AYTU BIOPHARMA INC

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AYTU·054754858·US·equity·Healthcare - Drug Manufacturers - Specialty & Generic-Activist

AYTU (AYTU BIOPHARMA INC) is held by 19 institutional investors as of Q1 2026. Largest holders: TWO SIGMA INVESTMENTS, LP ($332,986), RENAISSANCE TECHNOLOGIES LLC ($255,864), GEODE CAPITAL MANAGEMENT, LLC ($252,933). Net institutional sentiment: Mixed.

19

Holders

Avg rating

$1.3M

Total Value

60% (23)

Fund Consensus

9 buying - 6 selling

Smart Money Verdict

View all

50Mixed MomentumSplit Signals

Institutional (13F)49

Insider (Form 4)

No data

Activist (13D/13G)51

Congressional (STOCK Act)

No data

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See how AYTU's score breaks down across 4 SEC sources

Holder Quality

0

★★★★★

Elite

5

★★★★

Strong

10

★★★

Solid

6

★★

Below

2

★

Weak

Held by 19 funds

Who's Trading

ActivistLLLYTTON LAURENCE W10.0%Feb 17, 2026

ActivistAIAWM Investment Company, Inc.5.8%Feb 13, 2026

ActivistPHPhilotimo Fund, LP0.0%Nov 12, 2025

ActivistSTStonepine Capital Management, LLC9.9%Aug 13, 2025

ActivistNANantahala Capital Management, LLC14.4%Jun 9, 2025

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13F: Mar 31, 2026Insider & Congress: Updated regularly

Positions (19)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
TWO SIGMA INVESTMENTS, LP	Increased	121,973(+13.8%)	$332,986	0.0%	-0.44%	27
RENAISSANCE TECHNOLOGIES LLC	Increased	93,723(+4.6%)	$255,864	0.0%	-88.12%	24
GEODE CAPITAL MANAGEMENT, LLC	Increased	92,636(+25.0%)	$252,933	0.0%	-89.96%	19
DIMENSIONAL FUND ADVISORS LP	Increased	43,585(+23.3%)	$118,987	0.0%	+11.16%	18
CITADEL ADVISORS LLC	Increased	36,841(+136.9%)	$100,576	0.0%	-15.83%	24
BlackRock, Inc.	Unchanged	22,793	$62,225	0.0%	+36.02%	0
XTX Topco Ltd	Decreased	21,582(-16.5%)	$58,919	0.0%	-14.12%	0
NORTHERN TRUST CORP	Unchanged	19,169	$52,331	0.0%	-14.12%	0
MAI Capital Management	Unchanged	3,575	$9,760	0.0%	+36.02%	0
UBS Group AG	Decreased	1,663(-45.5%)	$4,539	0.0%	+5.90%	0
OSAIC HOLDINGS, INC.	Increased	462(+0.4%)	$1,259	0.0%	-95.50%	8
JPMORGAN CHASE & CO	New	154	$405	0.0%	-17.05%	17
WELLS FARGO & COMPANY/MN	Unchanged	127	$347	0.0%	-18.80%	0
MORGAN STANLEY	Unchanged	125	$341	0.0%	-25.00%	0
GROUP ONE TRADING LLC	Unchanged	37	$101	0.0%	-89.14%	0
BNP PARIBAS FINANCIAL MARKETS	Unchanged	23	$63	0.0%	+36.02%	0
Rockefeller Capital Management L.P.	New	10	$27	0.0%	-17.05%	17
JONES FINANCIAL COMPANIES LLLP	Unchanged	1	$3	0.0%	+80.99%	0
TWO SIGMA ADVISERS, LP	Exited	0(-100.0%)	$110,500	0.0%	+49.71%	0
ROYAL BANK OF CANADA	Increased	36(+44.0%)	$0	0.0%	-15.03%	10

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High Conviction Moves-Signal Convergence-Fund Consensus-Double-Down Signals

Data sourced from four SEC data sources: 13F, Form 4, 13D/13G, and STOCK Act. Not financial advice. Full disclaimer