AYTU BIOPHARMA INC (AYTU) is held by 22 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is VANGUARD CAPITAL MANAGEMENT LLC as of Q1 2026.

Are institutions buying or selling AYTU?

In Q1 2026, 11 institutions opened or increased positions in AYTU BIOPHARMA INC while 4 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on AYTU?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for AYTU BIOPHARMA INC.

How many hedge funds hold AYTU?

22 institutional investors report holding AYTU BIOPHARMA INC (AYTU) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into AYTU?

As of Q1 2026, tracked institutions in AYTU BIOPHARMA INC show 11 buyers versus 4 sellers — net inflows.

AYTU BIOPHARMA INC

AYTU·054754858·US·Common Stock·Healthcare - Drug Manufacturers - Specialty & Generic-Activist

Holders

Avg rating(4 Elite)

$2.1M

Total Value

73% (24)

Fund Consensus

11 buying - 4 selling

Smart Money Verdict

View all

Held by 22 funds

4 elite

Who's Trading

ActivistLLLYTTON LAURENCE W10.0%Feb 17, 2026

ActivistAIAWM Investment Company, Inc.5.8%Feb 13, 2026

ActivistPHPhilotimo Fund, LP0.0%Nov 12, 2025

ActivistSTStonepine Capital Management, LLC9.9%Aug 13, 2025

ActivistNANantahala Capital Management, LLC14.4%Jun 9, 2025

View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
VAVANGUARD CAPITAL MANAGEMENT LLC	New	261,146	$712,929	0.0%	-14.77%	38
TWO SIGMA INVESTMENTS, LP	Increased	121,973(+13.8%)	$332,986	0.0%	+2.29%	27
RENAISSANCE TECHNOLOGIES LLC	Increased	93,723(+4.6%)	$255,864	0.0%	-87.79%	24
GEODE CAPITAL MANAGEMENT, LLC	Increased	92,636(+25.0%)	$252,933	0.0%	-89.69%	19
VFVANGUARD FIDUCIARY TRUST CO	New	47,048	$128,441	0.0%	-14.77%	34
DIMENSIONAL FUND ADVISORS LP	Increased	43,585(+23.3%)	$118,987	0.0%	+14.20%	18
CITADEL ADVISORS LLC	Increased	36,841(+136.9%)	$100,576	0.0%	-13.53%	24
BlackRock, Inc.	Unchanged	22,793	$62,225	0.0%	+39.75%	0
XTX Topco Ltd	Decreased	21,582(-16.5%)	$58,919	0.0%	-11.76%	0
NORTHERN TRUST CORP	Unchanged	19,169	$52,331	0.0%	-11.76%	0
MAI Capital Management	Unchanged	3,575	$9,760	0.0%	+39.75%	0
UBS Group AG	Decreased	1,663(-45.5%)	$4,539	0.0%	+8.80%	0
OSAIC HOLDINGS, INC.	Increased	462(+0.4%)	$1,259	0.0%	-95.38%	8
JPMORGAN CHASE & CO	New	154	$405	0.0%	-14.77%	17
WELLS FARGO & COMPANY/MN	Unchanged	127	$347	0.0%	-16.57%	0
MORGAN STANLEY	Unchanged	125	$341	0.0%	-22.95%	0
GROUP ONE TRADING LLC	Unchanged	37	$101	0.0%	-88.85%	0
BNP PARIBAS FINANCIAL MARKETS	Unchanged	23	$63	0.0%	+39.75%	0
NewEdge Advisors, LLC	Unchanged	21	$57	0.0%	-30.53%	0
Rockefeller Capital Management L.P.	New	10	$27	0.0%	-14.77%	17