C4 THERAPEUTICS INC (CCCC) is held by 71 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is MORGAN STANLEY as of Q1 2026.

Are institutions buying or selling CCCC?

In Q1 2026, 46 institutions opened or increased positions in C4 THERAPEUTICS INC while 20 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on CCCC?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for C4 THERAPEUTICS INC.

How many hedge funds hold CCCC?

71 institutional investors report holding C4 THERAPEUTICS INC (CCCC) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into CCCC?

As of Q1 2026, tracked institutions in C4 THERAPEUTICS INC show 46 buyers versus 20 sellers — net inflows.

C4 THERAPEUTICS INC

CCCC·12529R107·US·Common Stock·Healthcare - Biotechnology-13D/G

Holders

Avg rating(15 Elite)

$148.1M

Total Value

70% (75)

Fund Consensus

46 buying - 20 selling

Smart Money Verdict

View all

Held by 71 funds

15 elite

Who's Trading

ActivistSMSquadron Master Fund LP5.0%May 19, 2026

Activist

Point72 Asset Management, L.P.0.2%May 15, 2026

ActivistSISirenia Capital Management LP9.9%May 15, 2026

Activist

Wasatch Advisors LP4.7%Apr 22, 2026

ActivistLYLynx1 Capital Management LP7.3%Feb 17, 2026

ActivistOAOrbiMed Advisors LLC0.5%Feb 17, 2026

ActivistSPSoleus Private Equity Fund III, L.P.5.9%Feb 12, 2026

Activist

Morgan Stanley9.3%Feb 11, 2026

InsiderRLREYNO LEONARDSell $22KJan 16, 2026

ActivistBLBain Capital Life Sciences Fund II, L.P.1.1%Oct 24, 2025

View all insider trades View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
MORGAN STANLEY	Increased	9.1M(+1.0%)	$23.9M	0.0%	+32.84%	29
RA CAPITAL MANAGEMENT, L.P.	Unchanged	8M	$21M	0.2%	+107.14%	0
VAVANGUARD CAPITAL MANAGEMENT LLC	New	3.9M	$10.2M	0.0%	+37.63%	38
TWO SIGMA INVESTMENTS, LP	Increased	3M(+101.1%)	$8M	0.0%	+18.36%	44
WASATCH ADVISORS LP	Decreased	3M(-31.8%)	$7.8M	0.1%	-62.06%	0
JPMORGAN CHASE & CO	Increased	3.2M(+541x)	$7.6M	0.0%	+37.61%	44
CITADEL ADVISORS LLC	Increased	2.5M(+460.7%)	$6.6M	0.0%	+43.89%	44
RENAISSANCE TECHNOLOGIES LLC	Increased	2.5M(+53.6%)	$6.5M	0.0%	+91.65%	38
GOLDMAN SACHS GROUP INC	Increased	2.4M(+119.2%)	$6.3M	0.0%	+51.75%	44
BANK OF AMERICA CORP /DE/	Decreased	2.4M(-1.2%)	$6.2M	0.0%	+30.38%	0
BlackRock, Inc.	Increased	2M(+4.0%)	$5.4M	0.0%	+22.78%	28
MILLENNIUM MANAGEMENT LLC	Increased	1.4M(+17.2%)	$3.7M	0.0%	+103.42%	31
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	1.3M(-27.5%)	$3.4M	0.0%	+95.48%	0
JANE STREET GROUP, LLC	Increased	1.2M(+42.5%)	$3.3M	0.0%	+86.58%	35
DED. E. Shaw & Co., Inc.	Increased	1.1M(+1905.2%)	$2.8M	0.0%	+38.18%	42
GEODE CAPITAL MANAGEMENT, LLC	Decreased	951,043(-3.8%)	$2.5M	0.0%	-60.59%	0
WELLS FARGO & COMPANY/MN	Increased	867,911(+7.3%)	$2.3M	0.0%	+99.78%	28
CONGRESS ASSET MANAGEMENT CO	New	830,624	$2.2M	0.0%	0.00%	36
Qube Research & Technologies Ltd	Increased	752,114(+159.1%)	$2M	0.0%	+55.58%	42
VFVANGUARD FIDUCIARY TRUST CO	New	484,131	$1.3M	0.0%	+37.63%	35