PRAXIS PRECISION MEDICINES I

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PRAX·74006W207·US·Common Stock·Healthcare - Biotechnology-13D/G

PRAX (PRAXIS PRECISION MEDICINES I) is held by 162 institutional investors as of Q2 2026. Largest holders: FMR LLC ($775.7M), BlackRock, Inc. ($767.5M), BAKER BROS. ADVISORS LP ($587M). Net institutional sentiment: Mixed.

162

Holders

(11 Elite)

$7.7B

Total Value

62% (165)

Consensus

102 buying - 63 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)81

Insider (Form 4)49

Activist (13D/13G)80

Congressional (STOCK Act)68

Holder Quality

32

★★★★★

Elite

14

★★★★

Strong

40

★★★

Solid

78

★★

Below

79

★

Weak

Held by 162 funds

11 elite

Who's Trading

Source dates: Price Aug 28, 2026 · Insiders Jun 26, 2026 · Activists Aug 14, 2026 · Congress none

ActivistOIORBIS INVESTMENT MANAGEMENT LTD5.5%Aug 14, 2026

InsiderDJDeSimone JillSell $98KJun 24, 2026

InsiderDJDeSimone JillSell $158KJun 24, 2026

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Top Holders

Top Holders (162)History

AllNewIncreasedHeldDecreasedExited

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	2.3M(+7.2%)	$775.7M	0.0%	+13.89%	34
BlackRock, Inc.	Decreased	2.3M(-1.4%)	$767.5M	0.0%	+178.92%	0
BAKER BROS. ADVISORS LP	Unchanged	1.8M	$587M	2.9%	+67.45%	0
Orbis Allan Gray Ltd	Decreased	1.5M(-38.1%)	$512.2M	1.8%	+12.13%	0
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	1.3M(+76.4%)	$447M	0.0%	+5.95%	47
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	1.2M(+1.1%)	$413.6M	0.0%	+8.28%	31
STATE STREET CORP	Increased	1M(+16.1%)	$343.7M	0.0%	+308.05%	36
AGADAGE CAPITAL PARTNERS GP, L.L.C.	Increased	1M(+24.5%)	$340M	0.5%	+232.67%	45
DRIEHAUS CAPITAL MANAGEMENT LLC	Increased	959,048(+1.0%)	$321.1M	1.9%	+106.74%	49
MORGAN STANLEY	Increased	854,112(+2.5%)	$285.9M	0.0%	+147.65%	32
GEODE CAPITAL MANAGEMENT, LLC	Increased	748,039(+14.9%)	$250.5M	0.0%	+113.82%	35
GOLDMAN SACHS GROUP INC	Decreased	548,830(-22.8%)	$183.7M	0.0%	+245.71%	0
BANK OF AMERICA CORP /DE/	Increased	546,930(+2.3%)	$183.1M	0.0%	+383.20%	31
Invesco Ltd.	Increased	537,548(+775.5%)	$180M	0.0%	+6.75%	49
Hood River Capital Management LLC	Increased	425,167(+18.6%)	$142.3M	1.0%	+12.52%	56
FRANKLIN RESOURCES INC	Increased	327,124(+18.5%)	$109.5M	0.0%	+180.41%	35
Pictet Asset Management Holding SA	Increased	291,689(+1.8%)	$98M	0.1%	+14.53%	30
Polar Capital Holdings Plc	New	279,131	$93.5M	0.2%	+2.97%	49
NORTHERN TRUST CORP	Increased	240,887(+5.7%)	$80.6M	0.0%	+147.88%	31
AMERICAN CENTURY COMPANIES INC	Increased	237,315(+85.0%)	$79.5M	0.0%	+13.64%	46

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer