RELAY THERAPEUTICS INC (RLAY) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

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What is the Smart Money Verdict on RLAY?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for RELAY THERAPEUTICS INC.

Is institutional money flowing into RLAY?

120 institutional investors hold RELAY THERAPEUTICS INC (RLAY). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about RLAY?

Track institutional sentiment and conviction scores for RELAY THERAPEUTICS INC (RLAY) including Smart Money Verdict and position changes on HoldingsIntel.

RELAY THERAPEUTICS INC

RLAY·75943R102·US·equity·Healthcare - Biotechnology-13D/G

RLAY (RELAY THERAPEUTICS INC) is held by 120 institutional investors as of Q4 2025. Largest holders: SB INVESTMENT ADVISERS (UK) LTD ($236.1M), Point72 Asset Management, L.P. ($117.2M), BlackRock, Inc. ($111.9M). Net institutional sentiment: Mixed.

120

Holders

Avg rating(8 Elite)

$906.5M

Total Value

63% (129)

Fund Consensus

70 buying - 42 selling

Smart Money VerdictView all

48Weak MomentumSplit Signals

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See how RLAY's score breaks down across 4 SEC sources

Held by 120 funds

8 elite

Who's Trading

ActivistPerceptive Advisors LLC10.0%Apr 13, 2026

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
SB INVESTMENT ADVISERS (UK) LTD	Unchanged	27.9M	$236.1M	2.4%	-75.36%	0
Point72 Asset Management, L.P.	Decreased	13.9M(-6.2%)	$117.2M	0.1%	+181.28%	0
BlackRock, Inc.	Decreased	13.2M(-3.9%)	$111.9M	0.0%	+135.65%	0
VANGUARD GROUP INC	Increased	9.7M(+3.1%)	$82M	0.0%	+33.76%	31
STATE STREET CORP	Increased	6.4M(+26.9%)	$54.4M	0.0%	+8.70%	36
GEODE CAPITAL MANAGEMENT, LLC	Increased	3.4M(+11.6%)	$28.8M	0.0%	-48.51%	32
DIMENSIONAL FUND ADVISORS LP	Decreased	2.5M(-0.1%)	$21M	0.0%	+5.66%	0
BALYASNY ASSET MANAGEMENT L.P.	Increased	2.1M(+78.7%)	$17.8M	0.0%	+49.65%	43
MORGAN STANLEY	Increased	2M(+14.4%)	$17.1M	0.0%	+73.31%	32
GOLDMAN SACHS GROUP INC	Decreased	1.9M(-0.5%)	$15.7M	0.0%	+135.65%	0
TWO SIGMA INVESTMENTS, LP	Increased	1.6M(+42.4%)	$13.2M	0.0%	+35.47%	38
TWO SIGMA ADVISERS, LP	Increased	1.3M(+14.7%)	$10.9M	0.0%	+56.88%	32
AQR CAPITAL MANAGEMENT LLC	Decreased	1.2M(-10.6%)	$9.8M	0.0%	+154.08%	0
BAKER BROS. ADVISORS LP	Unchanged	1.2M	$9.8M	0.1%	-27.37%	0
ExodusPoint Capital Management, LP	New	1.1M	$9.7M	0.1%	+17.96%	38
NORTHERN TRUST CORP	Decreased	1.1M(-2.3%)	$9.6M	0.0%	-56.79%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	1.1M(+2.3%)	$9.6M	0.0%	-51.88%	28
BANK OF AMERICA CORP /DE/	Decreased	1M(-12.9%)	$8.8M	0.0%	+176.51%	0
MILLENNIUM MANAGEMENT LLC	Increased	896,909(+20.6%)	$7.6M	0.0%	+71.02%	33
