VYNE THERAPEUTICS INC (VYNE) is held by 21 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is CITADEL ADVISORS LLC as of Q1 2026.

Are institutions buying or selling VYNE?

In Q1 2026, 11 institutions opened or increased positions in VYNE THERAPEUTICS INC while 5 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on VYNE?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for VYNE THERAPEUTICS INC.

How many hedge funds hold VYNE?

21 institutional investors report holding VYNE THERAPEUTICS INC (VYNE) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into VYNE?

As of Q1 2026, tracked institutions in VYNE THERAPEUTICS INC show 11 buyers versus 5 sellers — net inflows.

VYNE THERAPEUTICS INC

VYNE·92941V308·US·Common Stock·Healthcare - Biotechnology-13D/G

Holders

Avg rating(4 Elite)

$1.4M

Total Value

69% (24)

Fund Consensus

11 buying - 5 selling

Smart Money Verdict

View all

Held by 21 funds

4 elite

Who's Trading

ActivistZXZhang XiaofanJul 14, 2026

ActivistZXZhang Xiaofan5.6%Jun 15, 2026

ActivistNANantahala Capital Management, LLC6.0%May 15, 2026

Activist

Citadel Advisors LLC0.0%Nov 14, 2025

ActivistEAEventide Asset Management, LLC0.0%Nov 14, 2025

ActivistCACormorant Asset Management, LP0.0%Nov 14, 2025

View all activist filings

13F: Mar 31, 2026Insider & Congress: Updated regularly

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
CITADEL ADVISORS LLC	Increased	514,443(+1585.3%)	$307,380	0.0%	+8.81%	26
TWO SIGMA INVESTMENTS, LP	Increased	426,412(+93.8%)	$254,781	0.0%	+40.38%	37
GEODE CAPITAL MANAGEMENT, LLC	Increased	322,711(+43.3%)	$192,824	0.0%	-93.64%	21
VAVANGUARD CAPITAL MANAGEMENT LLC	New	264,557	$158,205	0.0%	+8.47%	34
VFVANGUARD FIDUCIARY TRUST CO	New	183,443	$109,699	0.0%	+8.47%	33
UBS Group AG	Increased	179,784(+186.5%)	$107,511	0.0%	+11.81%	24
XTX Topco Ltd	Increased	158,396(+100.4%)	$94,642	0.0%	+11.30%	35
JANE STREET GROUP, LLC	Increased	95,645(+32.2%)	$57,148	0.0%	-41.44%	18
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Decreased	57,784(-42.4%)	$34,526	0.0%	-74.92%	0
BlackRock, Inc.	Unchanged	44,405	$26,532	0.0%	-79.94%	0
NORTHERN TRUST CORP	Unchanged	23,110	$13,808	0.0%	-72.45%	0
COMMONWEALTH EQUITY SERVICES, LLC	Unchanged	18,298	$10,930	0.0%	-65.22%	0
RENAISSANCE TECHNOLOGIES LLC	New	17,300	$10,337	0.0%	+8.47%	26
STATE STREET CORP	Unchanged	15,765	$9,420	0.0%	-71.38%	0
VGVanguard Global Advisers, LLC	New	1,004	$600	0.0%	+8.47%	17
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	Unchanged	800	$478	0.0%	+14.29%	0
JPMORGAN CHASE & CO	Unchanged	146	$86	0.0%	-64.01%	0
WELLS FARGO & COMPANY/MN	Unchanged	65	$39	0.0%	-81.01%	0
MORGAN STANLEY	Unchanged	43	$26	0.0%	-68.45%	0
HRT FINANCIAL LP	New	27,569	$16	0.0%	+8.47%	17