ORCHESTRA BIOMED HLDGS INC

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OBIO·68572M106·US·equity·Healthcare - Biotechnology-Activist

OBIO (ORCHESTRA BIOMED HLDGS INC) is held by 36 institutional investors as of Q1 2026. Largest holders: RTW INVESTMENTS, LP ($35.3M), Alyeska Investment Group, L.P. ($4.3M), MILLENNIUM MANAGEMENT LLC ($3M). Net institutional sentiment: Mixed.

36

Holders

Avg rating(5 Elite)

$55.3M

Total Value

49% (49)

Fund Consensus

22 buying - 23 selling

Smart Money Verdict

View all

62Mixed MomentumStrong Convergence

Institutional (13F)52

Insider (Form 4)82

Activist (13D/13G)54

Congressional (STOCK Act)

No data

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See how OBIO's score breaks down across 4 SEC sources

Holder Quality

5

★★★★★

Elite

10

★★★★

Strong

15

★★★

Solid

14

★★

Below

5

★

Weak

Held by 36 funds

5 elite

Who's Trading

InsiderAJAryeh JasonBuy $2KMay 18, 2026

InsiderHPHochman David PBuy $19KMay 15, 2026

InsiderAJAryeh JasonBuy $35KMay 15, 2026

InsiderFSFain Eric SBuy $83KMay 14, 2026

ActivistRTW Investments, LP19.2%Apr 29, 2026

ActivistMPMedtronic plc17.8%Feb 27, 2026

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13F: Mar 31, 2026Insider & Congress: Updated regularly

Positions (36)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RTW INVESTMENTS, LP	Unchanged	8.3M	$35.3M	0.4%	-67.91%	0
AIAlyeska Investment Group, L.P.	Unchanged	1M	$4.3M	0.0%	+51.22%	0
MILLENNIUM MANAGEMENT LLC	Increased	702,543(+188.6%)	$3M	0.0%	-2.42%	43
BlackRock, Inc.	Increased	635,714(+0.8%)	$2.7M	0.0%	-12.49%	18
GEODE CAPITAL MANAGEMENT, LLC	Increased	485,492(+2.6%)	$2.1M	0.0%	-48.43%	27
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	265,499(+0.7%)	$1.1M	0.0%	-48.00%	25
MWMARSHALL WACE, LLP	Increased	188,484(+9.8%)	$801,059	0.0%	-10.57%	27
STATE STREET CORP	Increased	169,410(+6.5%)	$719,993	0.0%	-42.37%	18
GOLDMAN SACHS GROUP INC	Increased	155,242(+15.8%)	$659,779	0.0%	-8.73%	28
NORTHERN TRUST CORP	Increased	118,274(+6.7%)	$502,665	0.0%	-47.95%	26
Qube Research & Technologies Ltd	Increased	108,953(+2.1%)	$463,050	0.0%	-0.66%	24
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	97,521(-37.1%)	$414,464	0.0%	+4.63%	0
Point72 Asset Management, L.P.	Decreased	87,888(-45.7%)	$373,524	0.0%	-10.14%	0
CITADEL ADVISORS LLC	Increased	79,185(+162.4%)	$336,536	0.0%	-7.82%	38
Hudson Bay Capital Management LP	Increased	71,134(+43.9%)	$302,320	0.0%	-11.58%	32
RENAISSANCE TECHNOLOGIES LLC	Decreased	70,900(-53.1%)	$301,325	0.0%	+42.94%	0
TWO SIGMA INVESTMENTS, LP	Decreased	60,107(-30.6%)	$255,455	0.0%	-10.14%	0
BARCLAYS PLC	Decreased	59,342(-37.2%)	$252,204	0.0%	-10.14%	0
JANE STREET GROUP, LLC	Decreased	55,680(-68.0%)	$236,640	0.0%	+5.07%	0
BANK OF AMERICA CORP /DE/	Increased	52,761(+200.7%)	$224,234	0.0%	-8.19%	25

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High Conviction Moves-Signal Convergence-Fund Consensus-Double-Down Signals

Data sourced from four SEC data sources: 13F, Form 4, 13D/13G, and STOCK Act. Not financial advice. Full disclaimer