RHYTHM PHARMACEUTICALS INC (RYTM) is held by 156 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is RA CAPITAL MANAGEMENT, L.P. as of Q1 2026.

Are institutions buying or selling RYTM?

In Q1 2026, 90 institutions opened or increased positions in RHYTHM PHARMACEUTICALS INC while 70 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on RYTM?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for RHYTHM PHARMACEUTICALS INC.

How many hedge funds hold RYTM?

156 institutional investors report holding RHYTHM PHARMACEUTICALS INC (RYTM) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into RYTM?

As of Q1 2026, tracked institutions in RHYTHM PHARMACEUTICALS INC show 90 buyers versus 70 sellers — net inflows.

RHYTHM PHARMACEUTICALS INC

RYTM·76243J105·US·Common Stock·Healthcare - Biotechnology-13D/G

156

Holders

(11 Elite)

$5.6B

Total Value

56% (160)

Consensus

90 buying - 70 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Held by 156 funds

11 elite

Who's Trading

ActivistPAPerceptive Advisors LLC5.1%May 15, 2026

ActivistVAVanguard Capital Management5.0%Apr 30, 2026

Activist

The Vanguard Group0.0%Mar 27, 2026

InsiderGPGerman Christopher PaulSell $503KMar 4, 2026

InsiderSCSmith Hunter CSell $131KFeb 19, 2026

InsiderSCSmith Hunter CSell $171KFeb 19, 2026

InsiderSCSmith Hunter CSell $82KFeb 19, 2026

InsiderSCSmith Hunter CSell $60KFeb 19, 2026

InsiderSCSmith Hunter CSell $119KFeb 17, 2026

InsiderSCSmith Hunter CSell $20KFeb 17, 2026

View all insider trades View all activist filings

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	6.7M	$579.8M	6.1%	+179.00%	0
BlackRock, Inc.	Decreased	6.2M(-1.0%)	$542.4M	0.0%	+91.57%	0
BAKER BROS. ADVISORS LP	Unchanged	5.6M	$487.4M	2.8%	+354.67%	0
PRIMECAP MANAGEMENT CO/CA/	Decreased	3.4M(-1.8%)	$297.2M	0.2%	+434.49%	0
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	3M	$264.5M	0.0%	+21.04%	43
VAVANGUARD CAPITAL MANAGEMENT LLC	New	3M	$258.1M	0.0%	+21.04%	43
STATE STREET CORP	Increased	2.3M(+3.3%)	$197.6M	0.0%	+97.92%	32
GOLDMAN SACHS GROUP INC	Increased	2M(+7.3%)	$170.9M	0.0%	+73.71%	33
WESTFIELD CAPITAL MANAGEMENT CO LP	Increased	1.9M(+52.2%)	$167.8M	0.7%	+48.81%	60
FMR LLC	Decreased	1.7M(-1.0%)	$147M	0.0%	+80.79%	0
PRICE T ROWE ASSOCIATES INC /MD/	Increased	1.7M(+6.0%)	$143.9M	0.0%	+85.95%	32
Polar Capital Holdings Plc	Increased	1.6M(+36.3%)	$140.5M	0.5%	+86.91%	47
CITADEL ADVISORS LLC	Increased	1.4M(+825.3%)	$123.4M	0.0%	+19.32%	49
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.4M(+3.0%)	$123.2M	0.0%	+253.85%	31
JPMORGAN CHASE & CO	Increased	1.6M(+9.1%)	$120M	0.0%	+33.94%	33
FEDERATED HERMES, INC.	Decreased	1.3M(-20.8%)	$111.9M	0.2%	+330.92%	0
ALLIANCEBERNSTEIN L.P.	Decreased	910,413(-2.1%)	$97.5M	0.0%	+13.35%	0
Capital Research Global Investors	Increased	1.1M(+13.2%)	$97M	0.0%	+6.83%	34
Janus Henderson Group Ltd.	Decreased	918,153(-18.5%)	$79.9M	0.0%	+133.28%	0
Point72 Asset Management, L.P.	Increased	846,801(+97.2%)	$73.6M	0.1%	+10.29%	48