BICYCLE THERAPEUTICS PLC

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BCYC·088786108·US·ADR·Healthcare - Biotechnology-13D/G

BCYC (BICYCLE THERAPEUTICS PLC) is held by 57 institutional investors as of Q2 2026. Largest holders: BAKER BROS. ADVISORS LP ($46.2M), RENAISSANCE TECHNOLOGIES LLC ($6.5M), MARSHALL WACE, LLP ($3.4M). Net institutional sentiment: Mixed.

57

Holders

(1 Elite)

$81.6M

Total Value

66% (47)

Consensus

31 buying - 16 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)25

Insider (Form 4)39

Activist (13D/13G)50

Congressional (STOCK Act)33

Holder Quality

62

★★★★★

Elite

16

★★★★

Strong

70

★★★

Solid

28

★★

Below

49

★

Weak

Held by 57 funds

1 elite

Who's Trading

Source dates: Price Aug 28, 2026 · Insiders Jul 7, 2026 · Activists Aug 14, 2026 · Congress none

ActivistARArmistice Capital, LLC6.7%Aug 14, 2026

InsiderTAThompson Travis AlvinSell $448.24Jul 6, 2026

InsiderPSPerry Jennifer ScottSell $185.33Jul 6, 2026

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Top Holders

Top Holders (57)History

AllNewIncreasedHeldDecreasedExited

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BAKER BROS. ADVISORS LP	Unchanged	10.9M	$46.2M	0.2%	-79.85%	0
RENAISSANCE TECHNOLOGIES LLC	Increased	1.5M(+56.6%)	$6.5M	0.0%	-49.02%	39
MWMARSHALL WACE, LLP	Increased	797,940(+111.5%)	$3.4M	0.0%	-14.27%	43
Qube Research & Technologies Ltd	Increased	775,567(+151.3%)	$3.3M	0.0%	-11.42%	43
MORGAN STANLEY	Increased	667,269(+7.9%)	$2.8M	0.0%	-70.97%	28
SCHRODER INVESTMENT MANAGEMENT GROUP	Unchanged	615,833	$2.6M	0.0%	-37.63%	0
CITADEL ADVISORS LLC	Increased	554,225(+47.0%)	$2.3M	0.0%	-50.71%	36
MILLENNIUM MANAGEMENT LLC	Increased	553,967(+95.1%)	$2.3M	0.0%	-34.17%	42
TWO SIGMA INVESTMENTS, LP	Increased	434,577(+163.7%)	$1.8M	0.0%	-21.12%	42
JANE STREET GROUP, LLC	Increased	392,163(+79.8%)	$1.7M	0.0%	-20.27%	39
BlackRock, Inc.	Increased	280,386(+0.5%)	$1.2M	0.0%	-66.73%	17
MOORE CAPITAL MANAGEMENT, LP	Unchanged	275,000	$1.2M	0.0%	-43.10%	0
Sculptor Capital LP	New	197,904	$839,113	0.0%	-0.94%	34
Point72 Asset Management, L.P.	Increased	149,936(+15.0%)	$635,729	0.0%	-60.61%	28
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Unchanged	127,863	$542,139	0.0%	-80.03%	0
GOLDMAN SACHS GROUP INC	Increased	121,281(+10.1%)	$514,231	0.0%	-25.66%	18
XTX Topco Ltd	Increased	109,801(+3.2%)	$465,556	0.0%	-31.27%	25
Quadrature Capital Ltd	New	104,092	$441,350	0.0%	-0.94%	33
TD ASSET MANAGEMENT INC	Unchanged	91,992	$390,046	0.0%	-82.21%	0
State of Tennessee, Department of Treasury	Unchanged	61,153	$259,289	0.0%	-42.52%	0

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer