XENCOR INC (XNCR) is held by institutional investors who disclose positions via SEC 13F filings. View the full list of institutional holders on HoldingsIntel.

Are institutions buying or selling XNCR?

HoldingsIntel tracks quarter-over-quarter changes in institutional positions for XENCOR INC, showing new buyers, position increases, decreases, and exits with conviction-weighted sentiment.

What is the Smart Money Verdict on XNCR?

The Smart Money Verdict combines four independent signals (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for XENCOR INC.

Is institutional money flowing into XNCR?

120 institutional investors hold XENCOR INC (XNCR). View detailed buyer/seller breakdown on HoldingsIntel.

What do hedge funds think about XNCR?

Track institutional sentiment and conviction scores for XENCOR INC (XNCR) including Smart Money Verdict and position changes on HoldingsIntel.

XENCOR INC

XNCR·98401F105·US·equity·Healthcare - Biotechnology-13D/G

XNCR (XENCOR INC) is held by 120 institutional investors as of Q4 2025. Largest holders: BlackRock, Inc. ($182.6M), PRIMECAP MANAGEMENT CO/CA/ ($156.4M), VANGUARD GROUP INC ($109.7M). Net institutional sentiment: Mixed.

120

Holders

Avg rating(8 Elite)

$941.6M

Total Value

46% (133)

Fund Consensus

52 buying - 63 selling

Smart Money Verdict- Q4 2025View all

45Weak MomentumSplit Signals

Held by 120 funds

8 elite

Who's Trading

ActivistRA Capital Management, L.P.6.5%Mar 30, 2026

Activist

13F: Dec 31, 2025Insider & Congress: Updated regularly

InsiderEckert CeliaSell $36KMar 5, 2026

InsiderCornelissen Bart JanSell $28KMar 5, 2026

InsiderDesjarlais John RSell $46KMar 5, 2026

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
BlackRock, Inc.	Increased	11.9M(+1.0%)	$182.6M	0.0%	-49.12%	31
PRIMECAP MANAGEMENT CO/CA/	Decreased	10.2M(-4.3%)	$156.4M	0.1%	-55.11%	0
VANGUARD GROUP INC	Increased	7.2M(+0.9%)	$109.7M	0.0%	-37.91%	30
RTW INVESTMENTS, LP	Increased	6.8M(+8.9%)	$103.8M	1.0%	-24.18%	52
STATE STREET CORP	Increased	4.5M(+22.7%)	$69M	0.0%	-36.23%	36
GEODE CAPITAL MANAGEMENT, LLC	Increased	1.8M(+1.4%)	$26.8M	0.0%	-59.15%	29
MORGAN STANLEY	Increased	1.5M(+67.5%)	$23.1M	0.0%	-25.57%	42
Legal & General Group Plc	Increased	1.3M(+2.8%)	$20M	0.0%	-15.58%	29
DIMENSIONAL FUND ADVISORS LP	Decreased	1.2M(-21.4%)	$19.1M	0.0%	-49.68%	0
BAKER BROS. ADVISORS LP	Unchanged	1.1M	$16.9M	0.1%	-33.63%	0
GOLDMAN SACHS GROUP INC	Decreased	753,258(-26.0%)	$11.5M	0.0%	-24.65%	0
Jefferies Financial Group Inc.	Increased	720,440(+620.4%)	$11M	0.1%	-17.37%	45
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Increased	700,435(+1.8%)	$10.7M	0.0%	-56.64%	28
NORTHERN TRUST CORP	Decreased	674,657(-5.3%)	$10.3M	0.0%	-58.02%	0
UBS Group AG	Decreased	638,021(-45.7%)	$9.8M	0.0%	-36.88%	0
BANK OF AMERICA CORP /DE/	Decreased	629,408(-16.5%)	$9.6M	0.0%	+18.15%	0
MILLENNIUM MANAGEMENT LLC	Decreased	594,435(-15.4%)	$9.1M	0.0%	+18.69%	0
PANAGORA ASSET MANAGEMENT INC	Decreased	583,778(-6.0%)	$8.9M	0.0%	+9.93%	0
TWO SIGMA ADVISERS, LP	Decreased	506,600(-37.5%)	$7.8M	0.0%	-27.86%	0
TORONTO DOMINION BANK	Increased	491,000(+882.0%)	$7.5M	0.0%	-18.10%	44
Erste Asset Management GmbH	Increased	480,200(+26.3%)	$7.3M	0.1%	-49.22%	34
Hudson Bay Capital Management LP	Decreased	425,000(-7.6%)	$6.5M	0.0%	+8.52%	0
Bank of New York Mellon Corp	Decreased	410,650(-3.6%)	$6.3M	0.0%	-68.13%	0
BARCLAYS PLC	Decreased	359,235(-40.2%)	$5.5M	0.0%	-0.89%	0
PRINCIPAL FINANCIAL GROUP INC	Decreased	340,326(-1.2%)	$5.2M	0.0%	-60.80%	0
CITADEL ADVISORS LLC	Decreased	321,808(-33.1%)	$4.9M	0.0%	+3.87%	0
JPMORGAN CHASE & CO	Decreased	303,979(-24.3%)	$4.7M	0.0%	-10.62%	0
TWO SIGMA INVESTMENTS, LP	Decreased	268,737(-57.3%)	$4.1M	0.0%	-26.78%	0
Invesco Ltd.	Increased	265,820(+5.7%)	$4.1M	0.0%	-36.32%	28
JACOBS LEVY EQUITY MANAGEMENT, INC	New	259,319	$4M	0.0%	-20.03%	37
PUBLIC SECTOR PENSION INVESTMENT BOARD	Decreased	247,242(-11.1%)	$3.8M	0.0%	-42.78%	0
DEUTSCHE BANK AG\	Increased	216,568(+378.8%)	$3.3M	0.0%	-29.93%	43
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	New	200,000	$3.1M	0.0%	-20.03%	37
Woodline Partners LP	Unchanged	193,117	$3M	0.0%	-40.67%	0
Trexquant Investment LP	Increased	175,152(+28.7%)	$2.7M	0.0%	-21.48%	33
AMERICAN CENTURY COMPANIES INC	Increased	174,603(+0.7%)	$2.7M	0.0%	-35.19%	26
RHUMBLINE ADVISERS	Decreased	165,797(-5.7%)	$2.5M	0.0%	-58.82%	0
AMERIPRISE FINANCIAL INC	Decreased	135,806(-7.4%)	$2.1M	0.0%	-55.55%	0
Nuveen, LLC	Unchanged	134,051	$2.1M	0.0%	+7.03%	0
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	Decreased	119,789(-27.9%)	$1.8M	0.0%	-55.69%	0
Swiss National Bank	Increased	119,600(+3.7%)	$1.8M	0.0%	-61.14%	27
CITIGROUP INC	Increased	112,275(+374.5%)	$1.7M	0.0%	-25.38%	41
AQR CAPITAL MANAGEMENT LLC	Increased	112,271(+29.3%)	$1.7M	0.0%	+12.10%	32
Rafferty Asset Management, LLC	Increased	97,749(+39.9%)	$1.5M	0.0%	-35.06%	34
FMR LLC	Increased	92,883(+25.6%)	$1.4M	0.0%	-4.08%	31
VOLORIDGE INVESTMENT MANAGEMENT, LLC	New	87,717	$1.3M	0.0%	-20.03%	35
MANUFACTURERS LIFE INSURANCE COMPANY, THE	Decreased	82,942(-12.8%)	$1.3M	0.0%	-53.43%	0
WELLS FARGO & COMPANY/MN	Increased	79,667(+45.5%)	$1.2M	0.0%	-28.27%	34
TD ASSET MANAGEMENT INC	Decreased	77,802(-9.3%)	$1.2M	0.0%	-58.48%	0
ALLIANCEBERNSTEIN L.P.	Unchanged	72,090	$1.1M	0.0%	-65.85%	0
INTECH INVESTMENT MANAGEMENT LLC	Increased	70,612(+138.6%)	$1.1M	0.0%	-23.80%	41
PRUDENTIAL FINANCIAL INC	Decreased	67,570(-6.2%)	$1M	0.0%	-59.07%	0
NEOS Investment Management LLC	New	61,362	$939,452	0.0%	-20.03%	35
ALPS ADVISORS INC	Increased	58,639(+72.3%)	$897,763	0.0%	-42.83%	37
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	Decreased	58,530(-0.1%)	$896,094	0.0%	-61.80%	0
Point72 Asset Management, L.P.	New	55,339	$847,240	0.0%	-20.03%	34
BNP PARIBAS FINANCIAL MARKETS	Decreased	48,687(-60.8%)	$745,398	0.0%	+10.38%	0
Schonfeld Strategic Advisors LLC	Increased	47,848(+274.9%)	$732,552	0.0%	-14.76%	40
Russell Investments Group, Ltd.	Increased	47,189(+293.1%)	$722,477	0.0%	-32.77%	40
Quantinno Capital Management LP	Increased	47,134(+4.5%)	$721,622	0.0%	+25.40%	26
FRANKLIN RESOURCES INC	Decreased	41,225(-7.7%)	$631,154	0.0%	-43.74%	0
MetLife Investment Management, LLC	Increased	40,212(+14.6%)	$615,646	0.0%	-54.18%	28
CIBC Private Wealth Group LLC	Decreased	40,017(-23.9%)	$612,660	0.0%	-39.67%	0
STATE OF WISCONSIN INVESTMENT BOARD	Increased	38,825(+109.3%)	$594,411	0.0%	-35.30%	39
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	Increased	38,448(+4.9%)	$587,042	0.0%	-36.48%	26
RAYMOND JAMES FINANCIAL INC	Increased	38,037(+127.4%)	$582,347	0.0%	-36.22%	39
TUDOR INVESTMENT CORP ET AL	New	34,794	$532,696	0.0%	-20.03%	34
RENAISSANCE TECHNOLOGIES LLC	Decreased	34,158(-82.1%)	$522,959	0.0%	+4.92%	0
XTX Topco Ltd	New	32,009	$490,058	0.0%	-20.03%	33
LOS ANGELES CAPITAL MANAGEMENT LLC	Decreased	34,097(-65.5%)	$481,790	0.0%	+39.16%	0
Cerity Partners LLC	Increased	31,302(+3.8%)	$479,233	0.0%	+33.85%	25
SUSQUEHANNA INTERNATIONAL GROUP, LLP	Increased	30,803(+16.4%)	$471,594	0.0%	-25.69%	28
WELLINGTON MANAGEMENT GROUP LLP	New	29,031	$444,465	0.0%	-20.03%	33
JANUS HENDERSON GROUP PLC	Unchanged	23,986	$367,106	0.0%	-63.80%	0
Brevan Howard Capital Management LP	Decreased	23,051(-53.2%)	$352,911	0.0%	+4.07%	0
State of Tennessee, Department of Treasury	Decreased	28,276(-8.8%)	$341,857	0.0%	-61.49%	0
BANK OF MONTREAL /CAN/	Increased	21,887(+0.1%)	$335,090	0.0%	-13.73%	23
LPL Financial LLC	Decreased	21,474(-16.7%)	$328,767	0.0%	-47.66%	0
HSBC HOLDINGS PLC	Increased	20,969(+0.5%)	$321,035	0.0%	+25.16%	24
Zurcher Kantonalbank (Zurich Cantonalbank)	Unchanged	20,480	$313,549	0.0%	-42.06%	0
JANE STREET GROUP, LLC	New	19,306	$295,575	0.0%	-20.03%	36
Man Group plc	Decreased	19,096(-52.9%)	$292,360	0.0%	+47.67%	0
NEW YORK STATE COMMON RETIREMENT FUND	Unchanged	18,989	$290,722	0.0%	-66.09%	0
Creative Planning	Increased	17,791(+39.8%)	$272,380	0.0%	+1.07%	31
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS	Decreased	17,679(-2.7%)	$270,665	0.0%	-56.04%	0
