SPRUCE BIOSCIENCES INC

SPRB (SPRUCE BIOSCIENCES INC) is held by 15 institutional investors as of Q1 2026. Largest holders: MILLENNIUM MANAGEMENT LLC ($7.3M), CITADEL ADVISORS LLC ($4.6M), Alyeska Investment Group, L.P. ($3.4M). Net institutional sentiment: Mixed.

15

Holders

$28.1M

Total Value

40% (15)

Consensus

6 buying - 9 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

SPSmart Money Verdict

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Institutional (13F)

Insider (Form 4)

Activist (13D/13G)

Congressional (STOCK Act)

Holder Quality

★★★★★

Elite

★★★★

Strong

★★★

Solid

★★

Below

★

Weak

Held by 15 funds

Who's Trading

ActivistAIAlyeska Investment Group, L.P.4.5%May 15, 2026

ActivistWellington Management Group LLP3.6%May 15, 2026

ActivistKenneth Griffin5.1%May 15, 2026

ActivistSMSquadron Master Fund LP0.9%May 15, 2026

ActivistIKIkarian Capital, LLC4.8%May 7, 2026

ActivistExodusPoint Capital Management, LP0.8%Apr 28, 2026

ActivistICIntegrated Core Strategies (US) LLC9.6%Feb 24, 2026

InsiderPLParkman Healthcare Partners LLCBuy $5KOct 6, 2025

InsiderPLParkman Healthcare Partners LLCSell $4KOct 6, 2025

InsiderPLParkman Healthcare Partners LLCSell $436.393Oct 6, 2025

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Top Holders (15)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
MILLENNIUM MANAGEMENT LLC	New	111,888	$7.3M	0.0%	-10.32%	38
CITADEL ADVISORS LLC	Unchanged	69,999	$4.6M	0.0%	-39.43%	0
AIAlyeska Investment Group, L.P.	Unchanged	51,671	$3.4M	0.0%	-39.43%	0
WELLINGTON MANAGEMENT GROUP LLP	Decreased	48,796(-17.2%)	$3.2M	0.0%	-39.43%	0
BALYASNY ASSET MANAGEMENT L.P.	Unchanged	40,000	$2.6M	0.0%	-39.43%	0
Carlyle Group Inc.	Unchanged	38,620	$2.5M	0.0%	+416.19%	0
ExodusPoint Capital Management, LP	Decreased	22,000(-12.9%)	$1.4M	0.0%	-39.43%	0
BlackRock, Inc.	Unchanged	16,938	$1.1M	0.0%	-39.43%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	12,889(+1.2%)	$842,729	0.0%	-39.19%	25
GOLDMAN SACHS GROUP INC	New	5,506	$359,817	0.0%	-10.32%	36
STATE STREET CORP	Decreased	5,400(-15.6%)	$352,890	0.0%	-39.43%	0
UBS Group AG	Decreased	3,919(-20.1%)	$256,107	0.0%	-37.96%	0
MORGAN STANLEY	Increased	1,415(+264.7%)	$92,471	0.0%	-13.87%	24
CITIGROUP INC	New	939	$61,364	0.0%	-10.32%	32
JONES FINANCIAL COMPANIES LLLP	Increased	193(+129.8%)	$12,167	0.0%	-25.84%	19
NORTHERN TRUST CORP	Exited	0(-100.0%)	$210,980	0.0%	-32.47%	0
ROYAL BANK OF CANADA	Exited	0(-100.0%)	$3,000	0.0%	-32.47%	0
Schonfeld Strategic Advisors LLC	Exited	0(-100.0%)	$2.2M	0.0%	-32.47%	0
BANK OF AMERICA CORP /DE/	Exited	0(-100.0%)	$8,101	0.0%	-30.49%	0
BNP PARIBAS FINANCIAL MARKETS	Exited	0(-100.0%)	$174,220	0.0%	-32.47%	0

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