Bicycle Therapeutics plc (BCYC) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling BCYC?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Bicycle Therapeutics plc, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on BCYC?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Bicycle Therapeutics plc.

Is institutional money flowing into BCYC?

65 institutional investors hold Bicycle Therapeutics plc (BCYC). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about BCYC?

Track institutional sentiment and conviction scores for Bicycle Therapeutics plc (BCYC) including Smart Money Verdict and position changes on HoldingsIntel.

Bicycle Therapeutics plc

BCYC·088786108·US·adr·Healthcare - Biotechnology-13D/G

SPONSORED ADS

BCYC (Bicycle Therapeutics plc) is held by 65 institutional investors as of Q4 2025. Largest holders: BAKER BROS. ADVISORS LP ($77.1M), WESTFIELD CAPITAL MANAGEMENT CO LP ($21.4M), Candriam S.C.A. ($8.4M). Net institutional sentiment: Mixed.

Holders

Avg rating(4 Elite)

$153.2M

Total Value

57% (69)

Fund Consensus

33 buying - 25 selling

Smart Money VerdictView all

45Weak MomentumStrong Convergence

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See how BCYC's score breaks down across 4 SEC sources

Held by 65 funds

4 elite

Who's Trading

InsiderHannay Michael Charles FergusonSell $7KApr 2, 2026

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BAKER BROS. ADVISORS LP	Unchanged	10.9M	$77.1M	0.5%	-73.61%	0
WESTFIELD CAPITAL MANAGEMENT CO LP	Increased	3M(+2.1%)	$21.4M	0.1%	-67.35%	29
Candriam S.C.A.	Increased	1.2M(+1.7%)	$8.4M	0.0%	-71.20%	28
PRINCIPAL FINANCIAL GROUP INC	Decreased	1.1M(-0.0%)	$8.1M	0.0%	-58.88%	0
RENAISSANCE TECHNOLOGIES LLC	Increased	566,600(+9.2%)	$4M	0.0%	-61.12%	29
SCHRODER INVESTMENT MANAGEMENT GROUP	New	584,770	$4M	0.0%	-19.12%	37
SILVERCREST ASSET MANAGEMENT GROUP LLC	Unchanged	476,976	$3.4M	0.0%	-55.93%	0
MORGAN STANLEY	Decreased	465,222(-43.5%)	$3.3M	0.0%	-70.26%	0
BlackRock, Inc.	Increased	332,889(+17.9%)	$2.4M	0.0%	-56.57%	21
MILLENNIUM MANAGEMENT LLC	Decreased	326,626(-69.0%)	$2.3M	0.0%	-34.64%	0
Jefferies Financial Group Inc.	Decreased	297,247(-26.0%)	$2.1M	0.0%	-37.32%	0
MOORE CAPITAL MANAGEMENT, LP	Increased	275,000(+120.0%)	$1.9M	0.0%	-25.49%	42
CITADEL ADVISORS LLC	Increased	271,383(+43.6%)	$1.9M	0.0%	-55.97%	35
TD ASSET MANAGEMENT INC	Decreased	147,992(-16.9%)	$1M	0.0%	-76.71%	0
TWO SIGMA ADVISERS, LP	Decreased	146,100(-6.8%)	$1M	0.0%	-26.12%	0
TWO SIGMA INVESTMENTS, LP	Decreased	132,032(-28.4%)	$934,787	0.0%	-26.64%	0
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	127,863(-9.0%)	$869,468	0.0%	-73.85%	0
Walleye Capital LLC	New	111,659	$790,546	0.0%	-19.12%	34
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	108,423(+307.2%)	$767,635	0.0%	-20.39%	40
BANK OF AMERICA CORP /DE/	Decreased	96,401(-83.7%)	$682,519	0.0%	-49.33%	0
Marex Group plc	New	78,406	$555,114	0.0%	-19.12%	34
Point72 Asset Management, L.P.	Decreased	76,779(-82.2%)	$543,595	0.0%	-65.42%	0
STATE STREET CORP	Decreased	70,178(-5.7%)	$496,860	0.0%	-72.46%	0
JANE STREET GROUP, LLC	Decreased	63,190(-38.3%)	$447,385	0.0%	-26.94%	0