Police & Firemen's Retirement System of New Jersey	Decreased	17,627(-12.6%)	$269,869	0.0%	-39.05%	0
Arizona State Retirement System	Decreased	17,160(-3.9%)	$262,720	0.0%	-61.18%	0
COMERICA BANK	Decreased	17,015(-10.0%)	$260,499	0.0%	-39.74%	0
ProShare Advisors LLC	Increased	16,853(+6.5%)	$258,019	0.0%	-51.06%	25
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	Unchanged	16,579	$253,824	0.0%	-62.93%	0
Sanctuary Advisors, LLC	Decreased	15,896(-28.8%)	$243,368	0.0%	-27.38%	0
Rockefeller Capital Management L.P.	Decreased	15,545(-3.0%)	$237,994	0.0%	+4.07%	0
Mitsubishi UFJ Asset Management Co., Ltd.	Decreased	15,387(-47.7%)	$229,574	0.0%	-25.73%	0
YOUSIF CAPITAL MANAGEMENT, LLC	Decreased	17,825(-2.5%)	$225,308	0.0%	-69.16%	0
EP Wealth Advisors, LLC	Decreased	13,188(-0.8%)	$201,908	0.0%	-58.06%	0
VOYA INVESTMENT MANAGEMENT LLC	Decreased	12,923(-1.6%)	$197,851	0.0%	-53.03%	0
KLP KAPITALFORVALTNING AS	Increased	12,900(+5.7%)	$197,499	0.0%	-48.28%	24
Engineers Gate Manager LP	Decreased	12,713(-68.4%)	$194,636	0.0%	+47.67%	0
Centiva Capital, LP	New	12,299	$188,298	0.0%	-20.03%	31
Pictet Asset Management Holding SA	Unchanged	10,740	$164,429	0.0%	-49.30%	0
VICTORY CAPITAL MANAGEMENT INC	Decreased	10,658(-3.8%)	$163,174	0.0%	-56.38%	0
NISA INVESTMENT ADVISORS, LLC	Increased	6,500(+23.6%)	$99,515	0.0%	+0.15%	26
SIMPLEX TRADING, LLC	New	6,460	$98,902	0.0%	-20.03%	30
Ensign Peak Advisors, Inc	Decreased	5,577(-69.9%)	$85,384	0.0%	-55.05%	0
PNC FINANCIAL SERVICES GROUP, INC.	Decreased	5,573(-4.3%)	$85,323	0.0%	-33.60%	0
ROYAL BANK OF CANADA	Decreased	5,233(-98.5%)	$79,000	0.0%	+46.23%	0
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	New	5,277	$71,997	0.0%	-20.03%	29
Mirae Asset Global Investments Co., Ltd.	Increased	3,470(+25.9%)	$53,126	0.0%	-42.84%	25
Farther Finance Advisors, LLC	Decreased	2,773(-25.8%)	$42,455	0.0%	+4.07%	0
Allworth Financial LP	Increased	2,576(+0.3%)	$39,439	0.0%	-40.10%	20
PRICE T ROWE ASSOCIATES INC /MD/	Decreased	1.6M(-5.4%)	$24,524	0.0%	-51.99%	0
FEDERATED HERMES, INC.	Decreased	1,548(-60.8%)	$23,700	0.0%	-9.41%	0
GROUP ONE TRADING LLC	New	1,200	$18,372	0.0%	-20.03%	28
US BANCORP \DE\	Increased	819(+40.2%)	$12,539	0.0%	-12.76%	16
FIFTH THIRD BANCORP	Decreased	449(-30.8%)	$6,874	0.0%	-25.94%	0
HUNTINGTON NATIONAL BANK	Unchanged	322	$4,930	0.0%	+47.67%	0
OSAIC HOLDINGS, INC.	Decreased	116(-26.1%)	$1,776	0.0%	-20.01%	0
ASSETMARK, INC	New	20	$306	0.0%	-20.03%	17
BNP Paribas Asset Management Holding S.A.	New	690	$11	0.0%	-20.03%	17
HRT FINANCIAL LP	Exited	0(-100.0%)	$1,455	0.0%	+30.13%	0
Squarepoint Ops LLC	Exited	0(-100.0%)	$2.5M	0.0%	+77.16%	0
MARSHALL WACE, LLP	Exited	0(-100.0%)	$489,329	0.0%	+30.13%	0
MACQUARIE GROUP LTD	Exited	0(-100.0%)	$3.9M	0.0%	-28.06%	0
Optiver Holding B.V.	Exited	0(-100.0%)	$3,754	0.0%	+30.13%	0
NATIXIS	Exited	0(-100.0%)	$22,428	0.0%	+30.13%	0
Jain Global LLC	Exited	0(-100.0%)	$407,981	0.0%	+84.64%	0
Amundi	Exited	0(-100.0%)	$134,500	0.0%	-37.54%	0
Verition Fund Management LLC	Exited	0(-100.0%)	$251,315	0.0%	+70.57%	0
TEACHER RETIREMENT SYSTEM OF TEXAS	Exited	0(-100.0%)	$173,909	0.0%	-46.74%	0
Aberdeen Group plc	Exited	0(-100.0%)	$6.6M	0.0%	+12.45%	0
Wealthspire Advisors, LLC	Exited	0(-100.0%)	$364	0.0%	+30.13%	0
Assenagon Asset Management S.A.	Exited	0(-100.0%)	$286,658	0.0%	+30.13%	0

XENCOR INC

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