TAYSHA GENE THERAPIES INC (TSHA) is held by 117 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is RA CAPITAL MANAGEMENT, L.P. as of Q1 2026.

Are institutions buying or selling TSHA?

In Q1 2026, 60 institutions opened or increased positions in TAYSHA GENE THERAPIES INC while 50 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on TSHA?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for TAYSHA GENE THERAPIES INC.

How many hedge funds hold TSHA?

117 institutional investors report holding TAYSHA GENE THERAPIES INC (TSHA) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into TSHA?

As of Q1 2026, tracked institutions in TAYSHA GENE THERAPIES INC show 60 buyers versus 50 sellers — net inflows.

TAYSHA GENE THERAPIES INC

TSHA·877619106·US·Common Stock·Healthcare - Biotechnology-Activist

117

Holders

Avg rating(26 Elite)

$920.1M

Total Value

55% (130)

Fund Consensus

60 buying - 50 selling

Smart Money Verdict

View all

Held by 117 funds

26 elite

Who's Trading

InsiderNSNagendran SukumarSell $1.2MJul 10, 2026

Activist

RTW Investments, LP7.0%May 15, 2026

ActivistVPVestal Point Capital, LP6.3%May 15, 2026

InsiderNSNagendran SukumarSell $892KApr 10, 2026

Activist

FMR LLC4.9%Feb 5, 2026

InsiderNPNolan Sean P.Sell $190KJan 26, 2026

InsiderAKAlam KamranSell $110KJan 26, 2026

InsiderNSNagendran SukumarSell $124KJan 26, 2026

InsiderNPNolan Sean P.Sell $650KJan 23, 2026

InsiderAKAlam KamranSell $375KJan 23, 2026

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	23.6M	$105.3M	1.1%	+131.39%	0
GOLDMAN SACHS GROUP INC	Increased	22.4M(+63.4%)	$100M	0.0%	+93.49%	44
Avoro Capital Advisors LLC	Unchanged	21.7M	$97M	1.0%	+127.13%	0
BlackRock, Inc.	Decreased	18.4M(-1.5%)	$82.1M	0.0%	+159.23%	0
MORGAN STANLEY	Decreased	18M(-0.6%)	$80.3M	0.0%	+201.43%	0
FMR LLC	Increased	14.3M(+5.9%)	$64M	0.0%	+236.34%	31
RTW INVESTMENTS, LP	Decreased	13.7M(-16.6%)	$61.2M	0.6%	+158.16%	0
STATE STREET CORP	Increased	11.2M(+3.9%)	$50.1M	0.0%	+79.15%	30
VAVANGUARD CAPITAL MANAGEMENT LLC	New	10.2M	$45.7M	0.0%	+39.96%	40
Polar Capital Holdings Plc	Decreased	5.7M(-28.7%)	$25.3M	0.1%	+69.68%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	5.5M(+2.7%)	$24.7M	0.0%	+85.21%	29
DED. E. Shaw & Co., Inc.	Increased	4.4M(+10.3%)	$19.8M	0.0%	+60.29%	31
BAKER BROS. ADVISORS LP	Unchanged	4M	$17.9M	0.1%	+140.21%	0
MILLENNIUM MANAGEMENT LLC	Increased	3.3M(+3.2%)	$14.7M	0.0%	+158.47%	29
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	Decreased	2.9M(-22.5%)	$12.9M	0.0%	+12.01%	0
BARCLAYS PLC	Decreased	2.8M(-49.2%)	$11.4M	0.0%	+95.72%	0
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	2M	$9M	0.0%	+39.96%	38
NORTHERN TRUST CORP	Increased	1.8M(+46.5%)	$8.1M	0.0%	+92.95%	37
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	1.8M(-5.0%)	$8.1M	0.0%	+101.75%	0
BANK OF AMERICA CORP /DE/	Increased	1.7M(+45.5%)	$7.5M	0.0%	+106.44%	37