SCILEX HOLDING CO (SCLX) is held by 34 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is VANGUARD CAPITAL MANAGEMENT LLC as of Q1 2026.

Are institutions buying or selling SCLX?

In Q1 2026, 10 institutions opened or increased positions in SCILEX HOLDING CO while 16 reduced or exited — a net selling quarter.

What is the Smart Money Verdict on SCLX?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for SCILEX HOLDING CO.

How many hedge funds hold SCLX?

34 institutional investors report holding SCILEX HOLDING CO (SCLX) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into SCLX?

As of Q1 2026, tracked institutions in SCILEX HOLDING CO show 10 buyers versus 16 sellers — net outflows.

SCILEX HOLDING CO

SCLX·80880W205·US·Common Stock·Healthcare - Drug Manufacturers - General-Activist

Holders

Avg rating(8 Elite)

$3.7M

Total Value

38% (39)

Fund Consensus

10 buying - 16 selling

Smart Money Verdict

View all

Held by 34 funds

8 elite

Who's Trading

ActivistSSSCLX Stock Acquisition JV LLC11.4%Jul 7, 2026

ActivistOPOramed Pharmaceuticals Inc.4.9%Feb 13, 2026

InsiderSCScilex Holding CoSell $5.2MDec 30, 2025

InsiderSCScilex Holding CoSell $4.8MDec 29, 2025

InsiderSCScilex Holding CoSell $2.8MDec 26, 2025

ActivistARArmistice Capital, LLC8.7%Aug 14, 2025

ActivistOPOramed Pharmaceuticals Inc.9.9%May 8, 2025

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
VAVANGUARD CAPITAL MANAGEMENT LLC	New	264,050	$1.8M	0.0%	+5.69%	39
BlackRock, Inc.	Increased	102,796(+4.5%)	$684,622	0.0%	-34.53%	17
VFVANGUARD FIDUCIARY TRUST CO	New	39,658	$264,122	0.0%	+5.69%	32
RENAISSANCE TECHNOLOGIES LLC	Decreased	36,864(-4.2%)	$245,514	0.0%	-51.22%	0
STATE STREET CORP	Increased	35,376(+3.0%)	$235,604	0.0%	-76.53%	16
XTX Topco Ltd	Increased	22,606(+10.6%)	$150,556	0.0%	-20.88%	25
NORTHERN TRUST CORP	Unchanged	15,033	$100,119	0.0%	-64.39%	0
MORGAN STANLEY	Decreased	11,973(-18.0%)	$79,741	0.0%	-70.78%	0
CITIGROUP INC	Decreased	8,954(-54.9%)	$59,634	0.0%	-22.93%	0
UBS Group AG	Decreased	6,468(-45.2%)	$43,077	0.0%	-34.21%	0
VGVanguard Global Advisers, LLC	New	2,937	$19,560	0.0%	+5.69%	29
ROYAL BANK OF CANADA	Increased	1,596(+80.5%)	$11,000	0.0%	-9.68%	18
MetLife Investment Management, LLC	Unchanged	1,090	$7,259	0.0%	-86.65%	0
$DEUTSCHE BANK AG\$ DEUTSCHE BANK AG\	Unchanged	800	$5,328	0.0%	-96.46%	0
JONES FINANCIAL COMPANIES LLLP	Decreased	752(-32.6%)	$4,820	0.0%	-63.66%	0
KLP KAPITALFORVALTNING AS	Unchanged	290	$1,931	0.0%	-35.64%	0
OSAIC HOLDINGS, INC.	Decreased	98(-91.5%)	$639	0.0%	-17.84%	0
WELLS FARGO & COMPANY/MN	Decreased	69(-43.0%)	$460	0.0%	+35.82%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Unchanged	44	$293	0.0%	-96.00%	0
RHUMBLINE ADVISERS	Unchanged	35	$232	0.0%	-96.45%	0