Catalyst Pharmaceuticals, Inc. (CPRX) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling CPRX?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Catalyst Pharmaceuticals, Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on CPRX?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Catalyst Pharmaceuticals, Inc..

Is institutional money flowing into CPRX?

166 institutional investors hold Catalyst Pharmaceuticals, Inc. (CPRX). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about CPRX?

Track institutional sentiment and conviction scores for Catalyst Pharmaceuticals, Inc. (CPRX) including Smart Money Verdict and position changes on HoldingsIntel.

Catalyst Pharmaceuticals, Inc.

CPRX·14888U101·US·equity·Healthcare - Biotechnology-13D/G

CPRX (Catalyst Pharmaceuticals, Inc.) is held by 166 institutional investors as of Q4 2025. Largest holders: BlackRock, Inc. ($434.7M), VANGUARD GROUP INC ($196.8M), STATE STREET CORP ($161.2M). Net institutional sentiment: Mixed.

166

Holders

Avg rating(12 Elite)

$2B

Total Value

46% (177)

Fund Consensus

78 buying - 91 selling

Smart Money VerdictView all

39Weak MomentumSplit Signals

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See how CPRX's score breaks down across 4 SEC sources

Held by 166 funds

12 elite

Who's Trading

ActivistThe Vanguard Group0.0%Mar 26, 2026

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	18.6M(+2.3%)	$434.7M	0.0%	+13.24%	32
VANGUARD GROUP INC	Decreased	8.4M(-3.2%)	$196.8M	0.0%	+21.22%	0
STATE STREET CORP	Increased	6.9M(+7.8%)	$161.2M	0.0%	+35.91%	33
Fundsmith LLP	Unchanged	3.4M	$78.5M	0.5%	+3.07%	0
AMERICAN CENTURY COMPANIES INC	Increased	3M(+19.7%)	$70.6M	0.0%	+12.49%	35
DIMENSIONAL FUND ADVISORS LP	Increased	3M(+21.9%)	$69.9M	0.0%	+32.50%	36
MORGAN STANLEY	Increased	2.9M(+59.1%)	$68.5M	0.0%	+14.63%	42
GEODE CAPITAL MANAGEMENT, LLC	Increased	2.9M(+0.3%)	$67.7M	0.0%	+166.21%	30
RENAISSANCE TECHNOLOGIES LLC	Decreased	2.7M(-25.2%)	$61.9M	0.1%	+49.82%	0
BANK OF AMERICA CORP /DE/	Decreased	2.2M(-4.0%)	$51.3M	0.0%	+10.70%	0
ROYCE & ASSOCIATES LP	Decreased	1.9M(-6.1%)	$44.6M	0.5%	+80.63%	0
JANUS HENDERSON GROUP PLC	Increased	1.7M(+200.6%)	$40.1M	0.0%	+8.17%	47
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	Increased	1.6M(+23.9%)	$37.7M	0.0%	+8.84%	35
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	1.4M(+1.8%)	$31.7M	0.0%	+116.48%	29
Invesco Ltd.	Increased	1.3M(+4.9%)	$30.2M	0.0%	+53.13%	30
Boston Partners	Decreased	1.2M(-4.6%)	$28.5M	0.0%	+48.51%	0
NORTHERN TRUST CORP	Decreased	1.2M(-4.1%)	$28.3M	0.0%	+234.85%	0
MILLENNIUM MANAGEMENT LLC	Decreased	993,647(-15.7%)	$23.2M	0.0%	+23.54%	0
GOLDMAN SACHS GROUP INC	Decreased	979,543(-2.8%)	$22.9M	0.0%	+11.49%	0
VICTORY CAPITAL MANAGEMENT INC	Increased	884,605(+111.9%)	$20.6M	0.0%	+18.36%	46
RAYMOND JAMES FINANCIAL INC	Increased	841,914(+8.9%)	$19.6M	0.0%	+8.74%	31
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	New	778,591	$18.2M	0.0%	+2.71%	39
Legal & General Group Plc	Increased	776,172(+0.3%)	$18.1M	0.0%	+29.77%	28
Bank of New York Mellon Corp	Decreased	700,661(-0.5%)	$16.4M	0.0%	+171.59%	0
PRINCIPAL FINANCIAL GROUP INC	Increased	683,678(+7.0%)	$16M	0.0%	+68.54%	30
FEDERATED HERMES, INC.	Increased	663,754(+70.5%)	$15.5M	0.0%	+10.62%	42
UBS Group AG	Increased	648,987(+9.3%)	$15.1M	0.0%	+20.82%	31
GLENMEDE TRUST CO NA	Increased	618,218(+619.0%)	$14.4M	0.1%	+7.58%	45
Swedbank AB	Unchanged	616,132	$14.4M	0.0%	-3.12%	0
MetLife Investment Management, LLC	Decreased	594,073(-19.7%)	$13.9M	0.1%	+6.53%	0
VOYA INVESTMENT MANAGEMENT LLC	Increased	567,441(+27.1%)	$13.2M	0.0%	+13.05%	35
PUBLIC SECTOR PENSION INVESTMENT BOARD	Decreased	492,939(-4.6%)	$11.5M	0.0%	+26.18%	0
Qube Research & Technologies Ltd	Decreased	487,135(-40.7%)	$11.4M	0.0%	+18.67%	0
Nuveen, LLC	Decreased	418,521(-22.8%)	$9.8M	0.0%	-0.52%	0
Pacer Advisors, Inc.	Decreased	393,733(-36.6%)	$9.2M	0.0%	+51.62%	0
JUPITER ASSET MANAGEMENT LTD	Decreased	390,368(-2.7%)	$9.1M	0.1%	+59.56%	0
Aberdeen Group plc	Decreased	387,910(-38.7%)	$9.1M	0.0%	+6.80%	0
JPMORGAN CHASE & CO	Decreased	369,839(-2.4%)	$8.6M	0.0%	+12.81%	0
Allianz Asset Management GmbH	Decreased	366,757(-54.0%)	$8.6M	0.0%	+6.21%	0
PRUDENTIAL FINANCIAL INC	Decreased	364,824(-9.4%)	$8.5M	0.0%	+56.60%	0
BARCLAYS PLC	Decreased	358,175(-4.0%)	$8.4M	0.0%	+24.98%	0
FMR LLC	Decreased	343,737(-5.1%)	$8M	0.0%	+4.87%	0
RHUMBLINE ADVISERS	Decreased	313,414(-5.1%)	$7.3M	0.0%	+122.14%	0
CITADEL ADVISORS LLC	Decreased	308,471(-22.5%)	$7.2M	0.0%	+12.55%	0
AQR CAPITAL MANAGEMENT LLC	Decreased	303,651(-9.9%)	$7.1M	0.0%	+82.31%	0
Brandywine Global Investment Management, LLC	Decreased	300,116(-3.5%)	$7M	0.0%	+22.35%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	279,281(+0.7%)	$6.5M	0.0%	+27.48%	27
JANE STREET GROUP, LLC	Increased	266,253(+91.4%)	$6.2M	0.0%	+1.48%	43
Skandinaviska Enskilda Banken AB (publ)	Decreased	263,353(-21.5%)	$6.1M	0.0%	+16.58%	0
Trexquant Investment LP	Increased	249,094(+100.3%)	$5.8M	0.1%	+12.61%	44
Swiss National Bank	Increased	229,300(+2.0%)	$5.4M	0.0%	+217.84%	28
AMERIPRISE FINANCIAL INC	Decreased	215,922(-11.0%)	$5M	0.0%	+107.78%	0
Man Group plc	Decreased	188,784(-59.3%)	$4.4M	0.0%	+50.09%	0
VOLORIDGE INVESTMENT MANAGEMENT, LLC	Decreased	188,184(-24.3%)	$4.4M	0.0%	+22.35%	0
STIFEL FINANCIAL CORP	Increased	177,025(+77.0%)	$4.1M	0.0%	+5.27%	41
Universal- Beteiligungs- und Servicegesellschaft mbH	Increased	167,763(+30.0%)	$3.9M	0.0%	+10.83%	34
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	164,212(+145.1%)	$3.8M	0.0%	+7.15%	43
ROYAL BANK OF CANADA	Decreased	161,658(-10.0%)	$3.8M	0.0%	+8.29%	0
WELLS FARGO & COMPANY/MN	Increased	158,702(+37.9%)	$3.7M	0.0%	+14.18%	35
Rafferty Asset Management, LLC	Decreased	155,036(-1.3%)	$3.6M	0.0%	+54.47%	0
FRANKLIN RESOURCES INC	Decreased	153,937(-2.4%)	$3.6M	0.0%	+31.64%	0
DEUTSCHE BANK AG\	Decreased	151,587(-19.3%)	$3.5M	0.0%	+47.20%	0
Woodline Partners LP	Increased	150,647(+0.1%)	$3.5M	0.0%	+49.99%	26
Assenagon Asset Management S.A.	Decreased	138,738(-3.7%)	$3.2M	0.0%	+3.47%	0
LOS ANGELES CAPITAL MANAGEMENT LLC	Decreased	136,599(-15.9%)	$2.9M	0.0%	+47.79%	0
STATE OF WISCONSIN INVESTMENT BOARD	Increased	121,419(+68.6%)	$2.8M	0.0%	+45.17%	39
Russell Investments Group, Ltd.	Decreased	121,411(-7.4%)	$2.8M	0.0%	+107.40%	0
ALLIANCEBERNSTEIN L.P.	Decreased	118,620(-3.8%)	$2.8M	0.0%	+107.64%	0
Sanctuary Advisors, LLC	Increased	114,797(+94.0%)	$2.7M	0.0%	+10.93%	42
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Decreased	109,999(-0.1%)	$2.6M	0.0%	+403.54%	0
Empowered Funds, LLC	New	95,557	$2.2M	0.0%	+2.71%	36
FIRST TRUST ADVISORS LP	Decreased	91,342(-50.7%)	$2.1M	0.0%	+43.22%	0
ASSETMARK, INC	Decreased	86,137(-3.5%)	$2M	0.0%	+53.61%	0
Cresset Asset Management, LLC	Decreased	83,969(-9.8%)	$2M	0.0%	+8.53%	0
NEW YORK STATE COMMON RETIREMENT FUND	Unchanged	83,111	$1.9M	0.0%	+27.44%	0
Fisher Asset Management, LLC	Decreased	82,832(-0.4%)	$1.9M	0.0%	+304.92%	0
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	Decreased	77,433(-3.2%)	$1.8M	0.0%	+43.28%	0
SEI INVESTMENTS CO	Increased	77,072(+0.6%)	$1.8M	0.0%	+52.10%	26
KLP KAPITALFORVALTNING AS	Increased	72,600(+85.7%)	$1.7M	0.0%	+8.16%	40
Creative Planning	Increased	69,927(+244.7%)	$1.6M	0.0%	+9.92%	41
EXCHANGE TRADED CONCEPTS, LLC	Increased	69,787(+10.8%)	$1.6M	0.0%	+20.62%	28
INTECH INVESTMENT MANAGEMENT LLC	Increased	69,447(+27.6%)	$1.6M	0.0%	+11.46%	32
LPL Financial LLC	Increased	66,050(+2.4%)	$1.5M	0.0%	+28.84%	26
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	62,768(+1.5%)	$1.5M	0.0%	+46.09%	26
ENVESTNET ASSET MANAGEMENT INC	Decreased	62,713(-36.9%)	$1.5M	0.0%	+16.46%	0
Gotham Asset Management, LLC	Decreased	61,965(-56.2%)	$1.4M	0.0%	+19.73%	0
HSBC HOLDINGS PLC	Increased	57,929(+91.9%)	$1.4M	0.0%	+13.38%	40
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	56,157(-5.1%)	$1.3M	0.0%	+193.39%	0
Cetera Investment Advisers	Increased	56,036(+6.8%)	$1.3M	0.0%	+19.64%	27
LAZARD ASSET MANAGEMENT LLC	Increased	55,079(+11.7%)	$1.3M	0.0%	+15.20%	28
Verition Fund Management LLC	New	53,944	$1.3M	0.0%	+2.71%	35
CITIGROUP INC	Increased	51,697(+2.9%)	$1.2M	0.0%	+10.81%	26
WELLINGTON MANAGEMENT GROUP LLP	Decreased	49,912(-5.8%)	$1.2M	0.0%	+22.30%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Increased	48,643(+28.4%)	$1.1M	0.0%	+39.77%	31
Engineers Gate Manager LP	Decreased	48,139(-66.5%)	$1.1M	0.0%	+17.13%	0
GUGGENHEIM CAPITAL LLC	Increased	47,626(+285.6%)	$1.1M	0.0%	+7.17%	41
State of Tennessee, Department of Treasury	Decreased	45,112(-8.7%)	$1.1M	0.0%	+75.87%	0
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	44,529	$1M	0.0%	+82.59%	0
STRS OHIO	Decreased	42,000(-11.2%)	$980,280	0.0%	+216.49%	0
State of New Jersey Common Pension Fund D	Decreased	39,686(-61.6%)	$926,271	0.0%	+2.09%	0
Kestra Advisory Services, LLC	Decreased	39,159(-0.1%)	$913,971	0.0%	+22.35%	0
VIRGINIA RETIREMENT SYSTEMS ET Al	Increased	38,600(+2.4%)	$900,924	0.0%	+34.53%	25
Wealthspire Advisors, LLC	Increased	37,160(+0.9%)	$867,315	0.0%	+251.74%	25
CAPTRUST FINANCIAL ADVISORS	Increased	34,560(+76.0%)	$806,630	0.0%	+6.63%	37
Cerity Partners LLC	Increased	32,491(+0.7%)	$758,339	0.0%	+49.66%	25
Arizona State Retirement System	Decreased	32,230(-5.9%)	$752,248	0.0%	+196.08%	0
YOUSIF CAPITAL MANAGEMENT, LLC	Decreased	31,969(-11.6%)	$747,435	0.0%	+84.35%	0
BNP PARIBAS FINANCIAL MARKETS	Decreased	31,388(-12.0%)	$732,596	0.0%	+19.20%	0
Freestone Grove Partners LP	Decreased	30,914(-49.1%)	$721,533	0.0%	+22.35%	0
Police & Firemen's Retirement System of New Jersey	Decreased	30,683(-6.8%)	$716,141	0.0%	+14.47%	0
Rockefeller Capital Management L.P.	Increased	259,938(+1033.7%)	$692,732	0.0%	+4.56%	40
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS	Decreased	28,603(-2.4%)	$667,594	0.0%	+52.77%	0
Allworth Financial LP	Decreased	28,589(-2.4%)	$667,268	0.0%	+13.39%	0
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	Increased	29,504(+1.0%)	$666,204	0.0%	+20.79%	25
Merit Financial Group, LLC	New	28,001	$653,543	0.0%	+2.71%	34
Squarepoint Ops LLC	Decreased	27,629(-74.6%)	$644,861	0.0%	+22.84%	0
Brevan Howard Capital Management LP	Increased	27,056(+28.4%)	$631,487	0.0%	+9.34%	31
EP Wealth Advisors, LLC	Increased	26,972(+123.6%)	$629,526	0.0%	+6.31%	39
COMERICA BANK	Decreased	26,637(-65.4%)	$621,708	0.0%	+52.63%	0
Lido Advisors, LLC	Unchanged	28,505	$561,549	0.0%	+40.50%	0
HighTower Advisors, LLC	Increased	23,844(+63.3%)	$556,525	0.0%	+13.91%	35
ALPS ADVISORS INC	Increased	23,032(+0.9%)	$537,567	0.0%	+92.88%	24
ProShare Advisors LLC	Increased	22,499(+3.2%)	$525,127	0.0%	+49.87%	25
Allspring Global Investments Holdings, LLC	Increased	22,155(+9.7%)	$512,889	0.0%	+33.33%	27
Magnetar Financial LLC	New	21,206	$494,948	0.0%	+2.71%	33
AVIVA PLC	Decreased	20,996(-13.0%)	$490,047	0.0%	+38.05%	0
OMERS ADMINISTRATION Corp	Decreased	20,557(-7.0%)	$479,800	0.0%	+22.35%	0
Envestnet Portfolio Solutions, Inc.	Decreased	20,304(-0.9%)	$473,895	0.0%	+4.63%	0
Walleye Capital LLC	New	20,139	$470,044	0.0%	+2.71%	33
Pictet Asset Management Holding SA	Increased	19,774(+12.2%)	$461,525	0.0%	+55.09%	27
Amundi	Decreased	18,685(-9.0%)	$436,108	0.0%	+25.39%	0
OSAIC HOLDINGS, INC.	Decreased	17,534(-32.3%)	$409,169	0.0%	+21.66%	0
BANQUE PICTET & CIE SA	Decreased	17,429(-19.0%)	$406,793	0.0%	-3.12%	0
TEACHER RETIREMENT SYSTEM OF TEXAS	Decreased	17,196(-39.5%)	$401,355	0.0%	+82.55%	0
COMMONWEALTH EQUITY SERVICES, LLC	Increased	16,080(+6.1%)	$375,308	0.0%	+36.71%	25
Mariner, LLC	New	14,935	$348,615	0.0%	+2.71%	33
CANADA PENSION PLAN INVESTMENT BOARD	New	14,300	$333,762	0.0%	+2.71%	33
