SEPTERNA INC

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SEPN·81734D104·US·Common Stock·Healthcare - Biotechnology-Activist

SEPN (SEPTERNA INC) is held by 96 institutional investors as of Q2 2026. Largest holders: RA CAPITAL MANAGEMENT, L.P. ($234.3M), DRIEHAUS CAPITAL MANAGEMENT LLC ($148.5M), GOLDMAN SACHS GROUP INC ($102.6M). Net institutional sentiment: Bullish.

96

Holders

(9 Elite)

$910M

Total Value

76% (94)

Consensus

71 buying - 23 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)64

Insider (Form 4)35

Activist (13D/13G)52

Congressional (STOCK Act)38

Holder Quality

25

★★★★★

Elite

69

★★★★

Strong

33

★★★

Solid

71

★★

Below

22

★

Weak

Held by 96 funds

9 elite

Who's Trading

Source dates: Price Oct 14, 2026 · Insiders Sep 3, 2026 · Activists Aug 14, 2026 · Congress none

InsiderLDLong Daniel D.Sell $126KSep 1, 2026

InsiderLDLong Daniel D.Exercise 3K shSep 1, 2026

ActivistRA Capital Management, L.P.11.8%Aug 14, 2026

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Top Holders

Top Holders (96)History

AllNewIncreasedHeldDecreasedExitedFirst report

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	7M	$234.3M	2.0%	+56.35%	0
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	4.4M(+0.8%)	$148.5M	0.9%	+110.70%	43
GOLDMAN SACHS GROUP INC	Increased	3.1M(+5.4%)	$102.6M	0.0%	+40.40%	32
BlackRock, Inc.	Increased	1.9M(+6.0%)	$64.7M	0.0%	+53.79%	31
Avoro Capital Advisors LLC	Unchanged	1.3M	$44.8M	0.4%	+80.21%	0
JTJupiter Topco LLC	First report	1.3M	$43.7M	0.0%	+8.45%	0
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	1.2M(+2.1%)	$40.9M	0.0%	+28.62%	30
PRIMECAP MANAGEMENT CO/CA/	Increased	1.2M(+11.3%)	$39.1M	0.0%	+27.39%	32
GEODE CAPITAL MANAGEMENT, LLC	Increased	679,163(+5.3%)	$22.8M	0.0%	+66.49%	30
STATE STREET CORP	Increased	652,630(+3.4%)	$21.9M	0.0%	+62.64%	29
LOOMIS SAYLES & CO L P	New	624,752	$20.9M	0.0%	+8.45%	39
BALYASNY ASSET MANAGEMENT L.P.	Increased	350,442(+48.1%)	$11.7M	0.0%	+21.61%	38
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	230,184(+18.0%)	$7.7M	0.0%	+25.47%	32
Universal- Beteiligungs- und Servicegesellschaft mbH	Decreased	222,702(-0.6%)	$7.5M	0.0%	+120.84%	0
TWO SIGMA INVESTMENTS, LP	Increased	220,885(+193.1%)	$7.4M	0.0%	+45.99%	44
NORTHERN TRUST CORP	Increased	201,131(+22.3%)	$6.7M	0.0%	+49.71%	33
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	187,041(+3.0%)	$6.3M	0.0%	+78.96%	28
Woodline Partners LP	New	185,535	$6.2M	0.0%	+8.45%	38
VFVANGUARD FIDUCIARY TRUST CO	Increased	165,656(+7.2%)	$5.5M	0.0%	+27.48%	29
MORGAN STANLEY	Increased	134,377(+21.6%)	$4.5M	0.0%	+56.42%	32

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer