SKYE BIOSCIENCE INC (SKYE) is held by 27 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is BAKER BROS. ADVISORS LP as of Q1 2026.

Are institutions buying or selling SKYE?

In Q1 2026, 11 institutions opened or increased positions in SKYE BIOSCIENCE INC while 15 reduced or exited — a net selling quarter.

What is the Smart Money Verdict on SKYE?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for SKYE BIOSCIENCE INC.

How many hedge funds hold SKYE?

27 institutional investors report holding SKYE BIOSCIENCE INC (SKYE) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into SKYE?

As of Q1 2026, tracked institutions in SKYE BIOSCIENCE INC show 11 buyers versus 15 sellers — net outflows.

SKYE BIOSCIENCE INC

SKYE·83086J200·US·Common Stock·Healthcare - Biotechnology-Activist

Holders

Avg rating(7 Elite)

$2.2M

Total Value

42% (35)

Fund Consensus

11 buying - 15 selling

Smart Money Verdict

View all

Held by 27 funds

7 elite

Who's Trading

Activist5V5AM Partners VII, LLC29.2%Dec 16, 2025

Insider5L5AM Partners VII, LLCSell $561KAug 22, 2025

InsiderSJSchwab Andrew J.Sell $561KAug 22, 2025

InsiderSJSchwab Andrew J.Sell $22KAug 22, 2025

Insider5L5AM Partners VII, LLCSell $22KAug 22, 2025

InsiderSJSchwab Andrew J.Sell $209KAug 21, 2025

Insider5L5AM Partners VII, LLCSell $209KAug 21, 2025

Insider5L5AM Partners VII, LLCSell $8KAug 21, 2025

InsiderSJSchwab Andrew J.Sell $8KAug 21, 2025

Activist

Schonfeld Strategic Advisors LLC3.6%Aug 14, 2025

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BAKER BROS. ADVISORS LP	Increased	1.6M(+8.6%)	$968,144	0.0%	-85.78%	27
VAVANGUARD CAPITAL MANAGEMENT LLC	New	764,457	$470,141	0.0%	-6.76%	37
BlackRock, Inc.	Increased	286,131(+1.5%)	$175,855	0.0%	-72.51%	16
GEODE CAPITAL MANAGEMENT, LLC	Increased	277,256(+31.9%)	$170,447	0.0%	-87.37%	20
MILLENNIUM MANAGEMENT LLC	Decreased	258,200(-32.1%)	$158,690	0.0%	-83.21%	0
VFVANGUARD FIDUCIARY TRUST CO	New	104,229	$64,101	0.0%	-6.76%	32
STATE STREET CORP	Unchanged	75,326	$46,295	0.0%	-90.20%	0
UBS Group AG	Increased	45,762(+244.4%)	$28,143	0.0%	-44.72%	21
XTX Topco Ltd	Decreased	40,919(-22.9%)	$25,149	0.0%	-5.48%	0
TWO SIGMA INVESTMENTS, LP	Decreased	25,684(-50.3%)	$15,785	0.0%	-81.01%	0
EGEngineers Gate Manager LP	Decreased	20,194(-12.7%)	$12,411	0.0%	-5.48%	0
NORTHERN TRUST CORP	Unchanged	20,142	$12,379	0.0%	-86.18%	0
BARCLAYS PLC	Decreased	18,089(-14.9%)	$11,117	0.0%	-5.48%	0
GROUP ONE TRADING LLC	Decreased	7,205(-59.3%)	$4,428	0.0%	-40.47%	0
VGVanguard Global Advisers, LLC	New	4,557	$2,803	0.0%	-6.76%	20
MORGAN STANLEY	Decreased	2,549(-40.3%)	$1,567	0.0%	-86.67%	0
FEDERATED HERMES, INC.	Unchanged	1,158	$712	0.0%	-5.48%	0
OSAIC HOLDINGS, INC.	Increased	600(+299x)	$364	0.0%	-8.13%	12
NATIONAL BANK OF CANADA /FI/	Unchanged	400	$242	0.0%	-5.48%	0
TD Waterhouse Canada Inc.	Increased	79(+216.0%)	$51	0.0%	-52.45%	12