OMEROS CORP (OMER) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling OMER?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for OMEROS CORP, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on OMER?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for OMEROS CORP.

Is institutional money flowing into OMER?

88 institutional investors hold OMEROS CORP (OMER). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about OMER?

Track institutional sentiment and conviction scores for OMEROS CORP (OMER) including Smart Money Verdict and position changes on HoldingsIntel.

OMEROS CORP

OMER·682143102·US·equity·Healthcare - Biotechnology-13D/G

OMER (OMEROS CORP) is held by 88 institutional investors as of Q4 2025. Largest holders: BlackRock, Inc. ($86.9M), VANGUARD GROUP INC ($68.9M), UBS Group AG ($38.2M). Net institutional sentiment: Bullish.

Holders

Avg rating(7 Elite)

$458.5M

Total Value

68% (95)

Fund Consensus

61 buying - 28 selling

Smart Money Verdict- Q4 2025View all

57Mixed MomentumSplit Signals

Held by 88 funds

7 elite

Who's Trading

ActivistThe Vanguard Group0.0%Mar 27, 2026

Activist

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	5.1M(+13.7%)	$86.9M	0.0%	+14.68%	34
VANGUARD GROUP INC	Increased	4M(+19.9%)	$68.9M	0.0%	+88.07%	35
UBS Group AG	Increased	2.2M(+213.5%)	$38.2M	0.0%	-18.96%	47
STIFEL FINANCIAL CORP	Decreased	1.8M(-0.1%)	$31.1M	0.0%	+46.00%	0
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.6M(+6.3%)	$28M	0.0%	+38.49%	31
STATE STREET CORP	Increased	1.6M(+26.9%)	$27M	0.0%	+75.71%	36
D. E. Shaw & Co., Inc.	Decreased	754,999(-24.9%)	$13M	0.0%	+29.12%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	741,895(+570.9%)	$12.7M	0.0%	-25.74%	45
Corient Private Wealth LLC	Increased	687,325(+12.9%)	$11.8M	0.0%	+155.86%	31
NOMURA HOLDINGS INC	Increased	655,021(+1399.6%)	$11.2M	0.0%	-29.13%	45
BANK OF MONTREAL /CAN/	Increased	601,643(+6.8%)	$10.3M	0.0%	+15.06%	30
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	593,222(+7.2%)	$10.2M	0.0%	+41.79%	30
NORTHERN TRUST CORP	Decreased	526,732(-1.7%)	$9M	0.0%	+49.12%	0
TWO SIGMA INVESTMENTS, LP	Decreased	524,757(-43.8%)	$9M	0.0%	+223.53%	0
ROYAL BANK OF CANADA	Decreased	498,399(-8.3%)	$8.6M	0.0%	+25.46%	0
JANE STREET GROUP, LLC	Increased	463,622(+64.9%)	$8M	0.0%	+18.83%	40
MILLENNIUM MANAGEMENT LLC	Increased	441,811(+9.9%)	$7.6M	0.0%	+55.49%	30
MORGAN STANLEY	Decreased	386,152(-80.6%)	$6.6M	0.0%	+138.44%	0
CITADEL ADVISORS LLC	Decreased	240,352(-38.9%)	$4.1M	0.0%	+115.62%	0
GOLDMAN SACHS GROUP INC	Decreased	227,294(-32.4%)	$3.9M	0.0%	+67.13%	0
WELLINGTON MANAGEMENT GROUP LLP	Increased	202,617(+4.2%)	$3.5M	0.0%	+56.40%	28
Bank of New York Mellon Corp	Increased	165,782(+2.1%)	$2.8M	0.0%	+87.82%	27
WELLS FARGO & COMPANY/MN	Increased	165,280(+23.3%)	$2.8M	0.0%	+79.46%	32
Invesco Ltd.	Increased	154,782(+26.8%)	$2.7M	0.0%	+42.08%	32
Nuveen, LLC	Increased	153,187(+74.8%)	$2.6M	0.0%	-3.83%	40
GROUP ONE TRADING LLC	Increased	133,269(+35.6%)	$2.3M	0.0%	+50.32%	34
SIMPLEX TRADING, LLC	Increased	123,979(+458.0%)	$2.1M	0.0%	-20.65%	42
BARCLAYS PLC	Decreased	120,490(-8.7%)	$2.1M	0.0%	+200.07%	0
AMERIPRISE FINANCIAL INC	Increased	117,004(+0.4%)	$2M	0.0%	+241.85%	26
BANK OF AMERICA CORP /DE/	Decreased	114,808(-58.3%)	$2M	0.0%	+95.59%	0
Walleye Capital LLC	Increased	109,956(+636.8%)	$1.9M	0.0%	-23.45%	42
HighTower Advisors, LLC	Increased	104,059(+9.3%)	$1.8M	0.0%	+56.29%	28
RHUMBLINE ADVISERS	Decreased	100,105(-5.5%)	$1.7M	0.0%	+138.51%	0
DIMENSIONAL FUND ADVISORS LP	New	96,948	$1.7M	0.0%	-31.37%	36
MML INVESTORS SERVICES, LLC	Increased	77,875(+31.6%)	$1.3M	0.0%	+50.23%	32
TWO SIGMA ADVISERS, LP	Decreased	76,100(-86.8%)	$1.3M	0.0%	+233.09%	0
ALLIANCEBERNSTEIN L.P.	Increased	73,490(+8.7%)	$1.3M	0.0%	+55.48%	28
Walleye Trading LLC	Increased	69,653(+409.4%)	$1.2M	0.0%	-19.45%	41
Brevan Howard Capital Management LP	Decreased	64,957(-49.8%)	$1.1M	0.0%	+244.12%	0
Verition Fund Management LLC	New	63,493	$1.1M	0.0%	-31.37%	35
DEUTSCHE BANK AG\	Increased	48,694(+19.3%)	$836,563	0.0%	+14.68%	29
COMERICA BANK	Increased	38,000(+8.6%)	$652,650	0.0%	+133.01%	27
JPMORGAN CHASE & CO	Decreased	37,191(-91.1%)	$638,755	0.0%	+153.19%	0
MetLife Investment Management, LLC	Increased	36,200(+76.5%)	$621,735	0.0%	+15.43%	37
SEI INVESTMENTS CO	Increased	31,766(+142.2%)	$545,577	0.0%	-12.07%	39
Focus Partners Wealth	New	31,034	$533,009	0.0%	-31.37%	34
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	30,585(+1.3%)	$525,297	0.0%	+153.08%	24
Cerity Partners LLC	Increased	30,450(+6.1%)	$522,979	0.0%	+146.54%	26
INTECH INVESTMENT MANAGEMENT LLC	Increased	29,967(+16.9%)	$514,683	0.0%	+24.54%	28
CITIGROUP INC	Increased	27,489(+398.3%)	$472,124	0.0%	-24.81%	39
Man Group plc	New	27,099	$465,425	0.0%	-31.37%	33
Quantinno Capital Management LP	Increased	25,074(+37.7%)	$430,646	0.0%	+51.57%	31
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	Increased	31,728(+9.0%)	$429,280	0.0%	+32.63%	26
FARALLON CAPITAL MANAGEMENT LLC	New	23,000	$395,025	0.0%	-31.37%	33
AQR CAPITAL MANAGEMENT LLC	Increased	22,838(+7.2%)	$392,243	0.0%	+84.68%	26
CANADA PENSION PLAN INVESTMENT BOARD	New	21,700	$372,698	0.0%	-31.37%	33
NEW YORK STATE COMMON RETIREMENT FUND	Increased	20,713(+81.5%)	$355,746	0.0%	-5.09%	36
Engineers Gate Manager LP	New	20,082	$344,908	0.0%	-31.37%	33
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	19,850(-0.2%)	$340,924	0.0%	+121.60%	0
