LEXICON PHARMACEUTICALS INC

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LXRX·528872302·US·Common Stock·Healthcare - Biotechnology-Activist

LXRX (LEXICON PHARMACEUTICALS INC) is held by 89 institutional investors as of Q2 2026. Largest holders: FMR LLC ($124.3M), BlackRock, Inc. ($41.6M), VANGUARD CAPITAL MANAGEMENT LLC ($23.8M). Net institutional sentiment: Mixed.

89

Holders

(8 Elite)

$290.3M

Total Value

58% (95)

Consensus

55 buying - 40 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)46

Insider (Form 4)67

Activist (13D/13G)57

Congressional (STOCK Act)49

Holder Quality

71

★★★★★

Elite

23

★★★★

Strong

79

★★★

Solid

37

★★

Below

56

★

Weak

Held by 89 funds

8 elite

Who's Trading

Source dates: Price Oct 12, 2026 · Insiders Jun 4, 2026 · Activists Aug 6, 2026 · Congress none

ActivistFMR LLC11.7%Aug 6, 2026

InsiderBLBARKER SAM LExercise 89K shJun 3, 2026

InsiderSLSwain Judith LExercise 89K shJun 3, 2026

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Top Holders

Top Holders (89)History

AllNewIncreasedHeldDecreasedExitedFirst report

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	51.8M(+14.9%)	$124.3M	0.0%	-8.52%	35
BlackRock, Inc.	Increased	17.3M(+422.2%)	$41.6M	0.0%	-20.92%	47
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	9.9M(+4.0%)	$23.8M	0.0%	+0.58%	30
Point72 Asset Management, L.P.	Increased	8.3M(+5.6%)	$19.8M	0.0%	+0.86%	30
GEODE CAPITAL MANAGEMENT, LLC	Increased	6.2M(+97.0%)	$15M	0.0%	-31.87%	45
STATE STREET CORP	Increased	4.9M(+410.1%)	$11.8M	0.0%	-31.94%	45
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	2.4M(+331.4%)	$5.7M	0.0%	-25.57%	44
NORTHERN TRUST CORP	Increased	2M(+298.0%)	$4.7M	0.0%	-32.47%	43
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	2M(+49.2%)	$4.7M	0.0%	-29.82%	37
VFVANGUARD FIDUCIARY TRUST CO	Increased	1.6M(+22.7%)	$3.9M	0.0%	-6.04%	32
CITADEL ADVISORS LLC	Increased	1.6M(+46.2%)	$3.8M	0.0%	-3.47%	36
MILLENNIUM MANAGEMENT LLC	Decreased	1.1M(-77.1%)	$2.7M	0.0%	+42.50%	0
RENAISSANCE TECHNOLOGIES LLC	Decreased	1.1M(-29.6%)	$2.7M	0.0%	+4.84%	0
MACKENZIE FINANCIAL CORP	Increased	963,354(+24.7%)	$2.3M	0.0%	-6.59%	32
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	696,776(-67.2%)	$1.7M	0.0%	+34.22%	0
UBS Group AG	Decreased	684,713(-72.4%)	$1.6M	0.0%	+50.25%	0
TWO SIGMA INVESTMENTS, LP	Decreased	643,444(-46.4%)	$1.5M	0.0%	+28.35%	0
Nuveen, LLC	New	586,664	$1.4M	0.0%	-31.25%	35
Bank of New York Mellon Corp	Increased	568,706(+1971.1%)	$1.4M	0.0%	-31.40%	41
Invesco Ltd.	Decreased	508,071(-0.8%)	$1.2M	0.0%	+58.55%	0

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer