FULCRUM THERAPEUTICS INC (FULC) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling FULC?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for FULCRUM THERAPEUTICS INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on FULC?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for FULCRUM THERAPEUTICS INC.

Is institutional money flowing into FULC?

93 institutional investors hold FULCRUM THERAPEUTICS INC (FULC). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about FULC?

Track institutional sentiment and conviction scores for FULCRUM THERAPEUTICS INC (FULC) including Smart Money Verdict and position changes on HoldingsIntel.

FULCRUM THERAPEUTICS INC

FULC·359616109·US·equity·Healthcare - Biotechnology-13D/G

FULC (FULCRUM THERAPEUTICS INC) is held by 93 institutional investors as of Q4 2025. Largest holders: RA CAPITAL MANAGEMENT, L.P. ($68.5M), BlackRock, Inc. ($48.2M), VANGUARD GROUP INC ($40.3M). Net institutional sentiment: Mixed.

Holders

Avg rating(4 Elite)

$380.4M

Total Value

58% (97)

Fund Consensus

52 buying - 33 selling

Smart Money Verdict- Q4 2025View all

41Weak MomentumSplit Signals

Held by 93 funds

4 elite

Who's Trading

ActivistThe Vanguard Group0.0%Mar 26, 2026

Activist

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Decreased	6.1M(-40.8%)	$68.5M	0.7%	+16.06%	0
BlackRock, Inc.	Increased	4.3M(+15.0%)	$48.2M	0.0%	+41.80%	34
VANGUARD GROUP INC	Increased	3.6M(+18.7%)	$40.3M	0.0%	+58.63%	34
Point72 Asset Management, L.P.	New	2.4M	$27.1M	0.0%	-30.60%	40
D. E. Shaw & Co., Inc.	Increased	1.9M(+32.0%)	$21.6M	0.0%	-1.54%	36
ADAGE CAPITAL PARTNERS GP, L.L.C.	Decreased	1.7M(-30.1%)	$19.2M	0.0%	+47.87%	0
Aberdeen Group plc	Increased	1.3M(+809.0%)	$14.2M	0.0%	-28.28%	45
CITADEL ADVISORS LLC	Increased	1.2M(+41.2%)	$13.7M	0.0%	-11.31%	37
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.1M(+10.1%)	$12.5M	0.0%	-5.16%	31
DIMENSIONAL FUND ADVISORS LP	Decreased	1.1M(-19.1%)	$11.9M	0.0%	+33.62%	0
STATE STREET CORP	Decreased	1M(-5.4%)	$11.4M	0.0%	+44.03%	0
BALYASNY ASSET MANAGEMENT L.P.	Decreased	970,439(-33.1%)	$11M	0.0%	+8.98%	0
Connor, Clark & Lunn Investment Management Ltd.	Increased	582,377(+51.6%)	$6.6M	0.0%	+3.18%	38
NORTHERN TRUST CORP	Decreased	552,220(-2.8%)	$6.2M	0.0%	+47.25%	0
JANE STREET GROUP, LLC	Increased	493,750(+53.6%)	$5.6M	0.0%	-16.83%	38
Invesco Ltd.	Increased	417,189(+236.8%)	$4.7M	0.0%	-20.77%	43
Qube Research & Technologies Ltd	New	392,489	$4.4M	0.0%	-30.60%	37
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	388,896(+16.6%)	$4.4M	0.0%	+38.52%	31
Trexquant Investment LP	Increased	355,547(+1591.9%)	$4M	0.0%	-29.62%	43
GOLDMAN SACHS GROUP INC	Decreased	323,879(-44.8%)	$3.7M	0.0%	+25.96%	0
DEUTSCHE BANK AG\	Increased	287,096(+0.6%)	$3.2M	0.0%	+15.69%	27
DRIEHAUS CAPITAL MANAGEMENT LLC	New	243,388	$2.8M	0.0%	-30.60%	36
BANK OF AMERICA CORP /DE/	Increased	231,177(+57.0%)	$2.6M	0.0%	-11.03%	37
WELLS FARGO & COMPANY/MN	Increased	166,395(+411.9%)	$1.9M	0.0%	-23.41%	42
MORGAN STANLEY	Decreased	165,623(-32.1%)	$1.9M	0.0%	+50.83%	0
AMERICAN CENTURY COMPANIES INC	Increased	157,672(+3.6%)	$1.8M	0.0%	+22.13%	27
WELLINGTON MANAGEMENT GROUP LLP	Decreased	146,427(-18.4%)	$1.7M	0.0%	+4.05%	0
BARCLAYS PLC	Increased	132,541(+47.9%)	$1.5M	0.0%	+10.11%	35
Bank of New York Mellon Corp	Decreased	116,906(-1.9%)	$1.3M	0.0%	+28.41%	0
Nuveen, LLC	Unchanged	112,203	$1.3M	0.0%	+161.46%	0
Walleye Capital LLC	New	108,434	$1.2M	0.0%	-30.60%	35
UBS Group AG	Decreased	102,967(-65.8%)	$1.2M	0.0%	-0.32%	0
MARSHALL WACE, LLP	New	102,921	$1.2M	0.0%	-30.60%	35
AMERIPRISE FINANCIAL INC	Decreased	100,675(-19.2%)	$1.1M	0.0%	-9.23%	0
PRINCIPAL FINANCIAL GROUP INC	Increased	97,688(+46.8%)	$1.1M	0.0%	-17.34%	34
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	87,930(+64.1%)	$994,488	0.0%	+4.78%	36
STATE OF WISCONSIN INVESTMENT BOARD	Increased	86,499(+533.0%)	$978,304	0.0%	-27.92%	40
Verition Fund Management LLC	New	74,691	$844,755	0.0%	-30.60%	34
CITIGROUP INC	Increased	67,102(+9245.7%)	$758,924	0.0%	-30.16%	40
Squarepoint Ops LLC	Increased	65,852(+269.4%)	$744,786	0.0%	-23.53%	40
NEW YORK STATE COMMON RETIREMENT FUND	Increased	57,725(+340.6%)	$652,870	0.0%	-22.64%	39
RHUMBLINE ADVISERS	Decreased	55,713(-19.7%)	$630,103	0.0%	+26.01%	0
MILLENNIUM MANAGEMENT LLC	Decreased	54,431(-63.9%)	$615,615	0.0%	+11.26%	0
XTX Topco Ltd	New	51,802	$585,881	0.0%	-30.60%	34
Brevan Howard Capital Management LP	Increased	48,900(+219.6%)	$559,416	0.0%	-25.08%	39
STRS OHIO	Decreased	49,300(-36.7%)	$557,583	0.0%	+99.44%	0
FRANKLIN RESOURCES INC	Decreased	44,249(-26.3%)	$500,457	0.0%	+43.42%	0
HSBC HOLDINGS PLC	Decreased	43,262(-19.6%)	$497,946	0.0%	+76.62%	0
Jain Global LLC	New	41,260	$466,651	0.0%	-30.60%	33
COMMONWEALTH EQUITY SERVICES, LLC	Decreased	40,000(-52.0%)	$452,400	0.0%	+16.70%	0
SEI INVESTMENTS CO	New	37,511	$424,249	0.0%	-30.60%	33
GROUP ONE TRADING LLC	Increased	34,750(+503.3%)	$393,022	0.0%	-24.59%	38
Woodline Partners LP	New	30,793	$348,269	0.0%	-30.60%	33
TWO SIGMA ADVISERS, LP	Decreased	30,500(-3.2%)	$344,955	0.0%	+62.88%	0
LMR Partners LLP	Unchanged	30,000	$339,300	0.0%	+10.85%	0
Quantinno Capital Management LP	Increased	29,264(+18.7%)	$330,976	0.0%	-13.43%	28
MetLife Investment Management, LLC	Decreased	22,714(-12.3%)	$256,895	0.0%	+28.69%	0
Creative Planning	Increased	22,104(+54.0%)	$249,996	0.0%	-8.35%	33
JPMORGAN CHASE & CO	Increased	20,789(+15.1%)	$235,124	0.0%	+69.36%	18
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	20,022(+0.1%)	$226,449	0.0%	+106.30%	23
INTECH INVESTMENT MANAGEMENT LLC	Increased	19,747(+14.5%)	$223,339	0.0%	+66.17%	26
RENAISSANCE TECHNOLOGIES LLC	Decreased	17,400(-93.0%)	$196,794	0.0%	+14.39%	0
Schonfeld Strategic Advisors LLC	Decreased	16,791(-95.4%)	$189,905	0.0%	+0.98%	0
Legal & General Group Plc	Unchanged	16,373	$185,179	0.0%	+16.27%	0
AQR CAPITAL MANAGEMENT LLC	New	15,502	$175,328	0.0%	-30.60%	31
ALLIANCEBERNSTEIN L.P.	Decreased	15,270(-79.5%)	$172,704	0.0%	+55.75%	0
Man Group plc	New	15,253	$172,511	0.0%	-30.60%	31
Vanguard Personalized Indexing Management, LLC	Decreased	13,158(-0.1%)	$148,817	0.0%	+99.84%	0
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	12,883(-7.6%)	$145,707	0.0%	+26.94%	0
Police & Firemen's Retirement System of New Jersey	Unchanged	12,843	$145,254	0.0%	+64.15%	0
BNP PARIBAS FINANCIAL MARKETS	Decreased	10,522(-26.3%)	$119,004	0.0%	+18.31%	0
ProShare Advisors LLC	New	10,259	$116,029	0.0%	-30.60%	30
ASSETMARK, INC	Decreased	8,184(-14.8%)	$92,561	0.0%	-9.23%	0
SIMPLEX TRADING, LLC	Decreased	8,014(-37.4%)	$90,638	0.0%	+10.48%	0
FMR LLC	Increased	7,691(+4.6%)	$86,985	0.0%	+31.00%	15
ROYAL BANK OF CANADA	Decreased	4,107(-99.6%)	$47,000	0.0%	-9.09%	0
NISA INVESTMENT ADVISORS, LLC	Decreased	3,602(-15.9%)	$40,739	0.0%	+47.31%	0
Russell Investments Group, Ltd.	Decreased	3,574(-74.0%)	$40,422	0.0%	+4.02%	0
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Decreased	2,651(-20.5%)	$29,983	0.0%	+26.90%	0
Mirae Asset Global Investments Co., Ltd.	New	2,630	$29,745	0.0%	-30.60%	27
Farther Finance Advisors, LLC	Decreased	2,190(-69.2%)	$24,769	0.0%	+16.53%	0
PNC FINANCIAL SERVICES GROUP, INC.	Increased	1,442(+1.8%)	$16,309	0.0%	+37.58%	13
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	New	709	$8,019	0.0%	-30.60%	25
LOS ANGELES CAPITAL MANAGEMENT LLC	New	915	$7,869	0.0%	-30.60%	25
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	New	472	$5,338	0.0%	-30.60%	23
NATIONAL BANK OF CANADA /FI/	Increased	443(+3.5%)	$5,001	0.0%	+84.35%	11
FEDERATED HERMES, INC.	Unchanged	328	$3,710	0.0%	-9.23%	0
Optiver Holding B.V.	Unchanged	322	$3,642	0.0%	-9.23%	0
COMERICA BANK	New	287	$3,246	0.0%	-30.60%	21
Rockefeller Capital Management L.P.	New	224	$2,533	0.0%	-30.60%	19
OSAIC HOLDINGS, INC.	Unchanged	90	$1,017	0.0%	+10.85%	0
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	63,760(-3.2%)	$722	0.0%	+49.20%	0
MAI Capital Management	New	10	$114	0.0%	-30.60%	17
MACQUARIE GROUP LTD	Exited	0(-100.0%)	$22,954	0.0%	+30.80%	0
JACOBS LEVY EQUITY MANAGEMENT, INC	Exited	0(-100.0%)	$644,138	0.0%	+276.74%	0
HRT FINANCIAL LP	Exited	0(-100.0%)	$1,149	0.0%	+30.80%	0
Sanctuary Advisors, LLC	Exited	0(-100.0%)	$121,017	0.0%	+30.80%	0

FULCRUM THERAPEUTICS INC

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