ARDELYX INC (ARDX) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling ARDX?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for ARDELYX INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on ARDX?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for ARDELYX INC.

Is institutional money flowing into ARDX?

133 institutional investors hold ARDELYX INC (ARDX). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about ARDX?

Track institutional sentiment and conviction scores for ARDELYX INC (ARDX) including Smart Money Verdict and position changes on HoldingsIntel.

ARDELYX INC

ARDX·039697107·US·equity·Healthcare - Biotechnology-13D/G

ARDX (ARDELYX INC) is held by 133 institutional investors as of Q4 2025. Largest holders: BlackRock, Inc. ($123.2M), VANGUARD GROUP INC ($110.7M), JANUS HENDERSON GROUP PLC ($84.6M). Net institutional sentiment: Mixed.

133

Holders

Avg rating(10 Elite)

$886.3M

Total Value

51% (146)

Fund Consensus

66 buying - 61 selling

Smart Money Verdict- Q4 2025View all

47Weak MomentumStrong Convergence

Held by 133 funds

10 elite

Who's Trading

ActivistThe Vanguard Group0.0%Mar 26, 2026

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

InsiderRAAB MICHAELSell $237KFeb 20, 2026

InsiderReilly Joseph JamesSell $26KFeb 20, 2026

ActivistThe Vanguard Group7.8%Jan 30, 2026

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	21.1M(+1.5%)	$123.2M	0.0%	+23.10%	31
VANGUARD GROUP INC	Increased	19M(+3.3%)	$110.7M	0.0%	-0.03%	31
JANUS HENDERSON GROUP PLC	Increased	14.5M(+5.0%)	$84.6M	0.0%	+64.66%	31
STATE STREET CORP	Increased	11.9M(+22.6%)	$69.4M	0.0%	+1.44%	36
MILLENNIUM MANAGEMENT LLC	Increased	11.9M(+55.8%)	$69.4M	0.0%	+18.24%	42
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	New	9.3M	$54.4M	0.1%	+7.24%	41
GEODE CAPITAL MANAGEMENT, LLC	Increased	5.8M(+1.2%)	$34M	0.0%	+58.58%	29
MARSHALL WACE, LLP	Decreased	5.2M(-42.0%)	$30.2M	0.0%	+34.71%	0
Nuveen, LLC	Decreased	5.2M(-0.2%)	$30.1M	0.0%	+21.05%	0
GOLDMAN SACHS GROUP INC	Increased	3.1M(+18.6%)	$17.9M	0.0%	+29.93%	33
TWO SIGMA INVESTMENTS, LP	Increased	2.9M(+15.4%)	$16.8M	0.0%	+18.61%	32
MORGAN STANLEY	Decreased	2.4M(-18.3%)	$13.8M	0.0%	-5.32%	0
BANK OF AMERICA CORP /DE/	Decreased	2.2M(-16.8%)	$12.9M	0.0%	+31.05%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	2.1M(-3.5%)	$12.3M	0.0%	+47.04%	0
JANE STREET GROUP, LLC	Decreased	2.1M(-6.1%)	$12M	0.0%	+14.84%	0
AQR CAPITAL MANAGEMENT LLC	Decreased	2M(-5.5%)	$11.8M	0.0%	+25.71%	0
NORTHERN TRUST CORP	Decreased	2M(-4.7%)	$11.8M	0.0%	+64.47%	0
JONES FINANCIAL COMPANIES LLLP	Decreased	1.9M(-1.0%)	$10.8M	0.0%	+7.35%	0
RENAISSANCE TECHNOLOGIES LLC	Increased	1.8M(+6.2%)	$10.5M	0.0%	+21.19%	30
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	Increased	1.4M(+146.1%)	$8.3M	0.0%	+8.53%	44
D. E. Shaw & Co., Inc.	Decreased	1.4M(-57.4%)	$8.2M	0.0%	+22.96%	0
TWO SIGMA ADVISERS, LP	Decreased	1.3M(-16.5%)	$7.9M	0.0%	+25.29%	0
CITADEL ADVISORS LLC	Decreased	1.3M(-13.2%)	$7.7M	0.0%	+1.82%	0
Qube Research & Technologies Ltd	New	1.1M	$6.4M	0.0%	+7.24%	38
FIRST TRUST ADVISORS LP	Increased	1M(+467.6%)	$6M	0.0%	+14.58%	44
BNP PARIBAS FINANCIAL MARKETS	Increased	1M(+15.7%)	$5.8M	0.0%	+10.10%	31
Point72 Asset Management, L.P.	New	958,690	$5.6M	0.0%	+7.24%	37
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	776,205(+25.2%)	$4.5M	0.0%	+22.45%	33
BARCLAYS PLC	Increased	763,364(+4.8%)	$4.5M	0.0%	+44.70%	28
JPMORGAN CHASE & CO	Decreased	736,190(-26.6%)	$4.3M	0.0%	+12.47%	0
Bank of New York Mellon Corp	Decreased	723,158(-2.2%)	$4.2M	0.0%	+72.36%	0
Freestone Grove Partners LP	Increased	699,133(+74.0%)	$4.1M	0.0%	+17.33%	40
FMR LLC	Increased	677,436(+3066.9%)	$3.9M	0.0%	+7.81%	43
PANAGORA ASSET MANAGEMENT INC	Decreased	659,160(-0.1%)	$3.8M	0.0%	+2.72%	0
UBS Group AG	Increased	578,344(+25.4%)	$3.4M	0.0%	+10.31%	33
DEUTSCHE BANK AG\	Increased	500,195(+157.8%)	$2.9M	0.0%	+7.54%	42
Swiss National Bank	Increased	475,200(+2.4%)	$2.8M	0.0%	+35.98%	27
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	431,247(+16.5%)	$2.5M	0.0%	+19.62%	30
Rafferty Asset Management, LLC	Increased	390,214(+24.0%)	$2.3M	0.0%	+27.55%	32
PRUDENTIAL FINANCIAL INC	Decreased	388,840(-13.4%)	$2.3M	0.0%	+26.67%	0
SCHRODER INVESTMENT MANAGEMENT GROUP	New	368,448	$2.1M	0.0%	+7.24%	36
Universal- Beteiligungs- und Servicegesellschaft mbH	Increased	347,609(+0.7%)	$2M	0.0%	+24.85%	26
Squarepoint Ops LLC	Decreased	346,142(-12.8%)	$2M	0.0%	+31.04%	0
Trexquant Investment LP	Decreased	327,159(-35.1%)	$1.9M	0.0%	+16.59%	0
WELLS FARGO & COMPANY/MN	Increased	318,413(+58.2%)	$1.9M	0.0%	-1.70%	37
Invesco Ltd.	Increased	317,410(+23.1%)	$1.9M	0.0%	+24.59%	31
RHUMBLINE ADVISERS	Decreased	297,924(-12.6%)	$1.7M	0.0%	+65.98%	0
CAPITAL FUND MANAGEMENT S.A.	Decreased	283,892(-42.7%)	$1.7M	0.0%	+44.65%	0
Legal & General Group Plc	Decreased	268,263(-0.3%)	$1.6M	0.0%	+42.62%	0
ALLIANCEBERNSTEIN L.P.	Unchanged	267,340	$1.6M	0.0%	+53.96%	0
IEQ CAPITAL, LLC	Decreased	246,434(-3.1%)	$1.4M	0.0%	+22.19%	0
Walleye Capital LLC	Decreased	221,308(-81.7%)	$1.3M	0.0%	+10.63%	0
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Increased	217,662(+0.0%)	$1.3M	0.0%	+52.83%	25
MACKENZIE FINANCIAL CORP	Increased	199,550(+12.8%)	$1.2M	0.0%	+32.49%	28
STATE OF WISCONSIN INVESTMENT BOARD	Decreased	195,944(-20.1%)	$1.1M	0.0%	+50.84%	0
RAYMOND JAMES FINANCIAL INC	Increased	193,769(+115.3%)	$1.1M	0.0%	+12.95%	41
LPL Financial LLC	Decreased	159,932(-1.3%)	$932,404	0.0%	+22.85%	0
FRANKLIN RESOURCES INC	Decreased	154,698(-79.5%)	$901,889	0.0%	+18.49%	0
GROUP ONE TRADING LLC	Increased	153,811(+64.9%)	$896,718	0.0%	-7.71%	36
SIMPLEX TRADING, LLC	Decreased	151,934(-27.4%)	$885,775	0.0%	+10.14%	0
Engineers Gate Manager LP	Decreased	137,582(-42.8%)	$802,103	0.0%	+15.08%	0
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	134,029(+6.6%)	$780,707	0.0%	-13.09%	26
CANADA PENSION PLAN INVESTMENT BOARD	New	131,900	$768,977	0.0%	+7.24%	34
INTECH INVESTMENT MANAGEMENT LLC	Increased	124,381(+9.8%)	$725,141	0.0%	+12.89%	27
Man Group plc	Decreased	124,211(-36.3%)	$724,150	0.0%	+42.87%	0
TUDOR INVESTMENT CORP ET AL	Decreased	123,410(-1.2%)	$719,480	0.0%	+10.48%	0
XTX Topco Ltd	New	119,643	$697,519	0.0%	+7.24%	34
MetLife Investment Management, LLC	Decreased	119,103(-13.3%)	$694,370	0.0%	+10.48%	0
Caption Management, LLC	New	115,000	$670,450	0.0%	+7.24%	34
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	110,220(-5.5%)	$642,583	0.0%	+19.35%	0
WELLINGTON MANAGEMENT GROUP LLP	Decreased	100,087(-2.4%)	$583,507	0.0%	-1.78%	0
HSBC HOLDINGS PLC	Increased	98,815(+12.9%)	$581,526	0.0%	+45.05%	27
SEI INVESTMENTS CO	Decreased	98,424(-2.9%)	$573,815	0.0%	+5.62%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Increased	95,934(+14.3%)	$559,295	0.0%	+13.67%	28
LOS ANGELES CAPITAL MANAGEMENT LLC	New	81,128	$406,451	0.0%	+7.24%	33
Brevan Howard Capital Management LP	New	69,423	$404,736	0.0%	+7.24%	33
Arizona State Retirement System	Decreased	67,989(-3.9%)	$396,376	0.0%	+34.05%	0
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	Decreased	69,447(-4.1%)	$386,125	0.0%	+29.55%	0
Police & Firemen's Retirement System of New Jersey	Unchanged	65,211	$380,180	0.0%	+16.75%	0
Quadrature Capital Ltd	New	63,566	$370,590	0.0%	+7.24%	33
CITIGROUP INC	Increased	61,816(+20.6%)	$360,387	0.0%	+17.07%	28
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	60,780	$354,347	0.0%	-16.06%	0
Cerity Partners LLC	Increased	59,359(+5.3%)	$346,063	0.0%	+26.92%	25
NEW YORK STATE COMMON RETIREMENT FUND	Decreased	59,144(-21.9%)	$344,810	0.0%	+45.90%	0
ExodusPoint Capital Management, LP	Decreased	55,731(-58.7%)	$324,912	0.0%	+26.17%	0
ProShare Advisors LLC	Increased	54,531(+11.4%)	$317,917	0.0%	+26.85%	26
KLP KAPITALFORVALTNING AS	Increased	51,600(+3.0%)	$300,828	0.0%	+18.12%	24
LAZARD ASSET MANAGEMENT LLC	Increased	45,257(+119.9%)	$263,848	0.0%	+9.81%	37
VOYA INVESTMENT MANAGEMENT LLC	Unchanged	42,860	$249,874	0.0%	+9.59%	0
VIRGINIA RETIREMENT SYSTEMS ET Al	Increased	41,750(+65.7%)	$243,403	0.0%	+9.17%	34
MERCER GLOBAL ADVISORS INC /ADV	Increased	38,512(+4.7%)	$224,525	0.0%	+26.06%	24
TEACHER RETIREMENT SYSTEM OF TEXAS	Decreased	35,686(-39.1%)	$208,050	0.0%	+26.61%	0
Mariner, LLC	Decreased	35,442(-7.9%)	$206,411	0.0%	+33.05%	0
COMMONWEALTH EQUITY SERVICES, LLC	Decreased	33,350(-14.6%)	$194,430	0.0%	+87.86%	0
Pictet Asset Management Holding SA	Unchanged	32,479	$189,353	0.0%	+41.76%	0
Creative Planning	Increased	28,436(+12.6%)	$165,782	0.0%	+6.85%	25
STRS OHIO	Unchanged	27,500	$160,325	0.0%	-16.06%	0
STIFEL FINANCIAL CORP	New	27,455	$160,063	0.0%	+7.24%	31
Russell Investments Group, Ltd.	Decreased	27,116(-0.3%)	$158,086	0.0%	+41.49%	0
VICTORY CAPITAL MANAGEMENT INC	Increased	26,883(+0.5%)	$156,728	0.0%	+46.61%	22
Focus Partners Wealth	Increased	24,692(+22.9%)	$143,954	0.0%	+18.10%	27
BLAIR WILLIAM & CO/IL	Increased	24,507(+0.0%)	$142,876	0.0%	+9.12%	22
Merit Financial Group, LLC	Increased	24,250(+2.4%)	$141,377	0.0%	+31.63%	23
FARALLON CAPITAL MANAGEMENT LLC	Unchanged	23,000	$134,090	0.0%	-14.79%	0
CAPTRUST FINANCIAL ADVISORS	Decreased	19,947(-8.7%)	$116,291	0.0%	+18.51%	0
XPONANCE LLC	Increased	18,947(+2.5%)	$110,461	0.0%	+48.39%	22
NewEdge Advisors, LLC	Increased	17,909(+1690.9%)	$104,409	0.0%	+10.38%	35
Ensign Peak Advisors, Inc	Decreased	17,500(-68.5%)	$102,025	0.0%	-11.04%	0
BALYASNY ASSET MANAGEMENT L.P.	Decreased	17,222(-94.6%)	$100,404	0.0%	+43.10%	0
Orion Porfolio Solutions, LLC	Decreased	16,305(-1.6%)	$95,058	0.0%	+3.58%	0
CIBC WORLD MARKETS CORP	Decreased	15,854(-45.5%)	$92,429	0.0%	+22.80%	0
PRINCIPAL FINANCIAL GROUP INC	Decreased	14,317(-21.6%)	$83,468	0.0%	-9.55%	0
Steward Partners Investment Advisory, LLC	Increased	14,021(+81.4%)	$81,742	0.0%	-3.47%	33
Integrated Wealth Concepts LLC	Decreased	12,061(-21.0%)	$70,316	0.0%	+52.90%	0
Mirae Asset Global Investments Co., Ltd.	Increased	11,807(+26.7%)	$68,835	0.0%	+33.20%	26
OSAIC HOLDINGS, INC.	Decreased	11,805(-28.9%)	$68,822	0.0%	+25.71%	0
Swiss Life Asset Management Ltd	Increased	11,579(+12.1%)	$67,506	0.0%	+10.12%	24
Vontobel Holding Ltd.	Unchanged	11,470	$66,870	0.0%	+10.48%	0
AMERIPRISE FINANCIAL INC	Increased	11,128(+8.1%)	$64,876	0.0%	+18.29%	15
Sumitomo Mitsui Trust Group, Inc.	New	10,320	$60,166	0.0%	+7.24%	32
Quantinno Capital Management LP	New	10,282	$59,944	0.0%	+7.24%	29
ROYAL BANK OF CANADA	Decreased	7,831(-99.1%)	$46,000	0.0%	+13.20%	0
MAI Capital Management	New	3,047	$17,765	0.0%	+7.24%	26
NISA INVESTMENT ADVISORS, LLC	Decreased	2,846(-20.9%)	$16,592	0.0%	-2.94%	0
Allworth Financial LP	Decreased	2,815(-14.0%)	$16,412	0.0%	+23.06%	0
BROWN BROTHERS HARRIMAN & CO	Increased	1,147(+191.1%)	$6,687	0.0%	+22.56%	18
COMERICA BANK	Unchanged	985	$5,742	0.0%	-3.13%	0
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	New	922	$5,375	0.0%	+7.24%	23
Farther Finance Advisors, LLC	Increased	378(+980.0%)	$2,204	0.0%	+7.53%	13
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	298(-3.3%)	$1,738	0.0%	+17.55%	0
PRICE T ROWE ASSOCIATES INC /MD/	Increased	234,466(+3.1%)	$1,367	0.0%	+21.86%	12
BNP Paribas Asset Management Holding S.A.	Increased	2,970(+39.6%)	$17	0.0%	+40.51%	10
Rockefeller Capital Management L.P.	Increased	6(+500.0%)	$12	0.0%	+7.77%	12
FIFTH THIRD BANCORP	Exited	0(-100.0%)	$832	0.0%	+3.02%	0
MACQUARIE GROUP LTD	Exited	0(-100.0%)	$57.6M	0.0%	-13.46%	0
NOMURA HOLDINGS INC	Exited	0(-100.0%)	$914,616	0.0%	+3.02%	0
IMC-Chicago, LLC	Exited	0(-100.0%)	$323,762	0.0%	+3.02%	0
Aberdeen Group plc	Exited	0(-100.0%)	$4.8M	0.0%	+0.42%	0
HRT FINANCIAL LP	Exited	0(-100.0%)	$3,675	0.0%	+3.02%	0
Virtu Financial LLC	Exited	0(-100.0%)	$72	0.0%	+57.18%	0
Wealthspire Advisors, LLC	Exited	0(-100.0%)	$6,574	0.0%	+3.02%	0
Schonfeld Strategic Advisors LLC	Exited	0(-100.0%)	$897,025	0.0%	+1.55%	0
Jain Global LLC	Exited	0(-100.0%)	$74,385	0.0%	+3.02%	0
Optiver Holding B.V.	Exited	0(-100.0%)	$7,009	0.0%	+6.20%	0
Savant Capital, LLC	Exited	0(-100.0%)	$290,642	0.0%	+14.94%	0
CAPSTONE INVESTMENT ADVISORS, LLC	Exited	0(-100.0%)	$638,135	0.0%	+3.02%	0

ARDELYX INC

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