IONS

Ionis Pharmaceuticals, Inc.

TickerIONS
Sector · IndustryHealthcareBiotechnology
13D/G
SecurityCommon Stock · US
CUSIP462222100

IONS institutional ownership changes in Q2 2026: 127 institutions opened or added positions, 96 trimmed or exited. IONS (Ionis Pharmaceuticals, Inc.) is held by 227 institutional investors as of Q2 2026. Top institutional shareholders: FMR LLC ($2B), Capital World Investors ($1.7B), BlackRock, Inc. ($848.8M). Institutions were buying, on balance.

227
Holders
(11 Elite)
$12.3B
Total Value
57% (223)
Consensus
127 buying96 selling
Fund holdings as of
IONS

Smart Money Verdict

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Held by 227 funds
11 elite

Who's Trading

Source dates: Price Nov 6, 2026 · Insiders Oct 19, 2026 · Activists May 15, 2026 · Congress none

InsiderSESwayze EricSell $2K
InsiderDLDevers Shannon L.Sell $59K
InsiderSESwayze EricExercise 125 sh
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Top Holders

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Action
Increased
24.6M(+0.3%)$2B0.1%-30.26%
32
Increased
21.7M(+2.3%)$1.7B0.2%-26.60%
39
Increased
10.7M(+2.5%)$848.8M0.0%-2.32%
33
Increased
7.9M(+0.7%)$623.2M0.0%-46.19%
32
Increased
7.7M(+19.7%)$606.7M0.1%-22.27%
45
Increased
7.2M(+1.3%)$571.8M0.0%-46.21%
32
Increased
6.3M(+6.7%)$495.7M0.4%-39.54%
40
Increased
6.2M(+62.6%)$490.2M0.1%-44.20%
45
Increased
4.3M(+8.5%)$343.7M0.0%-20.49%
34
Decreased
3.6M(-10.1%)$294.8M0.0%-27.58%
0
Increased
3.2M(+5.3%)$252.5M0.0%-25.03%
32
Increased
2.7M(+13.0%)$216.2M0.0%-44.24%
35
Increased
2.6M(+28.3%)$209.3M0.3%-42.37%
46
Increased
2.1M(+24.1%)$167.3M0.0%-34.79%
37
Unchanged
2M$162.4M0.8%-45.98%
0
Increased
1.9M(+17.0%)$154.4M0.1%-35.37%
35
Increased
1.6M(+3.1%)$128.7M0.0%-48.41%
31
Increased
1.6M(+1.4%)$127.3M0.0%-14.89%
31
Increased
1.6M(+453.1%)$127.1M0.0%-45.56%
49
Increased
1.6M(+11.3%)$127M0.1%+33.03%
40

Showing 1-20 of 233

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IONSIONSIonis Pharmaceuticals, Inc.

Other Healthcare stocks held by institutions

Questions investors ask about IONS

Who owns IONS?

227 institutional investors held IONS on June 30, 2026, led by FMR LLC ($2B), Capital World Investors ($1.7B) and BlackRock, Inc. ($848.8M).

How many hedge funds hold IONS?

227 institutional investors reported IONS in their 13F filings for the quarter ended June 30, 2026, $12.3B in all. 11 of them are rated Elite.

Are institutions buying or selling IONS?

Buying, on balance. In Q2 2026, 127 institutions opened or added to positions in IONS and 96 institutions trimmed or exited.

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer

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