SIONNA THERAPEUTICS INC (SION) is held by 76 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is RA CAPITAL MANAGEMENT, L.P. as of Q1 2026.

Are institutions buying or selling SION?

In Q1 2026, 45 institutions opened or increased positions in SIONNA THERAPEUTICS INC while 26 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on SION?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for SIONNA THERAPEUTICS INC.

How many hedge funds hold SION?

76 institutional investors report holding SIONNA THERAPEUTICS INC (SION) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into SION?

As of Q1 2026, tracked institutions in SIONNA THERAPEUTICS INC show 45 buyers versus 26 sellers — net inflows.

SIONNA THERAPEUTICS INC

SION·829401108·US·Common Stock·Healthcare - Biotechnology-Activist

Holders

(4 Elite)

$1B

Total Value

63% (71)

Consensus

45 buying - 26 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Held by 76 funds

4 elite

Who's Trading

InsiderFJFitzpatrick JenniferSell $447KJul 6, 2026

Activist

VIKING GLOBAL INVESTORS LP7.1%May 15, 2026

ActivistQIQatar Investment Authority4.5%May 12, 2026

InsiderTAThompson Peter A.Sell $8.5MMay 11, 2026

InsiderOLORBIMED ADVISORS LLCSell $8.5MMay 11, 2026

InsiderTAThompson Peter A.Sell $2.7MMay 8, 2026

InsiderOLORBIMED ADVISORS LLCSell $2.7MMay 8, 2026

InsiderOLORBIMED ADVISORS LLCSell $2.2MMay 7, 2026

InsiderTAThompson Peter A.Sell $2.2MMay 7, 2026

ActivistOAORBIMED ADVISORS LLC6.6%Apr 20, 2026

View all insider trades View all activist filings

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	9.9M	$397.1M	4.2%	+291.78%	0
VIKING GLOBAL INVESTORS LP	Unchanged	3.2M	$128.1M	0.4%	+281.08%	0
JENNISON ASSOCIATES LLC	Increased	1.5M(+30.1%)	$58.2M	0.0%	+103.77%	37
JPMORGAN CHASE & CO	Increased	1.5M(+18.9%)	$53.7M	0.0%	+197.38%	35
BlackRock, Inc.	Increased	1.3M(+0.3%)	$52M	0.0%	+72.54%	29
CITADEL ADVISORS LLC	Increased	1.2M(+7.3%)	$46.8M	0.0%	+13.30%	31
VAVANGUARD CAPITAL MANAGEMENT LLC	New	1M	$41.3M	0.0%	+32.85%	40
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	756,376(-9.0%)	$30.3M	0.0%	+144.72%	0
STATE STREET CORP	Increased	756,227(+9.1%)	$30.3M	0.0%	+30.60%	31
Aberdeen Group plc	Decreased	564,175(-32.8%)	$22.6M	0.0%	+262.87%	0
BAKER BROS. ADVISORS LP	Unchanged	400,000	$16M	0.1%	+291.78%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	389,872(+2.6%)	$15.6M	0.0%	+127.25%	29
GOLDMAN SACHS GROUP INC	Increased	263,174(+625.6%)	$10.6M	0.0%	+34.33%	45
Ensign Peak Advisors, Inc	Increased	255,636(+220.1%)	$10.2M	0.0%	+24.52%	45
Candriam S.C.A.	New	236,813	$9.5M	0.0%	+32.85%	38
FRANKLIN RESOURCES INC	Unchanged	175,483	$7M	0.0%	+291.78%	0
AGADAGE CAPITAL PARTNERS GP, L.L.C.	New	150,000	$6M	0.0%	+32.85%	38
UBS Group AG	Increased	147,641(+65.6%)	$5.9M	0.0%	+50.32%	40
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	142,081	$5.7M	0.0%	+32.85%	37
MILLENNIUM MANAGEMENT LLC	Increased	140,641(+74.6%)	$5.6M	0.0%	+47.05%	41