FMR LLC	Increased	18,068(+37.0%)	$310,325	0.0%	+3.81%	21
Creative Planning	New	16,916	$290,533	0.0%	-31.37%	32
Police & Firemen's Retirement System of New Jersey	Unchanged	16,360	$280,983	0.0%	+42.58%	0
BNP PARIBAS FINANCIAL MARKETS	Decreased	16,351(-81.4%)	$280,828	0.0%	+196.67%	0
ProShare Advisors LLC	Increased	15,171(+12.1%)	$260,561	0.0%	+54.13%	26
Russell Investments Group, Ltd.	Increased	14,014(+31.0%)	$240,690	0.0%	+60.75%	29
LOS ANGELES CAPITAL MANAGEMENT LLC	New	30,920	$232,518	0.0%	-31.37%	32
Schonfeld Strategic Advisors LLC	New	12,667	$217,554	0.0%	-31.37%	32
RAYMOND JAMES FINANCIAL INC	New	12,242	$210,256	0.0%	-31.37%	32
Rafferty Asset Management, LLC	New	12,226	$209,982	0.0%	-31.37%	32
VOYA INVESTMENT MANAGEMENT LLC	Increased	11,405(+1.9%)	$195,881	0.0%	+111.70%	23
OSAIC HOLDINGS, INC.	Increased	7,547(+34.5%)	$129,655	0.0%	+10.98%	29
Farther Finance Advisors, LLC	Increased	7,106(+16.4%)	$122,046	0.0%	+76.43%	26
Legal & General Group Plc	Decreased	6,971(-1.6%)	$119,727	0.0%	+134.61%	0
Vontobel Holding Ltd.	New	5,450	$93,604	0.0%	-31.37%	30
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Decreased	4,055(-0.0%)	$69,645	0.0%	+119.24%	0
Optiver Holding B.V.	Increased	3,747(+596.5%)	$64,355	0.0%	-23.04%	23
Mirae Asset Global Investments Co., Ltd.	Increased	3,445(+30.9%)	$59,168	0.0%	+13.74%	26
NewEdge Advisors, LLC	New	1,000	$17,175	0.0%	-31.37%	25
FIFTH THIRD BANCORP	Unchanged	1,000	$17,175	0.0%	-16.66%	0
NISA INVESTMENT ADVISORS, LLC	Decreased	804(-52.0%)	$13,809	0.0%	+80.25%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Decreased	765(-23.5%)	$13,139	0.0%	+37.43%	0
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	Unchanged	500	$8,588	0.0%	+178.47%	0
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	377(-44.1%)	$6,475	0.0%	+224.68%	0
Federation des caisses Desjardins du Quebec	Unchanged	300	$5,153	0.0%	-34.46%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	New	231	$3,967	0.0%	-31.37%	22
Rockefeller Capital Management L.P.	New	195	$3,349	0.0%	-31.37%	21
PRICE T ROWE ASSOCIATES INC /MD/	Increased	95,745(+6.9%)	$1,644	0.0%	+80.24%	12
Allworth Financial LP	Decreased	44(-22.8%)	$756	0.0%	+178.47%	0
MARSHALL WACE, LLP	Exited	0(-100.0%)	$1.9M	0.0%	+115.92%	0
STATE OF WISCONSIN INVESTMENT BOARD	Exited	0(-100.0%)	$138,080	0.0%	+305.74%	0
US BANCORP \DE\	Exited	0(-100.0%)	$205	0.0%	+293.34%	0
RENAISSANCE TECHNOLOGIES LLC	Exited	0(-100.0%)	$1.4M	0.0%	+430.00%	0
Squarepoint Ops LLC	Exited	0(-100.0%)	$637,534	0.0%	+354.32%	0
MAI Capital Management	Exited	0(-100.0%)	$5,613	0.0%	+74.13%	0
Quadrature Capital Ltd	Exited	0(-100.0%)	$88,178	0.0%	+305.74%	0

OMEROS CORP

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