Question 1

How many shares of KPTI does RENAISSANCE TECHNOLOGIES LLC own?

Accepted Answer

As of 2026-Q1, RENAISSANCE TECHNOLOGIES LLC holds 105,414 shares of KPTI (KARYOPHARM THERAPEUTICS INC).

Question 2

What is RENAISSANCE TECHNOLOGIES LLC's KPTI position worth?

Accepted Answer

As of 2026-Q1, RENAISSANCE TECHNOLOGIES LLC's KPTI position is worth $587,156.

Question 3

Is RENAISSANCE TECHNOLOGIES LLC buying or selling KPTI?

Accepted Answer

In 2026-Q1, RENAISSANCE TECHNOLOGIES LLC increased their KPTI position (+75.9% change in shares).

Question 4

When did RENAISSANCE TECHNOLOGIES LLC first buy KPTI?

Accepted Answer

Based on available 13F filings, RENAISSANCE TECHNOLOGIES LLC first reported a position in KPTI in 2019-Q4. They have held the position across 24 quarters.

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2026-Q1 Latest	Increased	105,414	+75.9%	$587,156	0.0%	$9.13	37
2025-Q4	Decreased	59,914	-7.4%	$440,967	0.0%	$7.31	0
2025-Q3	Decreased	64,714	-1.7%	$423,230	0.0%	$6.35	0
2025-Q2	Increased	65,814	+7.5%	$283,658	0.0%	$4.39	25
2025-Q1	Decreased	61,214	-94.9%	$228,940	0.0%	$4.16	0
2024-Q4	Decreased	1.2M	-3.1%	$813,312	0.0%	$10.50	0
2024-Q3	Increased	1.2M	+64.2%	$1M	0.0%	$10.86	37
2024-Q2	Decreased	756,227	-16.6%	$656,103	0.0%	$13.02	0
2024-Q1	Decreased	906,800	-53.8%	$1.4M	0.0%	$22.65	0
2023-Q4	Increased	2M	+168.9%	$1.7M	0.0%	$12.98	41
2023-Q3	Increased	730,400	+9.4%	$979,000	0.0%	$20.10	27
2023-Q2	Decreased	667,400	-9.3%	$1.2M	0.0%	$27.45	0
2023-Q1	Increased	735,700	+288.6%	$2.9M	0.0%	$52.80	42
2022-Q4	Decreased	189,300	-38.6%	$644,000	0.0%	$51.00	0
2022-Q3	Decreased	308,300	-32.2%	$1.7M	0.0%	$80.55	0
2022-Q2	Increased	454,800	+111.4%	$2.1M	0.0%	$67.65	42
2022-Q1	Increased	215,100	+150.4%	$1.6M	0.0%	$110.25	41
2021-Q4	Decreased	85,900	-82.7%	$552,000	0.0%	$100.80	0
2021-Q3	Increased	495,400	+2581.9%	$2.9M	0.0%	$88.35	42
2021-Q2	New	18,472	-	$191,000	0.0%	$154.05	31
2020-Q3	Exited	0	-100.0%	$0	0.0%	$218.85	0
2020-Q2	Decreased	181,800	-66.0%	$3.4M	0.0%	$270.00	0
2020-Q1	Increased	534,000	+232.7%	$10.3M	0.0%	$300.30	45
2019-Q4	New	160,500	-	$3.1M	0.0%	$284.10	37

KPTI24 quarters

KPTI
24 quarters