XENON PHARMACEUTICALS INC

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XENE·98420N105·US·Common Stock·Healthcare - Biotechnology-13D/G

XENE (XENON PHARMACEUTICALS INC) is held by 153 institutional investors as of Q1 2026. Largest holders: FMR LLC ($629.1M), Avoro Capital Advisors LLC ($336M), BlackRock, Inc. ($328M). Net institutional sentiment: Bullish.

153

Holders

(25 Elite)

$4.6B

Total Value

71% (156)

Consensus

110 buying - 46 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)

Insider (Form 4)

Activist (13D/13G)

Congressional (STOCK Act)

Holder Quality

★★★★★

Elite

★★★★

Strong

★★★

Solid

★★

Below

★

Weak

Held by 153 funds

25 elite

Who's Trading

ActivistDRIEHAUS CAPITAL MANAGEMENT LLC4.9%May 15, 2026

ActivistAvoro Capital Advisors LLC6.3%May 15, 2026

ActivistJANUS HENDERSON GROUP PLC4.5%May 15, 2026

InsiderMIMORTIMER IANSell $404KMar 13, 2026

InsiderDADiFabio AndreaSell $74KMar 13, 2026

InsiderKJKENNEY CHRISTOPHER JOHNSell $78KMar 13, 2026

InsiderMIMORTIMER IANSell $677KMar 10, 2026

InsiderDADiFabio AndreaSell $157KMar 10, 2026

InsiderKJKENNEY CHRISTOPHER JOHNSell $167KMar 10, 2026

InsiderMIMORTIMER IANSell $2.6MMar 9, 2026

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Top Holders (153)History

AllNewIncreasedHeldDecreasedExited

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
FMR LLC	Increased	10.8M(+21.3%)	$629.1M	0.0%	+77.55%	38
Avoro Capital Advisors LLC	Increased	5.8M(+6.5%)	$336M	3.3%	+201.61%	62
BlackRock, Inc.	Increased	5.6M(+10.6%)	$328M	0.0%	+90.69%	34
WELLINGTON MANAGEMENT GROUP LLP	Increased	4.8M(+1.4%)	$280.8M	0.1%	+65.46%	31
DRIEHAUS CAPITAL MANAGEMENT LLC	Decreased	4.5M(-1.0%)	$261.2M	1.9%	+138.68%	0
Polar Capital Holdings Plc	Increased	4.4M(+78.7%)	$256.2M	0.9%	+81.42%	66
Janus Henderson Group Ltd.	Increased	4.2M(+2.3%)	$242.9M	0.1%	+78.37%	38
Capital International Investors	Decreased	2.7M(-21.7%)	$155.5M	0.0%	+144.33%	0
CITADEL ADVISORS LLC	Increased	2.7M(+100.8%)	$154.3M	0.0%	+64.35%	49
JPMORGAN CHASE & CO	Increased	1.9M(+28.8%)	$106.9M	0.0%	+72.22%	38
STATE STREET CORP	Increased	1.7M(+15.3%)	$100M	0.0%	+88.80%	34
Holocene Advisors, LP	Increased	1.5M(+18.4%)	$88.3M	0.2%	+98.90%	42
WESTFIELD CAPITAL MANAGEMENT CO LP	Increased	1.4M(+14.2%)	$81.5M	0.3%	+71.74%	41
BNP Paribas Asset Management Holding S.A.	Increased	1.3M(+26.6%)	$78M	0.1%	+62.30%	37
PRICE T ROWE ASSOCIATES INC /MD/	Increased	1.3M(+54.2%)	$77.3M	0.0%	+57.87%	42
JENNISON ASSOCIATES LLC	Increased	1.3M(+2.1%)	$76.7M	0.1%	+67.54%	30
AIAlyeska Investment Group, L.P.	New	1.3M	$75.6M	0.2%	+57.39%	49
FRANKLIN RESOURCES INC	Increased	1.3M(+68.9%)	$74.5M	0.0%	+67.57%	44
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.1M(+14.7%)	$63.5M	0.0%	+104.89%	34
ALLIANCEBERNSTEIN L.P.	Decreased	1.4M(-11.9%)	$62.9M	0.0%	+85.51%	0

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