Definium Therapeutics, Inc.

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DFTX·24477V105·US·Common Stock·Healthcare - Biotechnology-13D/G

DFTX (Definium Therapeutics, Inc.) is held by 160 institutional investors as of Q2 2026. Largest holders: BlackRock, Inc. ($528.4M), Avoro Capital Advisors LLC ($338.2M), DRIEHAUS CAPITAL MANAGEMENT LLC ($322M). Net institutional sentiment: Bullish.

160

Holders

(16 Elite)

$3.9B

Total Value

74% (166)

Consensus

123 buying - 43 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)49

Insider (Form 4)56

Activist (13D/13G)69

Congressional (STOCK Act)77

Holder Quality

19

★★★★★

Elite

27

★★★★

Strong

27

★★★

Solid

65

★★

Below

60

★

Weak

Held by 160 funds

16 elite

Who's Trading

Source dates: Price Aug 27, 2026 · Insiders Mar 26, 2026 · Activists Aug 14, 2026 · Congress none

ActivistDRIEHAUS CAPITAL MANAGEMENT LLC5.4%Aug 14, 2026

ActivistCOCommodore Capital LP1.8%Aug 14, 2026

ActivistDTDeep Track Capital, LP3.0%May 15, 2026

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Top Holders

Top Holders (160)History

AllNewIncreasedHeldDecreasedExited

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	11.2M(+32.5%)	$528.4M	0.0%	+75.91%	40
Avoro Capital Advisors LLC	Increased	7.2M(+43.8%)	$338.2M	3.0%	+64.38%	78
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	6.8M(+15.8%)	$322M	1.9%	+148.72%	56
Capital World Investors	New	5.4M	$252.5M	0.0%	-6.95%	43
FMR LLC	Increased	4.8M(+162.7%)	$223.6M	0.0%	+22.04%	49
GEODE CAPITAL MANAGEMENT, LLC	Increased	3.6M(+46.1%)	$171.5M	0.0%	+62.44%	41
STATE STREET CORP	Increased	3.1M(+24.0%)	$144.2M	0.0%	+87.27%	37
Capital International Investors	New	3M	$139.4M	0.0%	-6.95%	42
WELLINGTON MANAGEMENT GROUP LLP	Increased	2.9M(+126.1%)	$138.8M	0.0%	+28.52%	49
GOLDMAN SACHS GROUP INC	Increased	1.8M(+7.5%)	$84.7M	0.0%	+121.80%	32
CITADEL ADVISORS LLC	Increased	1.7M(+26.6%)	$79.4M	0.0%	+83.42%	37
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	1.6M(+88.9%)	$77.5M	0.0%	+38.94%	47
RA CAPITAL MANAGEMENT, L.P.	New	1.5M	$70.6M	0.6%	-6.95%	58
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	1.5M(+35.5%)	$69.9M	0.0%	+72.46%	38
MWMARSHALL WACE, LLP	Increased	1.3M(+8.2%)	$61.1M	0.0%	+181.93%	32
NORTHERN TRUST CORP	Increased	1.2M(+46.3%)	$55M	0.0%	+62.21%	40
AMERIPRISE FINANCIAL INC	Increased	1.1M(+18.8%)	$54M	0.0%	+95.97%	35
Nuveen, LLC	Increased	1.1M(+58.3%)	$52M	0.0%	+53.57%	42
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	1.1M(+34.0%)	$51M	0.0%	+74.14%	38
Woodline Partners LP	Increased	1M(+33.3%)	$47.2M	0.1%	+74.90%	45

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DFTXDefinium Therapeutics, Inc.

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer