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Position history for TWO SIGMA INVESTMENTS, LPTWO SIGMA INVESTMENTS, LP's holdings in ALNYLAM PHARMACEUTICALS INC

Yes. Two Sigma holds 1,875,937 shares of ALNY (Alnylam Pharmaceuticals), worth $564.7M, as of its Q2 2026 13F filing. It reduced the position by 116,640 shares (-5.9%) from Q1 2026. Two Sigma has held ALNY since Q1 2024, across 10 quarterly 13F filings. ALNY is 0.4% of Two Sigma's reported 13F portfolio.

Current Value

$564.7M

Current Shares

1.9M

Total Value Change

+$559.4M

Total Shares Change

+1.9M

Quarter-by-Quarter History
QuarterActionSharesChangeValueWeightPriceConviction
2026-Q2
Latest
Decreased
1.9M
-5.8%
$564.7M0.4%$301.03
0
2026-Q1
Increased
2M
+223.4%
$659.3M0.5%$330.87
72
2025-Q4
Increased
616,120
+3.4%
$245M0.3%$397.65
38
2025-Q3
Increased
595,926
+73.6%
$271.7M0.4%$456.00
55
2025-Q2
Increased
343,305
+73.9%
$111.9M0.2%$326.09
54
2025-Q1
Increased
197,415
+84.3%
$53.3M0.1%$270.02
54
2024-Q4
Increased
107,117
+459.4%
$25.2M0.1%$235.31
46
2024-Q3
Decreased
19,148
-81.4%
$5.3M0.0%$275.03
0

Other major holders of ALNY: FMR LLC, Capital World Investors, VANGUARD GROUP INC

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