Invesco Ltd.	Increased	865,481(+139.6%)	$7.3M	0.0%	+14.43%	44
Woodline Partners LP	Decreased	679,115(-33.3%)	$5.7M	0.0%	+15.35%	0
RENAISSANCE TECHNOLOGIES LLC	Decreased	647,899(-36.7%)	$5.5M	0.0%	+96.73%	0
Allianz Asset Management GmbH	New	560,298	$4.7M	0.0%	+17.96%	37
ADAGE CAPITAL PARTNERS GP, L.L.C.	New	500,000	$4.2M	0.0%	+17.96%	37
Trexquant Investment LP	New	472,045	$4M	0.0%	+17.96%	37
Hudson Bay Capital Management LP	New	451,500	$3.8M	0.0%	+17.96%	37
AMERICAN CENTURY COMPANIES INC	Increased	432,493(+9.8%)	$3.7M	0.0%	-1.78%	29
JPMORGAN CHASE & CO	Decreased	425,958(-7.9%)	$3.6M	0.0%	+135.65%	0
CONGRESS ASSET MANAGEMENT CO	Increased	414,167(+1.3%)	$3.5M	0.0%	+25.58%	27
BARCLAYS PLC	Decreased	414,143(-10.3%)	$3.5M	0.0%	+41.88%	0
Connor, Clark & Lunn Investment Management Ltd.	New	389,563	$3.3M	0.0%	+17.96%	37
Bank of New York Mellon Corp	Increased	378,703(+1.9%)	$3.2M	0.0%	-56.52%	27
Nuveen, LLC	Increased	300,464(+4.2%)	$2.5M	0.0%	+234.45%	27
UBS Group AG	Increased	296,017(+94.4%)	$2.5M	0.0%	+20.53%	42
RAYMOND JAMES FINANCIAL INC	Increased	259,411(+20.8%)	$2.2M	0.0%	+98.14%	31
Swiss National Bank	Increased	238,000(+2.3%)	$2M	0.0%	-54.89%	26
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	222,929(+62.9%)	$1.9M	0.0%	+73.97%	37
RHUMBLINE ADVISERS	Decreased	215,741(-0.8%)	$1.8M	0.0%	-47.73%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	209,848(+3.8%)	$1.8M	0.0%	-39.23%	27
Rafferty Asset Management, LLC	Increased	193,756(+27.8%)	$1.6M	0.0%	-16.49%	32
OSAIC HOLDINGS, INC.	Unchanged	186,388	$1.6M	0.0%	+88.89%	0
TD ASSET MANAGEMENT INC	Increased	181,988(+53.9%)	$1.5M	0.0%	-18.60%	36
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Increased	177,486(+9.3%)	$1.5M	0.0%	-48.91%	28
IEQ CAPITAL, LLC	Decreased	162,285(-17.4%)	$1.4M	0.0%	+198.62%	0
FMR LLC	Decreased	162,222(-0.3%)	$1.4M	0.0%	+174.71%	0
WELLS FARGO & COMPANY/MN	Increased	157,892(+55.5%)	$1.3M	0.0%	+36.01%	36
XTX Topco Ltd	New	157,406	$1.3M	0.0%	+17.96%	35
ALLIANCEBERNSTEIN L.P.	Unchanged	145,251	$1.2M	0.0%	-12.95%	0
ALPS ADVISORS INC	Increased	142,321(+72.7%)	$1.2M	0.0%	+81.56%	38
Sanctuary Advisors, LLC	New	142,228	$1.2M	0.0%	+17.96%	35
DEUTSCHE BANK AG\	Increased	123,994(+3.2%)	$1M	0.0%	+5.81%	26
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Decreased	117,677(-15.1%)	$995,547	0.0%	-50.88%	0
CITADEL ADVISORS LLC	New	114,143	$965,649	0.0%	+17.96%	35
NEOS Investment Management LLC	Increased	113,230(+21.1%)	$957,926	0.0%	+49.55%	30
Legal & General Group Plc	Decreased	109,208(-2.8%)	$923,900	0.0%	-48.19%	0
STATE OF WISCONSIN INVESTMENT BOARD	Increased	101,160(+24.3%)	$855,814	0.0%	+69.60%	30
Squarepoint Ops LLC	New	94,210	$797,017	0.0%	+17.96%	34
Man Group plc	Decreased	87,037(-53.7%)	$736,333	0.0%	+162.71%	0
Creative Planning	Increased	85,836(+7.5%)	$726,173	0.0%	+143.35%	27
TUDOR INVESTMENT CORP ET AL	Increased	84,163(+10.1%)	$712,019	0.0%	+79.75%	27
Engineers Gate Manager LP	New	78,368	$662,993	0.0%	+17.96%	34
MetLife Investment Management, LLC	Increased	77,536(+22.6%)	$655,955	0.0%	-43.41%	30
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	76,679(+9.5%)	$647,461	0.0%	+61.78%	27
JANE STREET GROUP, LLC	Decreased	76,476(-58.6%)	$646,987	0.0%	+89.79%	0
Jain Global LLC	New	66,587	$563,326	0.0%	+17.96%	34
Allspring Global Investments Holdings, LLC	Increased	65,447(+9.6%)	$535,356	0.0%	+71.65%	27
Schonfeld Strategic Advisors LLC	New	61,853	$523,276	0.0%	+17.96%	33
Zurcher Kantonalbank (Zurich Cantonalbank)	Increased	57,234(+20.2%)	$484,200	0.0%	-8.06%	29
BANK OF MONTREAL /CAN/	Unchanged	56,454	$477,601	0.0%	+226.55%	0
INTECH INVESTMENT MANAGEMENT LLC	Increased	53,201(+37.4%)	$450,080	0.0%	+65.95%	31
FRANKLIN RESOURCES INC	Decreased	48,915(-87.1%)	$413,821	0.0%	+161.53%	0
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	Increased	47,644(+1.1%)	$389,251	0.0%	+188.95%	24
NEW YORK STATE COMMON RETIREMENT FUND	Increased	45,799(+55.8%)	$387,460	0.0%	-32.57%	34
CANADA PENSION PLAN INVESTMENT BOARD	New	42,000	$355,320	0.0%	+17.96%	33
LOS ANGELES CAPITAL MANAGEMENT LLC	Decreased	47,982(-21.6%)	$352,188	0.0%	+86.49%	0
Cresset Asset Management, LLC	Decreased	37,084(-4.8%)	$313,731	0.0%	+233.67%	0
Police & Firemen's Retirement System of New Jersey	Unchanged	37,005	$313,062	0.0%	+140.65%	0
JANUS HENDERSON GROUP PLC	Unchanged	36,873	$312,499	0.0%	-38.55%	0
CAPTRUST FINANCIAL ADVISORS	Increased	35,566(+41.0%)	$300,888	0.0%	+83.81%	31
LPL Financial LLC	Decreased	34,144(-18.6%)	$288,858	0.0%	+65.31%	0
Arizona State Retirement System	Decreased	33,531(-5.4%)	$283,672	0.0%	-49.26%	0
ProShare Advisors LLC	Increased	33,391(+16.0%)	$282,487	0.0%	-36.14%	27
CITIGROUP INC	Increased	30,930(+116.1%)	$261,668	0.0%	+56.89%	37
GROUP ONE TRADING LLC	Increased	28,952(+148.1%)	$244,934	0.0%	+41.51%	37
Vanguard Personalized Indexing Management, LLC	Decreased	27,587(-1.0%)	$233,386	0.0%	+154.08%	0
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	25,807	$218,327	0.0%	-64.17%	0
SEI INVESTMENTS CO	Unchanged	25,630	$216,830	0.0%	+262.13%	0
KLP KAPITALFORVALTNING AS	Unchanged	24,700	$208,962	0.0%	+135.65%	0
VOYA INVESTMENT MANAGEMENT LLC	Unchanged	24,575	$207,905	0.0%	+47.75%	0
Erste Asset Management GmbH	Unchanged	23,100	$194,271	0.0%	-77.59%	0
Cerity Partners LLC	Decreased	21,046(-0.9%)	$178,049	0.0%	+154.51%	0
