Summit Therapeutics Inc. (SMMT) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling SMMT?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for Summit Therapeutics Inc., showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on SMMT?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for Summit Therapeutics Inc..

Is institutional money flowing into SMMT?

113 institutional investors hold Summit Therapeutics Inc. (SMMT). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about SMMT?

Track institutional sentiment and conviction scores for Summit Therapeutics Inc. (SMMT) including Smart Money Verdict and position changes on HoldingsIntel.

Summit Therapeutics Inc.

SMMT·86627T108·US·equity·Healthcare - Biotechnology

SMMT (Summit Therapeutics Inc.) is held by 113 institutional investors as of Q4 2025. Largest holders: BAKER BROS. ADVISORS LP ($636.5M), FMR LLC ($233.7M), VANGUARD GROUP INC ($195.5M). Net institutional sentiment: Mixed.

113

Holders

Avg rating(10 Elite)

$1.8B

Total Value

51% (133)

Fund Consensus

63 buying - 61 selling

Smart Money VerdictView all

68Positive MomentumSplit Signals

Get 5 free verdicts/month - sign up in 10 seconds

See how SMMT's score breaks down across 4 SEC sources

Held by 113 funds

10 elite

Who's Trading

InsiderDUGGAN ROBERT WBuy $500KOct 21, 2025

Insider

13F: Dec 31, 2025Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BAKER BROS. ADVISORS LP	Increased	36.4M(+7.9%)	$636.5M	3.7%	+23.72%	63
FMR LLC	Increased	13.4M(+49.8%)	$233.7M	0.0%	-15.96%	42
VANGUARD GROUP INC	Decreased	11.2M(-1.8%)	$195.5M	0.0%	-27.40%	0
BlackRock, Inc.	Increased	9.4M(+27.1%)	$163.7M	0.0%	-15.99%	38
STATE STREET CORP	Increased	6.6M(+4.3%)	$116.1M	0.0%	+10.28%	31
GEODE CAPITAL MANAGEMENT, LLC	Increased	3.1M(+0.5%)	$55.1M	0.0%	+190.76%	29
CITADEL ADVISORS LLC	Increased	2.5M(+1121.3%)	$43.3M	0.0%	-14.92%	47
Pictet Asset Management Holding SA	Decreased	1.4M(-13.7%)	$24.4M	0.0%	-7.97%	0
TD ASSET MANAGEMENT INC	Increased	1.2M(+124.2%)	$21.1M	0.0%	-11.84%	46
Aberdeen Group plc	Decreased	927,171(-18.6%)	$16.2M	0.0%	-26.41%	0
MORGAN STANLEY	Decreased	926,579(-51.9%)	$16.2M	0.0%	-21.09%	0
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	892,629(+1.9%)	$15.6M	0.0%	+64.25%	29
UBS Group AG	Decreased	870,719(-31.9%)	$15.2M	0.0%	-17.11%	0
Squarepoint Ops LLC	Increased	715,410(+551.4%)	$12.5M	0.0%	-15.90%	45
TWO SIGMA INVESTMENTS, LP	Increased	578,248(+2210.2%)	$10.1M	0.0%	-14.39%	45
NOMURA HOLDINGS INC	Decreased	542,234(-48.3%)	$9.5M	0.0%	-28.42%	0
Candriam S.C.A.	Increased	540,662(+5.2%)	$9.5M	0.0%	-27.08%	29
NORTHERN TRUST CORP	Decreased	528,487(-3.3%)	$9.2M	0.0%	+366.96%	0
GOLDMAN SACHS GROUP INC	Decreased	485,566(-2.4%)	$8.5M	0.0%	-21.16%	0
BANK OF AMERICA CORP /DE/	Decreased	477,393(-27.4%)	$8.3M	0.0%	-21.12%	0
MILLENNIUM MANAGEMENT LLC	Increased	469,017(+289.2%)	$8.2M	0.0%	-5.84%	44
Invesco Ltd.	Increased	461,301(+8.3%)	$8.1M	0.0%	-4.10%	30
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Increased	440,953(+47.2%)	$7.7M	0.0%	-0.80%	38
TUDOR INVESTMENT CORP ET AL	Increased	423,084(+21.8%)	$7.4M	0.0%	-26.30%	33
D. E. Shaw & Co., Inc.	Increased	415,284(+217.9%)	$7.3M	0.0%	-17.98%	44
DIMENSIONAL FUND ADVISORS LP	Increased	376,563(+0.5%)	$6.6M	0.0%	-22.19%	27
Sculptor Capital LP	Increased	356,900(+7.0%)	$6.2M	0.1%	-27.77%	29
AQR CAPITAL MANAGEMENT LLC	Increased	357,870(+90.9%)	$6.2M	0.0%	-19.15%	43
Bank of New York Mellon Corp	Decreased	353,756(-3.6%)	$6.2M	0.0%	+94.82%	0
BARCLAYS PLC	Decreased	338,390(-28.9%)	$5.9M	0.0%	+15.21%	0
Skandinaviska Enskilda Banken AB (publ)	Unchanged	338,363	$5.9M	0.0%	-27.22%	0
Rafferty Asset Management, LLC	Decreased	287,810(-15.1%)	$5M	0.0%	-8.10%	0
SCHRODER INVESTMENT MANAGEMENT GROUP	Increased	251,391(+3.6%)	$4.4M	0.0%	-26.47%	28
DEUTSCHE BANK AG\	Decreased	237,788(-11.9%)	$4.2M	0.0%	-18.60%	0
Nuveen, LLC	Unchanged	232,642	$4.1M	0.0%	-26.32%	0
Verition Fund Management LLC	Increased	228,990(+38.3%)	$4M	0.0%	-23.45%	35
Woodline Partners LP	Unchanged	214,507	$3.8M	0.0%	-26.95%	0
WELLS FARGO & COMPANY/MN	Decreased	130,886(-32.1%)	$2.3M	0.0%	-13.36%	0
CITIGROUP INC	Decreased	129,926(-18.7%)	$2.3M	0.0%	-20.82%	0
RHUMBLINE ADVISERS	Decreased	121,341(-1.3%)	$2.1M	0.0%	+264.30%	0
CAPITAL FUND MANAGEMENT S.A.	Increased	113,391(+52.9%)	$2M	0.0%	-24.03%	36
Cerity Partners LLC	Decreased	112,878(-1.6%)	$2M	0.0%	-26.38%	0
VOYA INVESTMENT MANAGEMENT LLC	Decreased	112,437(-44.5%)	$2M	0.0%	+115.41%	0
Jefferies Financial Group Inc.	Increased	100,000(+566.7%)	$1.7M	0.0%	-16.24%	42
HSBC HOLDINGS PLC	New	98,766	$1.7M	0.0%	-13.61%	36
NEOS Investment Management LLC	Increased	97,217(+21.1%)	$1.7M	0.0%	-21.90%	31
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	96,009	$1.7M	0.0%	-7.06%	0
BANK OF MONTREAL /CAN/	Decreased	95,371(-2.7%)	$1.7M	0.0%	-21.33%	0
STATE OF WISCONSIN INVESTMENT BOARD	Increased	92,882(+1.1%)	$1.6M	0.0%	-28.45%	26
Focus Partners Wealth	Increased	88,448(+0.0%)	$1.5M	0.0%	-27.66%	25
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Increased	79,626(+0.1%)	$1.4M	0.0%	-26.65%	25
LMR Partners LLP	New	75,200	$1.3M	0.0%	-13.61%	35
Mariner, LLC	Decreased	73,497(-7.6%)	$1.3M	0.0%	-28.31%	0
JPMORGAN CHASE & CO	Decreased	67,422(-50.6%)	$1.2M	0.0%	-23.42%	0
DnB Asset Management AS	Increased	61,061(+97.5%)	$1.1M	0.0%	-20.23%	40
Assenagon Asset Management S.A.	New	59,621	$1M	0.0%	-13.61%	35
Farther Finance Advisors, LLC	Increased	57,282(+3.7%)	$1M	0.0%	-28.15%	26
AMERIPRISE FINANCIAL INC	Increased	54,012(+0.9%)	$944,670	0.0%	-23.78%	25
NEW YORK STATE COMMON RETIREMENT FUND	Decreased	53,777(-79.7%)	$940,560	0.0%	-19.93%	0
Police & Firemen's Retirement System of New Jersey	Increased	52,619(+0.2%)	$920,306	0.0%	-23.24%	25
BALYASNY ASSET MANAGEMENT L.P.	Decreased	50,298(-74.2%)	$879,712	0.0%	-28.59%	0
GUGGENHEIM CAPITAL LLC	Increased	49,798(+21.5%)	$870,967	0.0%	-17.20%	30
WORLDQUANT MILLENNIUM ADVISORS LLC	New	41,734	$729,928	0.0%	-13.61%	34
Beacon Pointe Advisors, LLC	Increased	39,611(+10.9%)	$692,797	0.0%	-27.36%	27
Mirae Asset Global Investments Co., Ltd.	Increased	37,991(+24.2%)	$664,463	0.0%	+45.87%	30
BNP PARIBAS FINANCIAL MARKETS	Increased	37,084(+27.1%)	$648,599	0.0%	-19.88%	30
Vident Advisory, LLC	Decreased	35,880(-2.1%)	$627,541	0.0%	-25.64%	0
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	Decreased	35,158(-3.7%)	$614,913	0.0%	-26.66%	0
ProShare Advisors LLC	Increased	32,881(+24.3%)	$575,089	0.0%	+179.68%	30
GROUP ONE TRADING LLC	Increased	31,410(+3.8%)	$549,361	0.0%	-28.13%	25
IMC-Chicago, LLC	New	29,704	$519,523	0.0%	-13.61%	33
FIRST TRUST ADVISORS LP	Decreased	28,115(-83.6%)	$491,731	0.0%	-28.59%	0
Legal & General Group Plc	Increased	27,359(+3.1%)	$478,509	0.0%	+8.42%	25
Schonfeld Strategic Advisors LLC	New	27,304	$477,545	0.0%	-13.61%	33
Eurizon Capital SGR S.p.A.	New	25,662	$448,828	0.0%	-13.61%	33
CIBC Asset Management Inc	Increased	24,289(+9.8%)	$424,815	0.0%	+53.95%	26
Steward Partners Investment Advisory, LLC	Increased	23,045(+15.7%)	$403,057	0.0%	-25.22%	27
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	Increased	20,875(+27.2%)	$389,528	0.0%	-24.79%	30
Allianz Asset Management GmbH	Unchanged	22,200	$388,278	0.0%	-8.11%	0
ALLIANCEBERNSTEIN L.P.	Increased	20,606(+1.9%)	$360,399	0.0%	+74.43%	24
RAYMOND JAMES FINANCIAL INC	Increased	17,851(+26.5%)	$312,214	0.0%	-24.54%	29
XPONANCE LLC	Increased	17,503(+2.7%)	$306,127	0.0%	-26.41%	24
Russell Investments Group, Ltd.	Decreased	16,966(-70.8%)	$296,735	0.0%	-24.71%	0
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Decreased	16,860(-6.3%)	$294,881	0.0%	+2.86%	0
Gotham Asset Management, LLC	Unchanged	15,727	$275,065	0.0%	+93.72%	0
Quantinno Capital Management LP	New	14,323	$250,509	0.0%	-13.61%	32
LPL Financial LLC	Decreased	13,160(-42.3%)	$230,168	0.0%	-27.00%	0
Creative Planning	Decreased	12,811(-17.3%)	$224,064	0.0%	+9.68%	0
Hudson Bay Capital Management LP	New	11,440	$200,086	0.0%	-13.61%	32
TWO SIGMA ADVISERS, LP	New	10,700	$187,143	0.0%	-13.61%	31
SEI INVESTMENTS CO	Decreased	10,063(-63.0%)	$176,002	0.0%	-26.71%	0
PRICE T ROWE ASSOCIATES INC /MD/	Increased	9.4M(+106.5%)	$163,907	0.0%	-12.32%	36
Federation des caisses Desjardins du Quebec	Decreased	8,613(-7.4%)	$150,641	0.0%	-28.59%	0
MetLife Investment Management, LLC	Increased	7,544(+0.9%)	$131,945	0.0%	+256.66%	22
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Decreased	7,270(-1.4%)	$127,152	0.0%	+50.64%	0
OSAIC HOLDINGS, INC.	Decreased	5,281(-3.9%)	$92,360	0.0%	-24.19%	0
ROYAL BANK OF CANADA	Decreased	3,196(-98.3%)	$56,000	0.0%	-27.61%	0
FIFTH THIRD BANCORP	Unchanged	3,000	$52,470	0.0%	-25.78%	0
STRS OHIO	Increased	2,798(+0.2%)	$48,937	0.0%	-26.63%	20
NATIONAL BANK OF CANADA /FI/	Increased	1,695(+121.9%)	$29,601	0.0%	-16.50%	21
Kestra Advisory Services, LLC	New	1,622	$28,369	0.0%	-13.61%	27
Empowered Funds, LLC	New	906	$15,846	0.0%	-13.61%	25
JONES FINANCIAL COMPANIES LLLP	Increased	548(+26.3%)	$9,585	0.0%	-16.72%	14
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	489(-72.7%)	$8,552	0.0%	-25.81%	0
Zurcher Kantonalbank (Zurich Cantonalbank)	Unchanged	424	$7,416	0.0%	+523.84%	0
US BANCORP \DE\	Decreased	325(-52.3%)	$5,684	0.0%	-25.80%	0
NISA INVESTMENT ADVISORS, LLC	Decreased	237(-21.3%)	$4,145	0.0%	-16.28%	0
Allworth Financial LP	Decreased	69(-80.7%)	$1,207	0.0%	-26.47%	0
ASSETMARK, INC	Decreased	44(-99.8%)	$770	0.0%	-26.65%	0
COMERICA BANK	Decreased	32(-95.8%)	$560	0.0%	-26.41%	0
CIBC Private Wealth Group LLC	New	3	$52	0.0%	-13.61%	17
NEW YORK LIFE INVESTMENT MANAGEMENT LLC	Exited	0(-100.0%)	$228,252	0.0%	-2.55%	0
Polar Capital Holdings Plc	Exited	0(-100.0%)	$15.4M	0.0%	-15.10%	0
STIFEL FINANCIAL CORP	Exited	0(-100.0%)	$554,348	0.0%	-15.10%	0
Brevan Howard Capital Management LP	Exited	0(-100.0%)	$234,511	0.0%	-15.10%	0
HighTower Advisors, LLC	Exited	0(-100.0%)	$222,260	0.0%	+333.37%	0
CI INVESTMENTS INC.	Exited	0(-100.0%)	$4	0.0%	-2.33%	0
Man Group plc	Exited	0(-100.0%)	$610,503	0.0%	-13.96%	0
Amundi	Exited	0(-100.0%)	$310,078	0.0%	-15.52%	0
Rockefeller Capital Management L.P.	Exited	0(-100.0%)	$682	0.0%	-17.34%	0
ENVESTNET ASSET MANAGEMENT INC	Exited	0(-100.0%)	$1.9M	0.0%	-15.10%	0
Fiera Capital Corp	Exited	0(-100.0%)	$15.7M	0.0%	-15.10%	0
Caption Management, LLC	Exited	0(-100.0%)	$583,934	0.0%	-15.10%	0
Orion Porfolio Solutions, LLC	Exited	0(-100.0%)	$418,943	0.0%	-12.47%	0
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Exited	0(-100.0%)	$5.1M	0.0%	-0.31%	0
XTX Topco Ltd	Exited	0(-100.0%)	$300,293	0.0%	-15.10%	0
Calamos Advisors LLC	Exited	0(-100.0%)	$384,854	0.0%	-16.26%	0
Optiver Holding B.V.	Exited	0(-100.0%)	$41	0.0%	-17.34%	0
Wealthspire Advisors, LLC	Exited	0(-100.0%)	$207	0.0%	-17.34%	0
NOMURA ASSET MANAGEMENT CO LTD	Unchanged	0	$0	0.0%	-15.54%	0
ExodusPoint Capital Management, LP	Exited	0(-100.0%)	$485,779	0.0%	-17.34%	0
Quadrature Capital Ltd	Exited	0(-100.0%)	$242,097	0.0%	-17.34%	0

Summit Therapeutics Inc.

Continue exploring