PRIME MEDICINE INC

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PRME·74168J101·US·equity·Healthcare - Biotechnology-Activist

PRME (PRIME MEDICINE INC) is held by 108 institutional investors as of Q1 2026. Largest holders: Alphabet Inc. ($57.6M), BlackRock, Inc. ($29.6M), STATE STREET CORP ($22.1M). Net institutional sentiment: Mixed.

108

Holders

Avg rating(10 Elite)

$262M

Total Value

53% (121)

Fund Consensus

60 buying - 53 selling

Smart Money Verdict

View all

66Positive MomentumStrong Convergence

Institutional (13F)50

Insider (Form 4)100

Activist (13D/13G)50

Congressional (STOCK Act)

No data

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See how PRME's score breaks down across 4 SEC sources

Holder Quality

10

★★★★★

Elite

36

★★★★

Strong

39

★★★

Solid

30

★★

Below

6

★

Weak

Held by 108 funds

10 elite

Who's Trading

ActivistTRT. Rowe Price Investment Management, Inc.3.3%Feb 17, 2026

ActivistG2GV 2019, L.P.7.5%Nov 12, 2025

InsiderGLGV 2021 GP, L.L.C.Buy $5.0MAug 1, 2025

InsiderALARCH Venture Partners X, LLCBuy $10.0MAug 1, 2025

InsiderALARCH Venture Partners XII, LLCBuy $10.0MAug 1, 2025

InsiderNRNELSEN ROBERTBuy $10.0MAug 1, 2025

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13F: Mar 31, 2026Insider & Congress: Updated regularly

Positions (108)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
ALAlphabet Inc.	Unchanged	16.6M	$57.6M	1.4%	-80.65%	0
BlackRock, Inc.	Increased	8.5M(+2.8%)	$29.6M	0.0%	-12.89%	30
STATE STREET CORP	Increased	6.3M(+24.5%)	$22.1M	0.0%	-32.45%	35
ARK Investment Management LLC	Increased	6.2M(+16.4%)	$21.7M	0.2%	-59.93%	39
BALYASNY ASSET MANAGEMENT L.P.	Increased	4.1M(+32.0%)	$14.3M	0.0%	-19.80%	36
Woodline Partners LP	Increased	3M(+0.0%)	$10.5M	0.0%	-44.92%	28
Sumitomo Mitsui Trust Group, Inc.	Decreased	2.9M(-9.4%)	$10.2M	0.0%	-68.16%	0
Amova Asset Management Americas, Inc.	Decreased	2.9M(-9.4%)	$10.2M	0.1%	-68.11%	0
UBS Group AG	Increased	2.9M(+18.4%)	$10.1M	0.0%	-19.13%	33
GEODE CAPITAL MANAGEMENT, LLC	Increased	2.7M(+4.4%)	$9.6M	0.0%	-59.02%	29
FMR LLC	Decreased	1.8M(-18.7%)	$6.2M	0.0%	+5.40%	0
TWO SIGMA INVESTMENTS, LP	Decreased	1.6M(-3.5%)	$5.5M	0.0%	-26.28%	0
DED. E. Shaw & Co., Inc.	Decreased	1.4M(-10.2%)	$4.8M	0.0%	-44.92%	0
FARALLON CAPITAL MANAGEMENT LLC	Unchanged	1.2M	$4.3M	0.0%	-47.54%	0
GOLDMAN SACHS GROUP INC	Decreased	970,425(-44.7%)	$3.4M	0.0%	-18.16%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	917,212(-2.1%)	$3.2M	0.0%	-55.99%	0
NORTHERN TRUST CORP	Increased	886,716(+5.3%)	$3.1M	0.0%	-62.59%	28
JPMORGAN CHASE & CO	Increased	844,154(+93.7%)	$2.7M	0.0%	-23.29%	42
RENAISSANCE TECHNOLOGIES LLC	Decreased	741,039(-35.5%)	$2.6M	0.0%	-36.97%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	715,829(-39.2%)	$2.5M	0.0%	-9.81%	0

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High Conviction Moves-Signal Convergence-Fund Consensus-Double-Down Signals

Data sourced from four SEC data sources: 13F, Form 4, 13D/13G, and STOCK Act. Not financial advice. Full disclaimer