PYXIS ONCOLOGY INC (PYXS) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling PYXS?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for PYXIS ONCOLOGY INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on PYXS?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for PYXIS ONCOLOGY INC.

Is institutional money flowing into PYXS?

7 institutional investors hold PYXIS ONCOLOGY INC (PYXS). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about PYXS?

Track institutional sentiment and conviction scores for PYXIS ONCOLOGY INC (PYXS) including Smart Money Verdict and position changes on HoldingsIntel.

PYXIS ONCOLOGY INC

PYXS·747324101·US·equity·Healthcare - Biotechnology-Activist

PYXS (PYXIS ONCOLOGY INC) is held by 7 institutional investors as of Q1 2026. Largest holders: RENAISSANCE TECHNOLOGIES LLC ($1.3M), BlackRock, Inc. ($1.2M), GEODE CAPITAL MANAGEMENT, LLC ($873,815). Net institutional sentiment: Bearish.

Holders

Avg rating(6 Elite)

$524,217

Total Value

25% (9)

Fund Consensus

2 buying - 6 selling

Smart Money Verdict

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41Weak MomentumConfirmed

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See how PYXS's score breaks down across 4 SEC sources

Held by 7 funds

6 elite

Who's Trading

ActivistLALaurion Capital Management LP

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RENAISSANCE TECHNOLOGIES LLC	Increased	888,680(+22.0%)	$1.3M	0.0%	—	31
BlackRock, Inc.	Increased	788,839(+0.6%)	$1.2M	0.0%	—	17
GEODE CAPITAL MANAGEMENT, LLC	Increased	598,121(+3.6%)	$873,815	0.0%	—	26
JACOBS LEVY EQUITY MANAGEMENT, INC	New	460,997	$673,056	0.0%	—	34
MILLENNIUM MANAGEMENT LLC	Decreased	397,625(-46.5%)	$580,533	0.0%	—	0
MWMARSHALL WACE, LLP	Decreased	354,417(-9.1%)	$517,448	0.0%	—	0
JANE STREET GROUP, LLC	Decreased	304,459(-61.3%)	$444,510	0.0%	—	0
UBS Group AG	Decreased	254,124(-35.3%)	$371,021	0.0%	-12.07%	0
STATE STREET CORP	Increased	248,837(+3.0%)	$363,302	0.0%	—	17
XTX Topco Ltd	Decreased	200,096(-30.8%)	$292,140	0.0%	—	0
Bank of New York Mellon Corp	Decreased	133,996(-18.8%)	$195,634	0.0%	—	0
NewEdge Wealth, LLC	Unchanged	116,006	$169,369	0.0%	—	0
NORTHERN TRUST CORP	Unchanged	101,948	$148,844	0.0%	—	0
TWO SIGMA INVESTMENTS, LP	Decreased	73,300(-30.5%)	$107,018	0.0%	—	0
MORGAN STANLEY	Decreased	69,688(-21.9%)	$101,744	0.0%	—	0
PANAGORA ASSET MANAGEMENT INC	New	69,424	$101,359	0.0%	—	30
CITADEL ADVISORS LLC	Decreased	61,249(-74.9%)	$89,424	0.0%	—	0
STIFEL FINANCIAL CORP	New	50,537	$73,784	0.0%	—	29
TORONTO DOMINION BANK	Decreased	50,000(-33.3%)	$73,000	0.0%	—	0
BARCLAYS PLC	Decreased	49,825(-17.5%)	$72,745	0.0%	—	0
GOLDMAN SACHS GROUP INC	Decreased	46,920(-45.5%)	$68,503	0.0%	—	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	41,201(-62.0%)	$60,153	0.0%	—	0
COMMONWEALTH EQUITY SERVICES, LLC	Decreased	34,755(-12.6%)	$50,740	0.0%	-15.21%	0
LPL Financial LLC	Decreased	33,554(-4.4%)	$48,989	0.0%	-18.48%	0
Point72 Asset Management, L.P.	Decreased	32,006(-83.0%)	$46,729	0.0%	—	0
Cetera Investment Advisers	Unchanged	27,260	$39,800	0.0%	—	0
DIMENSIONAL FUND ADVISORS LP	Decreased	25,912(-48.2%)	$37,832	0.0%	-19.80%	0
Squarepoint Ops LLC	New	17,537	$25,604	0.0%	—	29
OSAIC HOLDINGS, INC.	Decreased	13,721(-20.3%)	$20,032	0.0%	—	0
FMR LLC	Decreased	11,912(-7.4%)	$17,392	0.0%	—	0
Qube Research & Technologies Ltd	Decreased	11,286(-92.3%)	$16,478	0.0%	—	0
PNC FINANCIAL SERVICES GROUP, INC.	New	6,500	$9,490	0.0%	+3.50%	26
ROYAL BANK OF CANADA	Decreased	5,839(-89.5%)	$9,000	0.0%	—	0
JPMORGAN CHASE & CO	Decreased	5,173(-6.2%)	$6,570	0.0%	—	0
Mirae Asset Global Investments Co., Ltd.	Increased	3,248(+7.3%)	$4,742	0.0%	+5.50%	11
FEDERATED HERMES, INC.	Increased	3,181(+68.0%)	$4,644	0.0%	—	15
CITIGROUP INC	Decreased	1,740(-40.0%)	$2,540	0.0%	—	0
BNP PARIBAS FINANCIAL MARKETS	Decreased	1,654(-93.2%)	$2,415	0.0%	—	0
NISA INVESTMENT ADVISORS, LLC	Unchanged	961	$1,403	0.0%	+36.09%	0
BALYASNY ASSET MANAGEMENT L.P.	Decreased	743(-91.0%)	$1,085	0.0%	—	0
JONES FINANCIAL COMPANIES LLLP	Unchanged	500	$655	0.0%	—	0
WELLS FARGO & COMPANY/MN	Decreased	285(-87.5%)	$416	0.0%	—	0
SIMPLEX TRADING, LLC	Decreased	253(-97.4%)	$369	0.0%	—	0
TWO SIGMA ADVISERS, LP	Exited	0(-100.0%)	$26,018	0.0%	—	0
ExodusPoint Capital Management, LP	Exited	0(-100.0%)	$365,434	0.0%	—	0
Quadrature Capital Ltd	Exited	0(-100.0%)	$115,616	0.0%	—	0
Jefferies Financial Group Inc.	Exited	0(-100.0%)	$18,400	0.0%	+31.19%	0
EGEngineers Gate Manager LP	Exited	0(-100.0%)	$26,238	0.0%	—	0
AMERICAN CENTURY COMPANIES INC	Exited	0(-100.0%)	$36,726	0.0%	—	0
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	Exited	0(-100.0%)	$14	0.0%	-8.33%	0
$US BANCORP \DE\$ US BANCORP \DE\	Exited	0(-100.0%)	$108	0.0%	—	0
HRT FINANCIAL LP	Exited	0(-100.0%)	$45,000	0.0%	—	0
OMERS ADMINISTRATION Corp	Exited	0(-100.0%)	$77,050	0.0%	—	0

PYXIS ONCOLOGY INC

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