PYXIS ONCOLOGY INC

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PYXS·747324101·US·Common Stock·Healthcare - Biotechnology-Activist

PYXS (PYXIS ONCOLOGY INC) is held by 48 institutional investors as of Q1 2026. Largest holders: VANGUARD CAPITAL MANAGEMENT LLC ($3M), RENAISSANCE TECHNOLOGIES LLC ($1.3M), BlackRock, Inc. ($1.2M). Net institutional sentiment: Bearish.

48

Holders

(7 Elite)

$11.7M

Total Value

27% (51)

Consensus

14 buying - 37 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Institutional (13F)53

Insider (Form 4)61

Activist (13D/13G)49

Congressional (STOCK Act)38

Holder Quality

37

★★★★★

Elite

25

★★★★

Strong

45

★★★

Solid

83

★★

Below

42

★

Weak

Held by 48 funds

7 elite

Who's Trading

Source dates: Price Aug 13, 2026 · Insiders Mar 25, 2026 · Activists Jul 10, 2026 · Congress none

ActivistBLBVF PARTNERS L P/IL10.0%Jul 10, 2026

ActivistGGGordonMD Global Investments LP12.1%Jul 2, 2026

ActivistLALaurion Capital Management LP7.7%Feb 9, 2026

ActivistMillennium Management LLC1.3%Oct 14, 2025

ActivistGGGordonMD Global Investments LP6.2%Sep 23, 2025

ActivistBlackRock, Inc.1.5%Jul 17, 2025

ActivistICIntegrated Core Strategies (US) LLC4.0%May 6, 2025

InsiderHRHUMPHREY RACHELSell $14KApr 21, 2025

InsiderHRHUMPHREY RACHELSell $194Apr 17, 2025

InsiderHRHUMPHREY RACHELSell $1KApr 14, 2025

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Top Holders

Top Holders (48)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
VAVANGUARD CAPITAL MANAGEMENT LLC	New	2M	$3M	0.0%	+110.49%	36
RENAISSANCE TECHNOLOGIES LLC	Increased	888,680(+22.0%)	$1.3M	0.0%	+86.38%	31
BlackRock, Inc.	Increased	788,839(+0.6%)	$1.2M	0.0%	+100.75%	17
GEODE CAPITAL MANAGEMENT, LLC	Increased	598,121(+3.6%)	$873,815	0.0%	-15.16%	26
JACOBS LEVY EQUITY MANAGEMENT, INC	New	460,997	$673,056	0.0%	+110.49%	34
MILLENNIUM MANAGEMENT LLC	Decreased	397,625(-46.5%)	$580,533	0.0%	+26.83%	0
MWMARSHALL WACE, LLP	Decreased	354,417(-9.1%)	$517,448	0.0%	+176.15%	0
JANE STREET GROUP, LLC	Decreased	304,459(-61.3%)	$444,510	0.0%	+175.16%	0
VFVANGUARD FIDUCIARY TRUST CO	New	300,897	$439,310	0.0%	+110.49%	33
UBS Group AG	Decreased	254,124(-35.3%)	$371,021	0.0%	+78.83%	0
STATE STREET CORP	Increased	248,837(+3.0%)	$363,302	0.0%	+7.39%	17
XTX Topco Ltd	Decreased	200,096(-30.8%)	$292,140	0.0%	+175.99%	0
Bank of New York Mellon Corp	Decreased	133,996(-18.8%)	$195,634	0.0%	-22.13%	0
NewEdge Wealth, LLC	Unchanged	116,006	$169,369	0.0%	-16.85%	0
NORTHERN TRUST CORP	Unchanged	101,948	$148,844	0.0%	-19.95%	0
TWO SIGMA INVESTMENTS, LP	Decreased	73,300(-30.5%)	$107,018	0.0%	+90.61%	0
MORGAN STANLEY	Decreased	69,688(-21.9%)	$101,744	0.0%	+51.91%	0
PANAGORA ASSET MANAGEMENT INC	New	69,424	$101,359	0.0%	+110.49%	30
CITADEL ADVISORS LLC	Decreased	61,249(-74.9%)	$89,424	0.0%	+36.82%	0
STIFEL FINANCIAL CORP	New	50,537	$73,784	0.0%	+110.49%	29

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Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer