BICYCLE THERAPEUTICS PLC (BCYC) is held by 54 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is BAKER BROS. ADVISORS LP as of Q1 2026.

Are institutions buying or selling BCYC?

In Q1 2026, 30 institutions opened or increased positions in BICYCLE THERAPEUTICS PLC while 25 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on BCYC?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for BICYCLE THERAPEUTICS PLC.

How many hedge funds hold BCYC?

54 institutional investors report holding BICYCLE THERAPEUTICS PLC (BCYC) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into BCYC?

As of Q1 2026, tracked institutions in BICYCLE THERAPEUTICS PLC show 30 buyers versus 25 sellers — net inflows.

BICYCLE THERAPEUTICS PLC

BCYC·088786108·US·ADR·Healthcare - Biotechnology-13D/G

Holders

(4 Elite)

$89.2M

Total Value

55% (55)

Consensus

30 buying - 25 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Held by 54 funds

4 elite

Who's Trading

InsiderLKLee KevinSell $7KJul 6, 2026

InsiderSMSkynner MichaelSell $2KJul 6, 2026

InsiderHFHannay Michael Charles FergusonSell $1KJul 6, 2026

InsiderPSPerry Jennifer ScottSell $185.33Jul 6, 2026

InsiderPSPerry Jennifer ScottSell $1KJul 6, 2026

InsiderTAThompson Travis AlvinSell $448.24Jul 6, 2026

InsiderLKLee KevinSell $25KJul 2, 2026

InsiderSMSkynner MichaelSell $8KJul 2, 2026

ActivistLFLONG FOCUS CAPITAL MANAGEMENT, LLC6.6%May 15, 2026

ActivistARArmistice Capital, LLC6.8%May 15, 2026

View all insider trades View all activist filings

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BAKER BROS. ADVISORS LP	Unchanged	10.9M	$50.5M	0.3%	-78.84%	0
PRINCIPAL FINANCIAL GROUP INC	Increased	1.2M(+2.3%)	$5.5M	0.0%	-66.59%	28
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	1M(-12.3%)	$4.8M	0.0%	-80.75%	0
RENAISSANCE TECHNOLOGIES LLC	Increased	979,300(+72.8%)	$4.5M	0.0%	-58.01%	40
MORGAN STANLEY	Increased	618,327(+32.9%)	$2.9M	0.0%	-71.13%	34
SCHRODER INVESTMENT MANAGEMENT GROUP	Increased	615,833(+5.3%)	$2.7M	0.0%	-34.52%	28
SILVERCREST ASSET MANAGEMENT GROUP LLC	Decreased	428,684(-10.1%)	$2M	0.0%	-64.66%	0
MWMARSHALL WACE, LLP	Increased	377,335(+872.6%)	$1.8M	0.0%	-21.72%	42
CITADEL ADVISORS LLC	Increased	377,085(+39.0%)	$1.7M	0.0%	-58.12%	34
Qube Research & Technologies Ltd	New	308,617	$1.4M	0.0%	-19.82%	35
MILLENNIUM MANAGEMENT LLC	Decreased	283,986(-13.1%)	$1.3M	0.0%	-47.59%	0
BlackRock, Inc.	Decreased	278,992(-16.2%)	$1.3M	0.0%	-65.18%	0
MOORE CAPITAL MANAGEMENT, LP	Unchanged	275,000	$1.3M	0.0%	-40.26%	0
JANE STREET GROUP, LLC	Increased	218,115(+245.2%)	$1M	0.0%	-27.56%	40
TWO SIGMA INVESTMENTS, LP	Increased	164,800(+24.8%)	$764,672	0.0%	-37.89%	30
Point72 Asset Management, L.P.	Increased	130,422(+69.9%)	$605,158	0.0%	-62.06%	36
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Unchanged	127,863	$593,284	0.0%	-79.03%	0
Marex Group Ltd	Increased	115,000(+46.7%)	$533,600	0.0%	-30.95%	33
GOLDMAN SACHS GROUP INC	Increased	110,147(+345.4%)	$511,082	0.0%	-23.86%	39
XTX Topco Ltd	Increased	106,392(+123.2%)	$493,659	0.0%	-28.54%	39