-4.1%)	$5.4M	0.0%	-2.19%	0
TWO SIGMA INVESTMENTS, LP	Increased	111,310(+3.5%)	$5.1M	0.0%	+79.20%	28
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	110,862(+1.3%)	$5.1M	0.0%	+25.47%	27
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	108,445(-20.8%)	$5M	0.0%	+10.07%	0
Creative Planning	Increased	102,686(+27.8%)	$4.7M	0.0%	+13.26%	33
BANQUE PICTET & CIE SA	Decreased	71,815(-4.1%)	$3.3M	0.0%	-0.58%	0
Universal- Beteiligungs- und Servicegesellschaft mbH	Increased	70,124(+105.3%)	$3.2M	0.0%	+4.21%	43
Man Group plc	Decreased	68,913(-71.9%)	$3.2M	0.0%	+46.85%	0
STATE OF WISCONSIN INVESTMENT BOARD	Decreased	68,285(-10.8%)	$3.2M	0.0%	+9.52%	0
RENAISSANCE TECHNOLOGIES LLC	Decreased	65,211(-19.0%)	$3M	0.0%	-3.52%	0
LAZARD ASSET MANAGEMENT LLC	Decreased	64,978(-45.4%)	$3M	0.0%	-25.59%	0
MetLife Investment Management, LLC	Decreased	63,807(-4.1%)	$2.9M	0.0%	+13.38%	0
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	61,015(+0.3%)	$2.8M	0.0%	-25.07%	26
INTECH INVESTMENT MANAGEMENT LLC	Decreased	58,234(-14.3%)	$2.7M	0.0%	-32.02%	0
FRED ALGER MANAGEMENT, LLC	Increased	57,808(+27.3%)	$2.7M	0.0%	+44.93%	33
ENVESTNET ASSET MANAGEMENT INC	Decreased	50,798(-27.2%)	$2.3M	0.0%	-5.11%	0
BNP PARIBAS FINANCIAL MARKETS	Decreased	50,762(-80.3%)	$2.3M	0.0%	+38.46%	0
VOYA INVESTMENT MANAGEMENT LLC	Increased	47,755(+41.3%)	$2.2M	0.0%	+7.70%	35
Zurcher Kantonalbank (Zurich Cantonalbank)	Increased	40,002(+3.2%)	$1.8M	0.0%	+13.15%	27
State of New Jersey Common Pension Fund D	Decreased	39,880(-40.2%)	$1.8M	0.0%	+30.47%	0
BROWN BROTHERS HARRIMAN & CO	Unchanged	38,033	$1.8M	0.0%	+220.58%	0
GUGGENHEIM CAPITAL LLC	Decreased	34,501(-2.6%)	$1.6M	0.0%	+44.06%	0
Brevan Howard Capital Management LP	Decreased	34,351(-48.8%)	$1.6M	0.0%	+81.52%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	34,116(-71.3%)	$1.6M	0.0%	-19.12%	0
Arizona State Retirement System	Decreased	32,800(-4.5%)	$1.5M	0.0%	+17.54%	0
Police & Firemen's Retirement System of New Jersey	Decreased	31,122(-2.8%)	$1.4M	0.0%	-19.19%	0
SEI INVESTMENTS CO	Decreased	30,940(-65.6%)	$1.4M	0.0%	+26.57%	0
Alberta Investment Management Corp	New	30,100	$1.4M	0.0%	+31.73%	35
BALYASNY ASSET MANAGEMENT L.P.	Decreased	26,865(-90.3%)	$1.2M	0.0%	+76.62%	0
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	26,738	$1.2M	0.0%	+19.76%	0
ProShare Advisors LLC	Increased	26,725(+10.4%)	$1.2M	0.0%	-11.22%	28
Vanguard Personalized Indexing Management, LLC	Increased	25,224(+59.1%)	$1.2M	0.0%	+18.93%	36
KLP KAPITALFORVALTNING AS	Increased	25,000(+1.6%)	$1.2M	0.0%	-23.30%	26
Mirae Asset Global Investments Co., Ltd.	Increased	24,579(+6.0%)	$1.1M	0.0%	+35.92%	27
Pathstone Holdings, LLC	Increased	24,229(+9.7%)	$1.1M	0.0%	-11.61%	28
LOS ANGELES CAPITAL MANAGEMENT LLC	Decreased	22,007(-18.2%)	$984,815	0.0%	+83.61%	0
LPL Financial LLC	Increased	20,489(+6.1%)	$945,362	0.0%	+18.94%	27
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	New	20,000	$923,000	0.0%	+31.73%	35
TEACHER RETIREMENT SYSTEM OF TEXAS	Decreased	17,291(-39.3%)	$797,807	0.0%	+3.65%	0
DnB Asset Management AS	Increased	16,471(+46.6%)	$759,972	0.0%	-4.13%	34
Russell Investments Group, Ltd.	Decreased	16,455(-3.0%)	$759,256	0.0%	-29.07%	0
PRUDENTIAL FINANCIAL INC	Decreased	16,425(-15.6%)	$757,850	0.0%	-13.96%	0
GILDER GAGNON HOWE & CO LLC	Decreased	16,109(-0.2%)	$743,269	0.0%	+24.20%	0
Verition Fund Management LLC	Decreased	15,731(-62.4%)	$725,828	0.0%	-17.24%	0
XTX Topco Ltd	New	15,261	$704,143	0.0%	+31.73%	34
PNC FINANCIAL SERVICES GROUP, INC.	Increased	14,917(+3.6%)	$688,272	0.0%	+15.80%	25
Walleye Capital LLC	New	14,805	$683,103	0.0%	+31.73%	34
AQR CAPITAL MANAGEMENT LLC	New	14,762	$681,119	0.0%	+31.73%	34
Quantinno Capital Management LP	Increased	14,501(+17.3%)	$669,076	0.0%	+73.53%	29
Baird Financial Group, Inc.	Decreased	13,788(-6.3%)	$636,178	0.0%	-7.34%	0
CANADA PENSION PLAN INVESTMENT BOARD	New	10,400	$479,856	0.0%	+31.73%	33
STRS OHIO	Decreased	10,300(-14.2%)	$475,242	0.0%	-2.77%	0
ROYAL BANK OF CANADA	Decreased	9,224(-99.0%)	$426,000	0.0%	+74.19%	0
XPONANCE LLC	Increased	9,080(+0.8%)	$418,951	0.0%	-2.94%	24
Vident Advisory, LLC	Increased	8,821(+12.9%)	$407,001	0.0%	+75.71%	27
Mariner, LLC	Increased	8,539(+10.1%)	$393,906	0.0%	+67.86%	26
Sumitomo Mitsui Trust Group, Inc.	Decreased	8,284(-0.7%)	$382,224	0.0%	+72.64%	0
HSBC HOLDINGS PLC	Decreased	7,798(-84.6%)	$363,399	0.0%	+19.59%	0
Cetera Investment Advisers	Decreased	7,797(-8.3%)	$359,754	0.0%	-6.06%	0
CIBC Private Wealth Group LLC	Increased	7,756(+472.0%)	$357,862	0.0%	+37.43%	38
CIBC WORLD MARKETS CORP	Decreased	7,575(-51.1%)	$349,511	0.0%	-19.97%	0
Allianz Asset Management GmbH	New	7,100	$327,594	0.0%	+31.73%	33
MACKENZIE FINANCIAL CORP	Decreased	7,174(-10.4%)	$325,130	0.0%	+83.61%	0
Allspring Global Investments Holdings, LLC	New	5,850	$271,791	0.0%	+31.73%	32
Swiss Life Asset Management Ltd	New	5,399	$249,110	0.0%	+31.73%	32
Amundi	New	5,090	$234,853	0.0%	+31.73%	32
FARALLON CAPITAL MANAGEMENT LLC	New	5,000	$230,700	0.0%	+31.73%	32
PRINCIPAL FINANCIAL GROUP INC	Decreased	4,932(-38.3%)	$227,562	0.0%	-23.48%	0
Sanctuary Advisors, LLC	New	4,669	$215,428	0.0%	+31.73%	32
Empowered Funds, LLC	New	4,576	$211,137	0.0%	+31.73%	32
CIBC Asset Management Inc	New	4,516	$208,368	0.0%	+31.73%	32
Neuberger Berman Group LLC	New	4,399	$202,970	0.0%	+31.73%	32
OSAIC HOLDINGS, INC.	Decreased	3,441(-19.5%)	$158,765	0.0%	-5.97%	0
NISA INVESTMENT ADVISORS, LLC	Decreased	3,114(-4.3%)	$143,680	0.0%	+18.05%	0
DANSKE BANK A/S	Unchanged	2,100	$96,894	0.0%	+65.74%	0
ASSETMARK, INC	Decreased	1,895(-85.8%)	$87,435	0.0%	-14.71%	0
SIMPLEX TRADING, LLC	New	1,549	$71,470	0.0%	+31.73%	32
US BANCORP \DE\	Increased	1,474(+24.3%)	$68,011	0.0%	+11.11%	26
Eurizon Capital SGR S.p.A.	New	1,383	$62,727	0.0%	+31.73%	29
Allworth Financial LP	Increased	1,257(+2.9%)	$57,998	0.0%	+62.29%	21
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	1.2M(-30.4%)	$54,232	0.0%	-15.00%	0
COMERICA BANK	Decreased	1,103(-99.8%)	$50,870	0.0%	+15.02%	0
Rockefeller Capital Management L.P.	Increased	995(+21.8%)	$45,909	0.0%	+63.55%	24
GROUP ONE TRADING LLC	New	831	$38,342	0.0%	+31.73%	28
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	Increased	495(+26.6%)	$22,840	0.0%	+2.66%	16
CULLEN/FROST BANKERS, INC.	Increased	406(+36.2%)	$18,733	0.0%	+11.78%	24
Mitsubishi UFJ Asset Management Co., Ltd.	Unchanged	372	$17,283	0.0%	-35.16%	0
HUNTINGTON NATIONAL BANK	Unchanged	369	$17,025	0.0%	-4.56%	0
Farther Finance Advisors, LLC	Increased	343(+55.2%)	$15,826	0.0%	+23.79%	26
Optiver Holding B.V.	Decreased	336(-47.4%)	$15,503	0.0%	+14.44%	0
Federation des caisses Desjardins du Quebec	Increased	192(+81.1%)	$8,859	0.0%	-16.25%	17
HRT FINANCIAL LP	Decreased	113,950(-0.1%)	$5,257	0.0%	+72.64%	0
JONES FINANCIAL COMPANIES LLLP	Unchanged	110	$5,075	0.0%	-21.79%	0
BNP Paribas Asset Management Holding S.A.	New	1,636	$75	0.0%	+31.73%	15
Quadrature Capital Ltd	Exited	0(-100.0%)	$929,568	0.0%	+39.38%	0
Trexquant Investment LP	Exited	0(-100.0%)	$4.3M	0.0%	+38.38%	0
STIFEL FINANCIAL CORP	Exited	0(-100.0%)	$608,175	0.0%	-5.24%	0
NATIONAL BANK OF CANADA /FI/	Exited	0(-100.0%)	$468	0.0%	+31.05%	0
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	Exited	0(-100.0%)	$4.9M	0.0%	+31.05%	0
CI INVESTMENTS INC.	Exited	0(-100.0%)	$50	0.0%	-54.00%	0
ALPS ADVISORS INC	Exited	0(-100.0%)	$2.2M	0.0%	+39.38%	0
MACQUARIE GROUP LTD	Exited	0(-100.0%)	$2.9M	0.0%	-46.00%	0
NOMURA ASSET MANAGEMENT CO LTD	Unchanged	0	$0	0.0%	-47.13%	0
Orion Porfolio Solutions, LLC	Exited	0(-100.0%)	$355,200	0.0%	-34.45%	0
VOLORIDGE INVESTMENT MANAGEMENT, LLC	Exited	0(-100.0%)	$18.7M	0.0%	+39.38%	0
GLENMEDE TRUST CO NA	Exited	0(-100.0%)	$251,632	0.0%	-12.32%	0
SCHRODER INVESTMENT MANAGEMENT GROUP	Exited	0(-100.0%)	$2.8M	0.0%	-32.77%	0
Schonfeld Strategic Advisors LLC	Exited	0(-100.0%)	$1M	0.0%	-35.06%	0
Jain Global LLC	Exited	0(-100.0%)	$307,359	0.0%	+39.38%	0
Engineers Gate Manager LP	Exited	0(-100.0%)	$4.1M	0.0%	-24.57%	0
CAPSTONE INVESTMENT ADVISORS, LLC	Exited	0(-100.0%)	$439,264	0.0%	+31.05%	0
Fiera Capital Corp	Exited	0(-100.0%)	$12.5M	0.0%	-34.62%	0
Bridgewater Associates, LP	Exited	0(-100.0%)	$427,017	0.0%	+31.05%	0
TUDOR INVESTMENT CORP ET AL	Exited	0(-100.0%)	$2.6M	0.0%	+37.00%	0
BAKER BROS. ADVISORS LP	Exited	0(-100.0%)	$23.1M	0.0%	-33.04%	0

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