How many shares of VRTX does TWO SIGMA INVESTMENTS, LP own?

As of 2026-Q2, TWO SIGMA INVESTMENTS, LP holds 285,000 shares of VRTX (VERTEX PHARMACEUTICALS INC).

What is TWO SIGMA INVESTMENTS, LP's VRTX position worth?

As of 2026-Q2, TWO SIGMA INVESTMENTS, LP's VRTX position is worth $141.6M.

Is TWO SIGMA INVESTMENTS, LP buying or selling VRTX?

In 2026-Q2, TWO SIGMA INVESTMENTS, LP decreased their VRTX position (-24.6% change in shares).

When did TWO SIGMA INVESTMENTS, LP first buy VRTX?

Based on available 13F filings, TWO SIGMA INVESTMENTS, LP first reported a position in VRTX in 2018-Q4. They have held the position across 26 quarters.

Back to

TWO SIGMA INVESTMENTS, LP

VRTX
26 quarters

Position history for TWO SIGMA INVESTMENTS, LP's holdings in VERTEX PHARMACEUTICALS INC

Current Value

$141.6M

Current Shares

285,000

Total Value Change

+$74.1M

Total Shares Change

-122,069

Quarter-by-Quarter History

Quarter	Action	Shares	Change	Value	Weight	Price	Conviction
2026-Q2 Latest	Decreased	285,000	-24.6%	$141.6M	0.1%	$496.73	0
2026-Q1	Increased	378,146	+9001.0%	$168.9M	0.1%	$474.27	59
2025-Q4	New	4,155	-	$1.9M	0.0%	$453.74	36
2025-Q2	Exited	0	-100.0%	$0	0.0%	$441.30	0
2025-Q1	Decreased	4,121	-87.6%	$2M	0.0%	$492.69	0
2024-Q4	Decreased	33,160	-79.3%	$13.4M	0.0%	$399.35	0
2024-Q3	Decreased	160,535	-51.6%	$74.7M	0.2%	$462.88	0
2024-Q2	Increased	331,987	+2.3%	$155.6M	0.4%	$468.72	37
2024-Q1	Increased	324,428	+138.3%	$135.6M	0.3%	$418.01	58
2023-Q4	Decreased	136,174	-47.5%	$55.4M	0.1%	$406.89	0
2023-Q3	Decreased	259,429	-33.3%	$90.2M	0.2%	$347.74	0
2023-Q2	Increased	388,883	+326.1%	$136.9M	0.3%	$348.18	58
2023-Q1	Increased	91,255	+213.3%	$28.8M	0.1%	$312.16	46
2022-Q4	New	29,122	-	$8.4M	0.0%	$288.78	38
2022-Q2	Exited	0	-100.0%	$0	0.0%	$280.35	0
2022-Q1	New	33,644	-	$8.8M	0.0%	$256.52	38
2021-Q4	Exited	0	-100.0%	$0	0.0%	$222.45	0
2021-Q3	New	959,684	-	$174.1M	0.4%	$182.22	50
2020-Q3	Exited	0	-100.0%	$0	0.0%	$270.31	0
2020-Q2	Decreased	102,102	-78.0%	$29.6M	0.1%	$285.18	0
2020-Q1	Decreased	465,146	-41.4%	$110.7M	0.9%	$231.92	0
2019-Q4	Increased	793,469	+54.8%	$173.7M	0.5%	$218.97	60
2019-Q3	Increased	512,635	+22.9%	$86.9M	0.3%	$166.74	43
2019-Q2	Decreased	417,171	-36.8%	$76.5M	0.3%	$183.38	0
2019-Q1	Increased	660,524	+62.3%	$121.5M	0.4%	$183.95	52
2018-Q4	New	407,069	-	$67.5M	0.3%	$161.42	49

Other major holders of VRTX: BNP PARIBAS FINANCIAL MARKETS, Capital World Investors

VRTX26 quarters

VRTX
26 quarters