STRUCTURE THERAPEUTICS INC

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GPCR·86366E106·US·ADR·Healthcare - Biotechnology-13D/G

GPCR (STRUCTURE THERAPEUTICS INC) is held by 89 institutional investors as of Q2 2026. Largest holders: FMR LLC ($419.2M), WELLINGTON MANAGEMENT GROUP LLP ($396.1M), Avoro Capital Advisors LLC ($351.8M). Net institutional sentiment: Mixed.

89

Holders

(5 Elite)

$2.2B

Total Value

58% (93)

Consensus

54 buying - 39 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)76

Insider (Form 4)28

Activist (13D/13G)46

Congressional (STOCK Act)73

Holder Quality

17

★★★★★

Elite

45

★★★★

Strong

25

★★★

Solid

63

★★

Below

46

★

Weak

Held by 89 funds

5 elite

Who's Trading

Source dates: Price Aug 18, 2026 · Insiders none · Activists Aug 6, 2026 · Congress none

ActivistFMR LLC13.2%Aug 6, 2026

ActivistBVBIOTECHNOLOGY VALUE FUND L P2.6%Feb 17, 2026

ActivistDTDeep Track Capital, LP6.0%Feb 13, 2026

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Top Holders

Top Holders (89)History

AllNewIncreasedHeldDecreasedExited

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Decreased	7.8M(-7.1%)	$419.2M	0.0%	+24.69%	0
WELLINGTON MANAGEMENT GROUP LLP	Increased	7.4M(+1.6%)	$396.1M	0.1%	+13.63%	32
Avoro Capital Advisors LLC	Unchanged	6.6M	$351.8M	3.2%	+55.74%	0
MORGAN STANLEY	Increased	2.8M(+21.7%)	$150.6M	0.0%	-4.66%	36
PRINCIPAL FINANCIAL GROUP INC	Decreased	1.8M(-0.1%)	$94.1M	0.0%	+3.55%	0
AMERICAN CENTURY COMPANIES INC	Increased	1.7M(+17.0%)	$90.3M	0.0%	-2.71%	35
RTW INVESTMENTS, LP	New	1.6M	$86.3M	0.7%	-0.26%	58
DRIEHAUS CAPITAL MANAGEMENT LLC	Decreased	1.6M(-1.5%)	$83.4M	0.5%	+5.66%	0
BAKER BROS. ADVISORS LP	Unchanged	1.4M	$76.9M	0.4%	+139.02%	0
Aberdeen Group plc	Increased	639,915(+63.3%)	$34.3M	0.0%	+19.26%	42
FRANKLIN RESOURCES INC	Increased	578,839(+8.9%)	$31.1M	0.0%	+34.62%	31
BANK OF AMERICA CORP /DE/	Increased	563,422(+148.1%)	$30.2M	0.0%	-5.59%	46
ALLIANCEBERNSTEIN L.P.	Decreased	611,708(-4.2%)	$29.5M	0.0%	-19.13%	0
BlackRock, Inc.	Increased	511,149(+15.7%)	$27.4M	0.0%	+20.41%	33
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	Decreased	418,800(-10.5%)	$22.5M	0.0%	-21.02%	0
UBS Group AG	Increased	378,986(+78.0%)	$20.3M	0.0%	+33.02%	43
DEUTSCHE BANK AG\	Unchanged	331,867	$17.8M	0.0%	-21.02%	0
MWMARSHALL WACE, LLP	Increased	267,592(+287.2%)	$14.4M	0.0%	-6.60%	45
GOLDMAN SACHS GROUP INC	Decreased	242,790(-6.8%)	$13M	0.0%	+72.43%	0
AMERIPRISE FINANCIAL INC	Increased	230,514(+5.0%)	$12.4M	0.0%	+45.57%	29

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GPCRSTRUCTURE THERAPEUTICS INC

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer