ZYMEWORKS INC (ZYME) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling ZYME?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for ZYMEWORKS INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on ZYME?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for ZYMEWORKS INC.

Is institutional money flowing into ZYME?

120 institutional investors hold ZYMEWORKS INC (ZYME). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about ZYME?

Track institutional sentiment and conviction scores for ZYMEWORKS INC (ZYME) including Smart Money Verdict and position changes on HoldingsIntel.

ZYMEWORKS INC

ZYME·98985Y108·US·equity·Healthcare - Biotechnology-Activist

120

Holders

Avg rating(13 Elite)

$608.8M

Total Value

53% (132)

Fund Consensus

65 buying - 57 selling

Smart Money Verdict

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43Weak MomentumSplit Signals

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See how ZYME's score breaks down across 4 SEC sources

Held by 120 funds

13 elite

Who's Trading

ActivistRURubric Capital Management LP9.5%May 15, 2026

ActivistPAPerceptive Advisors LLC5.4%Apr 15, 2026

InsiderHMHollywood MarkSell $139KJan 12, 2026

InsiderGKGalbraith KennethSell $690KJan 12, 2026

InsiderMAMoore Paul AndrewSell $217KJan 12, 2026

InsiderSLSmith Jeffrey T LSell $211KJan 12, 2026

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Decreased	4.6M(-0.9%)	$114M	0.0%	+47.61%	0
MORGAN STANLEY	Decreased	2.5M(-4.3%)	$62.1M	0.0%	+158.53%	0
BNP Paribas Asset Management Holding S.A.	Increased	1.9M(+4.7%)	$47.8M	0.1%	-9.51%	31
CITADEL ADVISORS LLC	Increased	1.2M(+350.4%)	$28.8M	0.0%	+6.83%	46
DIMENSIONAL FUND ADVISORS LP	Decreased	1.1M(-1.7%)	$28.5M	0.0%	+142.17%	0
STATE STREET CORP	Decreased	1M(-2.5%)	$25.3M	0.0%	+129.47%	0
$DEUTSCHE BANK AG\$ DEUTSCHE BANK AG\	Decreased	921,250(-42.3%)	$23.1M	0.0%	+146.03%	0
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	Increased	743,898(+6.3%)	$18.6M	0.0%	+6.40%	30
Assenagon Asset Management S.A.	Increased	727,986(+12.4%)	$18.2M	0.0%	+42.65%	32
FMR LLC	Increased	667,153(+19.1%)	$16.7M	0.0%	-8.46%	33
GEODE CAPITAL MANAGEMENT, LLC	Increased	659,940(+1.9%)	$16.5M	0.0%	+166.16%	29
Nuveen, LLC	Increased	651,662(+0.5%)	$16.3M	0.0%	+67.39%	28
GOLDMAN SACHS GROUP INC	Increased	599,486(+42.7%)	$15M	0.0%	+42.37%	38
Qube Research & Technologies Ltd	Increased	511,937(+7.9%)	$12.8M	0.0%	+13.42%	30
NORTHERN TRUST CORP	Increased	320,210(+4.0%)	$8M	0.0%	+150.55%	29
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Decreased	319,385(-0.3%)	$8M	0.0%	+117.37%	0
ROYCE & ASSOCIATES LP	New	299,202	$7.5M	0.1%	-2.13%	38
PICTON MAHONEY ASSET MANAGEMENT	Increased	256,690(+4.9%)	$6.4M	0.0%	+106.45%	29
BANK OF AMERICA CORP /DE/	Increased	236,754(+164.5%)	$5.9M	0.0%	+14.06%	44
DED. E. Shaw & Co., Inc.	Increased	235,621(+5.3%)	$5.9M	0.0%	+27.78%	29

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High Conviction Moves-Signal Convergence-Fund Consensus-Double-Down Signals

Data sourced from four SEC data sources: 13F, Form 4, 13D/13G, and STOCK Act. Not financial advice. Full disclaimer