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IONS
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Position history for TWO SIGMA INVESTMENTS, LP's holdings in IONIS PHARMACEUTICALS INC

TWO SIGMA INVESTMENTS, LP holds 5.9M shares of IONS (IONIS PHARMACEUTICALS INC), worth $439.8M as of 2026-Q1. The position was increased (+120.3% shares). IONS represents 0.4% of TWO SIGMA INVESTMENTS, LP's portfolio.

Current Value

$439.8M

Current Shares

5.9M

Total Value Change

+$390.8M

Total Shares Change

+4.8M

Quarter-by-Quarter History
QuarterActionSharesChangeValueWeightPriceConviction
2026-Q1
Latest
Increased
5.9M
+120.3%
$439.8M0.4%$78.66
60
2025-Q4
Increased
2.7M
+68.7%
$210.3M0.3%$78.97
54
2025-Q3
Decreased
1.6M
-11.9%
$103.1M0.2%$64.15
0
2025-Q2
Increased
1.8M
+6.1%
$70.7M0.1%$39.80
38
2025-Q1
Increased
1.7M
+83.0%
$50.9M0.1%$31.15
54
2024-Q4
Increased
921,439
+0.3%
$32.2M0.1%$34.92
29
2024-Q3
Decreased
919,077
-10.6%
$36.8M0.1%$40.85
0
2024-Q2
Decreased
1M
-5.1%
$49M0.1%$47.66
0

Other major holders of IONS: FMR LLC, Capital World Investors

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