VYNE THERAPEUTICS INC

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VYNE·92941V308·US·equity·Healthcare - Biotechnology-13D/G

VYNE (VYNE THERAPEUTICS INC) is held by 18 institutional investors as of Q1 2026. Largest holders: CITADEL ADVISORS LLC ($307,380), TWO SIGMA INVESTMENTS, LP ($254,781), GEODE CAPITAL MANAGEMENT, LLC ($192,824). Net institutional sentiment: Mixed.

18

Holders

Avg rating(2 Elite)

$1.1M

Total Value

57% (22)

Fund Consensus

8 buying - 6 selling

Smart Money Verdict

View all

51Mixed MomentumSplit Signals

Institutional (13F)52

Insider (Form 4)

No data

Activist (13D/13G)49

Congressional (STOCK Act)

No data

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See how VYNE's score breaks down across 4 SEC sources

Holder Quality

2

★★★★★

Elite

7

★★★★

Strong

10

★★★

Solid

1

★★

Below

2

★

Weak

Held by 18 funds

2 elite

Who's Trading

ActivistNANantahala Capital Management, LLC6.0%May 15, 2026

ActivistCACormorant Asset Management, LP0.0%Nov 14, 2025

ActivistEAEventide Asset Management, LLC0.0%Nov 14, 2025

ActivistCitadel Advisors LLC0.0%Nov 14, 2025

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13F: Mar 31, 2026Insider & Congress: Updated regularly

Positions (18)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
CITADEL ADVISORS LLC	Increased	514,443(+1585.3%)	$307,380	0.0%	+13.91%	26
TWO SIGMA INVESTMENTS, LP	Increased	426,412(+93.8%)	$254,781	0.0%	+46.96%	37
GEODE CAPITAL MANAGEMENT, LLC	Increased	322,711(+43.3%)	$192,824	0.0%	-93.34%	21
UBS Group AG	Increased	179,784(+186.5%)	$107,511	0.0%	+17.05%	24
XTX Topco Ltd	Increased	158,396(+100.4%)	$94,642	0.0%	+16.52%	35
JANE STREET GROUP, LLC	Increased	95,645(+32.2%)	$57,148	0.0%	-38.70%	18
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	57,784(-42.4%)	$34,526	0.0%	-73.74%	0
BlackRock, Inc.	Unchanged	44,405	$26,532	0.0%	-79.00%	0
NORTHERN TRUST CORP	Unchanged	23,110	$13,808	0.0%	-71.16%	0
COMMONWEALTH EQUITY SERVICES, LLC	Unchanged	18,298	$10,930	0.0%	-63.59%	0
RENAISSANCE TECHNOLOGIES LLC	New	17,300	$10,337	0.0%	+13.56%	26
STATE STREET CORP	Unchanged	15,765	$9,420	0.0%	-70.04%	0
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	Unchanged	800	$478	0.0%	+19.64%	0
JPMORGAN CHASE & CO	Unchanged	146	$86	0.0%	-62.32%	0
WELLS FARGO & COMPANY/MN	Unchanged	65	$39	0.0%	-80.12%	0
MORGAN STANLEY	Unchanged	43	$26	0.0%	-66.97%	0
HRT FINANCIAL LP	New	27,569	$16	0.0%	+13.56%	17
ROYAL BANK OF CANADA	Decreased	15(-99.4%)	$0	0.0%	-78.99%	0
TWO SIGMA ADVISERS, LP	Exited	0(-100.0%)	$94,614	0.0%	+22.87%	0
Farther Finance Advisors, LLC	Exited	0(-100.0%)	$9	0.0%	-58.45%	0

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High Conviction Moves-Signal Convergence-Fund Consensus-Double-Down Signals

Data sourced from four SEC data sources: 13F, Form 4, 13D/13G, and STOCK Act. Not financial advice. Full disclaimer