Merit Financial Group, LLC	Decreased	20,485(-0.1%)	$173,302	0.0%	+198.30%	0
BNP PARIBAS FINANCIAL MARKETS	Decreased	20,004(-38.0%)	$169,234	0.0%	+161.86%	0
TEACHER RETIREMENT SYSTEM OF TEXAS	Decreased	17,473(-39.5%)	$147,821	0.0%	-40.60%	0
Focus Partners Wealth	New	17,333	$146,637	0.0%	+17.96%	31
Quantinno Capital Management LP	Increased	17,277(+39.6%)	$146,163	0.0%	+61.82%	30
Pictet Asset Management Holding SA	New	15,052	$127,340	0.0%	+17.96%	31
VICTORY CAPITAL MANAGEMENT INC	Increased	15,016(+0.2%)	$127,035	0.0%	+16.36%	22
VIRGINIA RETIREMENT SYSTEMS ET Al	New	12,900	$109,134	0.0%	+17.96%	30
MERCER GLOBAL ADVISORS INC /ADV	Decreased	12,838(-1.7%)	$108,609	0.0%	+89.79%	0
EP Wealth Advisors, LLC	New	12,502	$105,767	0.0%	+17.96%	30
Russell Investments Group, Ltd.	Increased	12,462(+0.2%)	$105,428	0.0%	+96.69%	22
XPONANCE LLC	Increased	11,002(+6.4%)	$93,077	0.0%	+172.36%	23
Steward Partners Investment Advisory, LLC	Increased	8,900(+9.9%)	$75,294	0.0%	+17.53%	23
Mirae Asset Global Investments Co., Ltd.	Increased	8,422(+26.4%)	$71,250	0.0%	-11.15%	26
US BANCORP \DE\	Unchanged	5,131	$43,408	0.0%	+151.63%	0
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	4,606(-1.0%)	$38,967	0.0%	+160.19%	0
Farther Finance Advisors, LLC	Increased	4,140(+17.3%)	$35,024	0.0%	+141.20%	23
ROYAL BANK OF CANADA	Decreased	4,060(-98.2%)	$35,000	0.0%	+196.30%	0
NISA INVESTMENT ADVISORS, LLC	Unchanged	2,074	$17,546	0.0%	+85.64%	0
PRICE T ROWE ASSOCIATES INC /MD/	Increased	1.6M(+44.6%)	$13,921	0.0%	-18.67%	24
Allworth Financial LP	Decreased	1,334(-7.0%)	$11,286	0.0%	+110.31%	0
CIBC Private Wealth Group LLC	New	680	$5,753	0.0%	+17.96%	24
COMERICA BANK	Unchanged	664	$5,617	0.0%	+252.16%	0
Rockefeller Capital Management L.P.	New	454	$3,841	0.0%	+17.96%	22
MAI Capital Management	Unchanged	181	$1,532	0.0%	+198.48%	0
JONES FINANCIAL COMPANIES LLLP	Unchanged	154	$1,303	0.0%	+262.13%	0
HRT FINANCIAL LP	Decreased	30,645(-84.5%)	$259	0.0%	+96.47%	0
BNP Paribas Asset Management Holding S.A.	Increased	1,769(+9.3%)	$15	0.0%	+164.00%	8
CIBC WORLD MARKETS CORP	Exited	0(-100.0%)	$56,453	0.0%	+151.84%	0
HSBC HOLDINGS PLC	Exited	0(-100.0%)	$504,192	0.0%	+47.05%	0
Optiver Holding B.V.	Exited	0(-100.0%)	$6,410	0.0%	+60.89%	0
Savant Capital, LLC	Exited	0(-100.0%)	$628,353	0.0%	+154.52%	0
Mariner, LLC	Exited	0(-100.0%)	$144,886	0.0%	+96.02%	0
PRUDENTIAL FINANCIAL INC	Exited	0(-100.0%)	$77,387	0.0%	+23.43%	0
Brevan Howard Capital Management LP	Exited	0(-100.0%)	$321,703	0.0%	+60.89%	0
Blackstone Inc.	Exited	0(-100.0%)	$185,926	0.0%	-74.99%	0
FEDERATED HERMES, INC.	Exited	0(-100.0%)	$187,920	0.0%	+118.81%	0

RELAY THERAPEUTICS INC

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