CAPSTONE INVESTMENT ADVISORS, LLC	New	14,242	$332,408	0.0%	+2.71%	33
XPONANCE LLC	Decreased	13,559(-4.0%)	$316,467	0.0%	+21.69%	0
MARSHALL WACE, LLP	Decreased	13,227(-45.1%)	$308,719	0.0%	+9.83%	0
MML INVESTORS SERVICES, LLC	Decreased	13,208(-53.7%)	$308,275	0.0%	+12.21%	0
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	Increased	13,205(+2.5%)	$308,205	0.0%	+75.22%	24
Swiss Life Asset Management Ltd	New	12,093	$282,251	0.0%	+2.71%	32
Quantinno Capital Management LP	New	12,091	$282,204	0.0%	+2.71%	32
O'SHAUGHNESSY ASSET MANAGEMENT, LLC	Decreased	11,449(-37.0%)	$267,220	0.0%	+17.86%	0
D. E. Shaw & Co., Inc.	Decreased	10,780(-89.8%)	$251,605	0.0%	+5.35%	0
PNC FINANCIAL SERVICES GROUP, INC.	Increased	10,080(+7.6%)	$235,266	0.0%	+23.95%	25
BANK OF MONTREAL /CAN/	New	9,804	$228,825	0.0%	+2.71%	32
MACKENZIE FINANCIAL CORP	New	9,019	$209,639	0.0%	+2.71%	32
Neuberger Berman Group LLC	Decreased	8,609(-95.6%)	$200,934	0.0%	-0.60%	0
Ensign Peak Advisors, Inc	Decreased	7,160(-65.9%)	$167,114	0.0%	+54.37%	0
JONES FINANCIAL COMPANIES LLLP	Increased	5,594(+37.8%)	$130,564	0.0%	+7.67%	29
NISA INVESTMENT ADVISORS, LLC	Decreased	5,330(-2.2%)	$124,402	0.0%	+50.14%	0
Asset Management One Co., Ltd.	New	4,613	$110,989	0.0%	+2.71%	30
CIBC Private Wealth Group LLC	Decreased	4,091(-26.0%)	$95,484	0.0%	+39.65%	0
NATIONAL BANK OF CANADA /FI/	Increased	2,475(+12.7%)	$57,717	0.0%	+42.64%	23
US BANCORP \DE\	Decreased	2,175(-66.9%)	$50,764	0.0%	+35.93%	0
Farther Finance Advisors, LLC	Decreased	1,544(-5.9%)	$36,037	0.0%	+19.04%	0
HUNTINGTON NATIONAL BANK	Decreased	1,164(-15.4%)	$27,169	0.0%	+7.25%	0
PRICE T ROWE ASSOCIATES INC /MD/	Increased	748,781(+0.7%)	$17,477	0.0%	+35.22%	18
Steward Partners Investment Advisory, LLC	Unchanged	734	$17,131	0.0%	-2.70%	0
FIFTH THIRD BANCORP	Increased	590(+3.3%)	$13,771	0.0%	+22.30%	13
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	Increased	400(+128.6%)	$9,336	0.0%	+6.46%	19
MAI Capital Management	Unchanged	118	$2,755	0.0%	+9.83%	0
PICTON MAHONEY ASSET MANAGEMENT	Unchanged	55	$1,284	0.0%	+22.29%	0
BNP Paribas Asset Management Holding S.A.	Increased	1,756(+36.3%)	$41	0.0%	+8.05%	10
ExodusPoint Capital Management, LP	Exited	0(-100.0%)	$3M	0.0%	+15.21%	0
MATHER GROUP, LLC.	Exited	0(-100.0%)	$2,600	0.0%	+19.13%	0
JENNISON ASSOCIATES LLC	Exited	0(-100.0%)	$780,613	0.0%	+19.13%	0
Optiver Holding B.V.	Exited	0(-100.0%)	$7,171	0.0%	+19.13%	0
Alyeska Investment Group, L.P.	Exited	0(-100.0%)	$5.4M	0.0%	+19.13%	0
NATIXIS	Exited	0(-100.0%)	$1.7M	0.0%	+19.13%	0
JACOBS LEVY EQUITY MANAGEMENT, INC	Exited	0(-100.0%)	$6M	0.0%	+52.17%	0
Tidal Investments LLC	Exited	0(-100.0%)	$867,588	0.0%	+37.95%	0
CIBC WORLD MARKETS CORP	Exited	0(-100.0%)	$309,551	0.0%	+0.48%	0
MACQUARIE GROUP LTD	Exited	0(-100.0%)	$15M	0.0%	+5.64%	0
CAPITAL FUND MANAGEMENT S.A.	Exited	0(-100.0%)	$2.3M	0.0%	+34.14%	0

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