State of Tennessee, Department of Treasury	Increased	61,153(+36.4%)	$392,603	0.0%	-24.73%	31
SEI INVESTMENTS CO	Unchanged	49,056	$347,316	0.0%	-30.42%	0
XTX Topco Ltd	Increased	47,674(+309.3%)	$337,532	0.0%	-21.40%	38
Quadrature Capital Ltd	Increased	46,728(+67.5%)	$330,834	0.0%	-23.00%	35
Man Group plc	Increased	42,860(+4.8%)	$303,449	0.0%	-24.92%	25
ALPS ADVISORS INC	Increased	40,995(+69.9%)	$290,245	0.0%	-22.08%	35
MARSHALL WACE, LLP	New	38,795	$274,669	0.0%	-19.12%	32
UBS Group AG	Increased	25,676(+125.8%)	$181,786	0.0%	-47.55%	25
GEODE CAPITAL MANAGEMENT, LLC	Decreased	25,129(-37.1%)	$177,913	0.0%	-67.40%	0
GOLDMAN SACHS GROUP INC	New	24,732	$175,103	0.0%	-19.12%	35
Engineers Gate Manager LP	Increased	24,047(+79.2%)	$170,253	0.0%	-21.94%	34
D. E. Shaw & Co., Inc.	New	21,548	$152,560	0.0%	-19.12%	31
State of New Jersey Common Pension Fund D	Unchanged	20,105	$142,343	0.0%	-27.73%	0
SIMPLEX TRADING, LLC	New	19,986	$141,500	0.0%	-19.12%	31
JPMORGAN CHASE & CO	Increased	18,355(+125.8%)	$129,953	0.0%	-43.00%	24
Federation des caisses Desjardins du Quebec	Unchanged	14,302	$101,131	0.0%	-25.85%	0
PNC FINANCIAL SERVICES GROUP, INC.	Increased	14,138(+8.1%)	$100,097	0.0%	-70.08%	24
HORIZON KINETICS ASSET MANAGEMENT LLC	Decreased	13,792(-4.2%)	$97,647	0.0%	-73.64%	0
Erste Asset Management GmbH	Unchanged	14,000	$94,920	0.0%	-90.60%	0
Cerity Partners LLC	Decreased	13,350(-7.0%)	$94,518	0.0%	-37.85%	0
Vanguard Personalized Indexing Management, LLC	Decreased	12,776(-1.4%)	$90,454	0.0%	-27.73%	0
RAYMOND JAMES FINANCIAL INC	New	12,336	$87,339	0.0%	-19.12%	33
RHUMBLINE ADVISERS	Increased	11,171(+241.1%)	$79,081	0.0%	-35.67%	34
ROYAL BANK OF CANADA	Decreased	10,682(-16.1%)	$76,000	0.0%	-50.02%	0
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS	Unchanged	10,116	$71,621	0.0%	-27.73%	0
Invesco Ltd.	New	10,092	$71,451	0.0%	-19.12%	32
Vontobel Holding Ltd.	New	10,000	$70,800	0.0%	-19.12%	29
Legal & General Group Plc	Decreased	9,054(-95.4%)	$64,102	0.0%	-68.01%	0
NATIXIS	Increased	4,645(+138.6%)	$31,586	0.0%	-57.71%	32
ASSETMARK, INC	Increased	3,628(+0.1%)	$25,686	0.0%	-57.54%	19
Mirae Asset Global Investments Co., Ltd.	Increased	2,248(+25.8%)	$15,916	0.0%	-64.85%	15
CITIGROUP INC	Decreased	1,291(-50.4%)	$9,140	0.0%	-40.14%	0
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	1.2M(-15.4%)	$8,297	0.0%	-76.00%	0
BNP PARIBAS FINANCIAL MARKETS	Increased	1,116(+37.6%)	$7,901	0.0%	-47.48%	15
BNP Paribas Asset Management Holding S.A.	New	568,225	$4,023	0.0%	-19.12%	20
BARCLAYS PLC	Decreased	562(-75.3%)	$3,979	0.0%	-58.76%	0
FMR LLC	Unchanged	316	$2,237	0.0%	-61.08%	0
JONES FINANCIAL COMPANIES LLLP	Unchanged	250	$1,770	0.0%	-62.10%	0
Farther Finance Advisors, LLC	New	218	$1,543	0.0%	-19.12%	17
WELLS FARGO & COMPANY/MN	Unchanged	200	$1,416	0.0%	-24.03%	0
Rockefeller Capital Management L.P.	Unchanged	5	$35	0.0%	-27.73%	0
OSAIC HOLDINGS, INC.	Exited	0(-100.0%)	$132	0.0%	-68.89%	0
Walleye Trading LLC	Exited	0(-100.0%)	$4,876	0.0%	-10.64%	0
Squarepoint Ops LLC	Exited	0(-100.0%)	$102,625	0.0%	-6.58%	0
AMERIPRISE FINANCIAL INC	Exited	0(-100.0%)	$115,883	0.0%	-6.92%	0

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