Question 1

Does Two Sigma Investments own PRQR stock?

Accepted Answer

Yes. As of its Q2 2026 13F, Two Sigma Investments holds 1,138,715 shares of PRQR (ProQR Therapeutics), worth $2.1M.

Question 2

How many shares of PRQR does Two Sigma Investments own?

Accepted Answer

As of its Q2 2026 13F, Two Sigma Investments holds 1,138,715 shares of PRQR (ProQR Therapeutics).

Question 3

What is Two Sigma Investments' PRQR position worth?

Accepted Answer

As of its Q2 2026 13F, Two Sigma Investments' PRQR position is worth $2.1M.

Question 4

Is Two Sigma Investments buying or selling PRQR?

Accepted Answer

In Q2 2026, Two Sigma Investments increased its PRQR position by 219,858 shares (+23.9%).

Question 5

When did Two Sigma Investments first buy PRQR?

Accepted Answer

Two Sigma Investments already held PRQR in its Q4 2018 13F, the earliest on record, and has listed it in 29 quarterly 13F filings.

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2026-Q2 Latest	Increased	1.1M	+23.9%	$2.1M	0.0%	$1.86	32
2026-Q1	Increased	918,857	+9.5%	$1.5M	0.0%	$1.62	28
2025-Q4	Increased	839,384	+101.2%	$1.7M	0.0%	$2.02	41
2025-Q3	Increased	417,300	+86.3%	$888,849	0.0%	$2.13	39
2025-Q2	Decreased	224,040	-25.8%	$457,042	0.0%	$2.04	0
2025-Q1	Decreased	301,912	-21.2%	$401,543	0.0%	$1.33	0
2024-Q4	Increased	383,134	+512.8%	$1M	0.0%	$2.65	40
2024-Q3	Decreased	62,520	-9.3%	$113,786	0.0%	$1.83	0